Program: B.Sc Nursing, 3rd Year
BNSG-501 MSN
Unit No.4.
Topic- Disorders of Menstrual Cycle
Lecture No. 8
Dr. Sudharani B Banappagoudar
Professor, SONS/OBG
1
BNSG 501
Outline
 Introduction
 Learning outcomes
 Exercise
 References
2
BNSG 501
TOPIC-REPRODUCTIVE TRACT ANAMOLIES
INTRODUCTION
FEMALE REPRODUCTIVE SYSTEM
INDIFFERENT EMBRYO
DEVELOPMENT OF GENITAL DUCTS
3
<SELO: 1,3,4,6,8,10,20>
<Reference No.: R1,R3>
BNSG 501
Objectives
• The student will be able to Explain
• Introduction
 Female reproductive system
 Indifferent embryo
 Development of genital ducts
4
<SELO: 1,3,4,6,8,10,20>
<Reference No.: R1,R2>
BNSG 501
• AMENORRHOEA
• Amenorrhoea is the absence of a
menstrual period in a woman of
reproductive age.
• Physiological states of amenorrhoea
are seen, most commonly, during
pregnancy and lactation
(breastfeeding), the latter also
contraception known as
forming the basis of a form of
the
lactational amenorrhoea method.
• Outside of the reproductive years
there is absence of menses during
childhood and after menopause.
• Primary amenorrhoea (menstrual cycles
never starting) may be caused by
developmental problems such as,
• the congenital absence of the uterus,
• failure of the ovary to receive or maintain
egg cells.
• It is defined as an absence of
secondary sexual characteristics by
age 14 with no menarche or normal
secondary sexual characteristics but
no menarche by 16 years of age.
• Secondary amenorrhoea (menstrual
cycles ceasing) is often caused by
hormonal disturbances from the
hypothalamus and the pituitary gland,
from premature menopause or
intrauterine scar formation.
• It is defined as the absence of
menses for three months in a woman
with previously normal menstruation or
nine months for women with a history
of oligomenorrhoea.
1. Natural amenorrhea
• During the normal course of life,
women may experience amenorrhea
for natural reasons, such as:
• Pregnancy
• Breast-feeding
• Menopause
2. Contraceptives
• Some women who take birth control
pills may not have periods. Even after
stopping oral contraceptives, it may
take some time before regular
ovulation and menstruation return.
Contraceptives that are injected or
implanted also may cause
amenorrhea, as can some types of
intrauterine devices.
3. Medications
• Certain medications can cause
menstrual periods to stop, including
some types of:
• Antipsychotics
• Cancer chemotherapy
• Antidepressants
• Blood pressure drugs
• Allergy medications
4. Lifestyle factors
• Sometimes lifestyle factors contribute to
amenorrhea, for instance:
• Low body weight. Excessively low body
weight — about 10 percent under normal
weight — interrupts many hormonal
functions in your body, potentially halting
ovulation. Women who have an eating
disorder, such as anorexia or bulimia,
often stop having periods because of
these abnormal hormonal changes.
• Excessive exercise. Women who
participate in activities that require rigorous
training, such as ballet, may find their
menstrual cycles interrupted. Several
factors combine to contribute to the loss of
periods in athletes, including low body fat,
stress and high energy expenditure.
• Stress. Mental stress can temporarily
alter the functioning of your
hypothalamus — an area of your
brain that controls the hormones that
regulate your menstrual cycle.
Ovulation and menstruation may stop
as a result. Regular menstrual
after your
periods usually resume
stress decreases.
5. Hormonal imbalance
• Many types of medical problems can
cause hormonal imbalance, including:
• Polycystic ovary syndrome (PCOS).
PCOS causes relatively high and
sustained levels of hormones, rather
than the fluctuating levels seen in the
normal menstrual cycle.
• Thyroid malfunction. An overactive
thyroid gland (hyperthyroidism) or
underactive thyroid gland
(hypothyroidism) can cause
menstrual irregularities, including
amenorrhea.
• Pituitary tumor. A noncancerous
(benign) tumor in your pituitary gland
can interfere with the hormonal
regulation of menstruation.
• Premature menopause. Menopause
usually begins around age 50. But,
for some women, the ovarian supply
of eggs diminishes before age 40,
and menstruation stops.
6. Structural problems
• Problems with the sexual
themselves also can
organs
cause
amenorrhea. Examples include:
• Uterine scarring. Asherman's
syndrome, a condition in which scar
tissue builds up in the lining of the
uterus, can sometimes occur after a
dilation and curettage (D&C), cesarean
section or treatment for uterine fibroids.
Uterine scarring prevents the normal
buildup and shedding of the uterine
lining.
• Lack of reproductive organs.
Sometimes problems arise during
fetal development that lead to a girl
being born without some major part of
her reproductive system, such as her
uterus, cervix or vagina. Because her
reproductive system didn't develop
normally, she can't have menstrual
cycles.
• Structural abnormality of the
vagina. An obstruction of the vagina
may prevent visible menstrual
bleeding. A membrane or wall may be
present in the vagina that blocks the
outflow of blood from the uterus and
cervix.
• The main sign of amenorrhea is
the absence of menstrual periods.
Depending on the cause of
amenorrhea, you might experience
other signs or symptoms along with
the absence of periods, such as:
• Milky nipple discharge
• Hair loss
• Headache
• Vision changes
• Excess facial hair
• Pelvic pain
• Acne
• Vaginal dryness
• Night sweats
• History collection
• Physical examination
• Blood tests may be performed to
determine the levels of hormones
secreted by the pituitary gland (FSH,
LH, TSH, and prolactin) and the
ovaries (estrogen).
• Ultrasonography of the pelvis may be
performed to assess the abnormalities
of the genital tract or to look for
polycystic ovaries.
• CT scan or MRI of the head may be
performed to exclude pituitary and
hypothalamic causes of amenorrhea.
• If the above tests are inconclusive,
additional tests may be performed
including:
• Thyroid function tests
• Determination of prolactin levels
• Hysterosalpingogram (X-ray test)
which examine the uterus
• Hysteroscopy
• Dopamine agonists such as bromocriptine
(Parlodel) or pergolide (Permax), are
effective in treating hyperprolactinemia. In
most women, treatment with dopamine
agonists medications restores normal
ovarian endocrine function and ovulation.
• Hormone replacement therapy consisting
of an estrogen and a progestin can be used
for women in whom estrogen deficiency
remains because ovarian function cannot be
restored.
• Metformin (Glucophage) is a drug
that has been successfully used in
women with polycystic ovary
syndrome to induce ovulation.
• In some cases, oral contraceptives may
be prescribed to restore the menstrual
cycle and to provide estrogen
replacement to women with amenorrhea
who do not wish to become pregnant.
• Before administering oral contraceptives,
withdrawal bleeding is induced with an
administration of 5-10 mg
injection of progesterone or oral
of
10
medroxyprogesterone (Provera) for
days.
• Some pituitary and hypothalamic
tumors may require surgery and, in
some cases, radiation therapy.
• Women with intrauterine adhesions
require dissolution of the scar tissue.
•PREMENSTRUAL
SYNDROME
(PMS)
• Premenstrual syndrome (PMS) refers
to physical and emotional symptoms
that occur in the one to two weeks
before a woman's period. Symptoms
often vary between women and
resolve around the start of bleeding.
• Common symptoms include acne,
tender breasts, bloating, feeling tired,
irritability, and mood changes. Often
symptoms are present for around six
days.
• Premenstrual dysphoric disorder
(PMDD) is a more severe form of PMS
that has greater psychological
symptoms.
• Exactly what causes premenstrual
syndrome is unknown, but several
factors may contribute to the
condition:
• Cyclic changes in hormones. Signs
and symptoms of premenstrual
syndrome change with hormonal
fluctuations and disappear with
pregnancy and menopause.
• Chemical changes in the brain.
Fluctuations of serotonin, a brain
chemical (neurotransmitter) that is
thought to play a crucial role in mood
states, could trigger PMS symptoms.
Insufficient amounts of serotonin may
contribute to premenstrual
depression, as well as to fatigue, food
cravings and sleep problems.
 Emotional and behavioral symptoms
• Tension or anxiety
• Depressed mood
• Crying spells
• Mood swings and irritability or anger
• Appetite changes and food cravings
• Trouble falling asleep (insomnia)
• Social withdrawal
• Poor concentration
Physical signs and symptoms
• Joint or muscle pain
• Headache
• Fatigue
• Weight gain related to fluid retention
• Abdominal bloating
• Breast tenderness
• Acne
• Constipation or diarrhea
are no unique physical
or laboratory tests to
diagnose premenstrual
• There
findings
positively
syndrome.
• Antidepressants. Selective serotonin
reuptake inhibitors (SSRIs) — which
include fluoxetine (Prozac, Sarafem),
paroxetine (Paxil, Pexeva), sertraline
(Zoloft) and others — have been
successful in reducing mood symptoms.
SSRIs are the first line treatment for
severe PMS or PMDD. These drugs are
generally taken daily. But for some
women with PMS, use of
antidepressants may be limited to the
two weeks before menstruation
begins.
• Nonsteroidal anti-inflammatory
drugs (NSAIDs). Taken before or at
the onset of your period, NSAIDs
such as ibuprofen (Advil, Motrin IB,
others) or naproxen (Aleve,
Naprosyn, others) can ease cramping
and breast discomfort.
• Diuretics. When exercise and limiting
salt intake aren't enough to reduce
the weight gain, swelling and bloating
of PMS, taking water pills (diuretics)
can help your body shed excess fluid
through your kidneys.
Spironolactone (Aldactone) is a
diuretic that can help ease some of
the symptoms of PMS.
• Hormonal contraceptives. These
prescription medications stop
ovulation, which may bring relief from
PMS symptoms.
• Eat smaller, more-frequent meals to reduce
bloating and the sensation of fullness.
• Limit salt and salty foods to reduce bloating
and fluid retention.
• Choose foods high in complex carbohydrates,
such as fruits, vegetables and whole grains.
• Choose foods rich in calcium. If you can't
tolerate dairy products or aren't getting
adequate calcium in your diet, a daily calcium
supplement may help.
• Avoid caffeine and alcohol.
• Engage in at least 30 minutes of brisk
walking, cycling, swimming or other
aerobic activity most days of the
week. Regular daily exercise can help
improve your overall health and
alleviate certain symptoms, such as
fatigue and a depressed mood.
• Get plenty of sleep.
• Practice progressive muscle
relaxation or deep-breathing
exercises to help reduce headaches,
anxiety or trouble sleeping
(insomnia).
• Try yoga or massage to relax and
relieve stress.
• Keep a record to identify the triggers
and timing of your symptoms. This
will allow you to intervene with
strategies that may help to lessen
them.

16.04.20 disordersofmenstruation.pptx

  • 1.
    Program: B.Sc Nursing,3rd Year BNSG-501 MSN Unit No.4. Topic- Disorders of Menstrual Cycle Lecture No. 8 Dr. Sudharani B Banappagoudar Professor, SONS/OBG 1 BNSG 501
  • 2.
    Outline  Introduction  Learningoutcomes  Exercise  References 2 BNSG 501
  • 3.
    TOPIC-REPRODUCTIVE TRACT ANAMOLIES INTRODUCTION FEMALEREPRODUCTIVE SYSTEM INDIFFERENT EMBRYO DEVELOPMENT OF GENITAL DUCTS 3 <SELO: 1,3,4,6,8,10,20> <Reference No.: R1,R3> BNSG 501
  • 4.
    Objectives • The studentwill be able to Explain • Introduction  Female reproductive system  Indifferent embryo  Development of genital ducts 4 <SELO: 1,3,4,6,8,10,20> <Reference No.: R1,R2> BNSG 501
  • 6.
  • 7.
    • Amenorrhoea isthe absence of a menstrual period in a woman of reproductive age.
  • 8.
    • Physiological statesof amenorrhoea are seen, most commonly, during pregnancy and lactation (breastfeeding), the latter also contraception known as forming the basis of a form of the lactational amenorrhoea method. • Outside of the reproductive years there is absence of menses during childhood and after menopause.
  • 9.
    • Primary amenorrhoea(menstrual cycles never starting) may be caused by developmental problems such as, • the congenital absence of the uterus, • failure of the ovary to receive or maintain egg cells.
  • 10.
    • It isdefined as an absence of secondary sexual characteristics by age 14 with no menarche or normal secondary sexual characteristics but no menarche by 16 years of age.
  • 11.
    • Secondary amenorrhoea(menstrual cycles ceasing) is often caused by hormonal disturbances from the hypothalamus and the pituitary gland, from premature menopause or intrauterine scar formation. • It is defined as the absence of menses for three months in a woman with previously normal menstruation or nine months for women with a history of oligomenorrhoea.
  • 12.
    1. Natural amenorrhea •During the normal course of life, women may experience amenorrhea for natural reasons, such as: • Pregnancy • Breast-feeding • Menopause
  • 13.
    2. Contraceptives • Somewomen who take birth control pills may not have periods. Even after stopping oral contraceptives, it may take some time before regular ovulation and menstruation return. Contraceptives that are injected or implanted also may cause amenorrhea, as can some types of intrauterine devices.
  • 14.
    3. Medications • Certainmedications can cause menstrual periods to stop, including some types of: • Antipsychotics • Cancer chemotherapy • Antidepressants • Blood pressure drugs • Allergy medications
  • 15.
    4. Lifestyle factors •Sometimes lifestyle factors contribute to amenorrhea, for instance: • Low body weight. Excessively low body weight — about 10 percent under normal weight — interrupts many hormonal functions in your body, potentially halting ovulation. Women who have an eating disorder, such as anorexia or bulimia, often stop having periods because of these abnormal hormonal changes.
  • 16.
    • Excessive exercise.Women who participate in activities that require rigorous training, such as ballet, may find their menstrual cycles interrupted. Several factors combine to contribute to the loss of periods in athletes, including low body fat, stress and high energy expenditure.
  • 17.
    • Stress. Mentalstress can temporarily alter the functioning of your hypothalamus — an area of your brain that controls the hormones that regulate your menstrual cycle. Ovulation and menstruation may stop as a result. Regular menstrual after your periods usually resume stress decreases.
  • 18.
    5. Hormonal imbalance •Many types of medical problems can cause hormonal imbalance, including: • Polycystic ovary syndrome (PCOS). PCOS causes relatively high and sustained levels of hormones, rather than the fluctuating levels seen in the normal menstrual cycle.
  • 19.
    • Thyroid malfunction.An overactive thyroid gland (hyperthyroidism) or underactive thyroid gland (hypothyroidism) can cause menstrual irregularities, including amenorrhea.
  • 20.
    • Pituitary tumor.A noncancerous (benign) tumor in your pituitary gland can interfere with the hormonal regulation of menstruation.
  • 21.
    • Premature menopause.Menopause usually begins around age 50. But, for some women, the ovarian supply of eggs diminishes before age 40, and menstruation stops.
  • 22.
    6. Structural problems •Problems with the sexual themselves also can organs cause amenorrhea. Examples include: • Uterine scarring. Asherman's syndrome, a condition in which scar tissue builds up in the lining of the uterus, can sometimes occur after a dilation and curettage (D&C), cesarean section or treatment for uterine fibroids. Uterine scarring prevents the normal buildup and shedding of the uterine lining.
  • 23.
    • Lack ofreproductive organs. Sometimes problems arise during fetal development that lead to a girl being born without some major part of her reproductive system, such as her uterus, cervix or vagina. Because her reproductive system didn't develop normally, she can't have menstrual cycles.
  • 24.
    • Structural abnormalityof the vagina. An obstruction of the vagina may prevent visible menstrual bleeding. A membrane or wall may be present in the vagina that blocks the outflow of blood from the uterus and cervix.
  • 25.
    • The mainsign of amenorrhea is the absence of menstrual periods. Depending on the cause of amenorrhea, you might experience other signs or symptoms along with the absence of periods, such as: • Milky nipple discharge • Hair loss
  • 26.
    • Headache • Visionchanges • Excess facial hair • Pelvic pain • Acne • Vaginal dryness • Night sweats
  • 27.
    • History collection •Physical examination • Blood tests may be performed to determine the levels of hormones secreted by the pituitary gland (FSH, LH, TSH, and prolactin) and the ovaries (estrogen).
  • 28.
    • Ultrasonography ofthe pelvis may be performed to assess the abnormalities of the genital tract or to look for polycystic ovaries. • CT scan or MRI of the head may be performed to exclude pituitary and hypothalamic causes of amenorrhea.
  • 29.
    • If theabove tests are inconclusive, additional tests may be performed including: • Thyroid function tests • Determination of prolactin levels • Hysterosalpingogram (X-ray test) which examine the uterus • Hysteroscopy
  • 30.
    • Dopamine agonistssuch as bromocriptine (Parlodel) or pergolide (Permax), are effective in treating hyperprolactinemia. In most women, treatment with dopamine agonists medications restores normal ovarian endocrine function and ovulation. • Hormone replacement therapy consisting of an estrogen and a progestin can be used for women in whom estrogen deficiency remains because ovarian function cannot be restored.
  • 31.
    • Metformin (Glucophage)is a drug that has been successfully used in women with polycystic ovary syndrome to induce ovulation.
  • 32.
    • In somecases, oral contraceptives may be prescribed to restore the menstrual cycle and to provide estrogen replacement to women with amenorrhea who do not wish to become pregnant. • Before administering oral contraceptives, withdrawal bleeding is induced with an administration of 5-10 mg injection of progesterone or oral of 10 medroxyprogesterone (Provera) for days.
  • 33.
    • Some pituitaryand hypothalamic tumors may require surgery and, in some cases, radiation therapy. • Women with intrauterine adhesions require dissolution of the scar tissue.
  • 34.
  • 35.
    • Premenstrual syndrome(PMS) refers to physical and emotional symptoms that occur in the one to two weeks before a woman's period. Symptoms often vary between women and resolve around the start of bleeding.
  • 36.
    • Common symptomsinclude acne, tender breasts, bloating, feeling tired, irritability, and mood changes. Often symptoms are present for around six days. • Premenstrual dysphoric disorder (PMDD) is a more severe form of PMS that has greater psychological symptoms.
  • 37.
    • Exactly whatcauses premenstrual syndrome is unknown, but several factors may contribute to the condition: • Cyclic changes in hormones. Signs and symptoms of premenstrual syndrome change with hormonal fluctuations and disappear with pregnancy and menopause.
  • 38.
    • Chemical changesin the brain. Fluctuations of serotonin, a brain chemical (neurotransmitter) that is thought to play a crucial role in mood states, could trigger PMS symptoms. Insufficient amounts of serotonin may contribute to premenstrual depression, as well as to fatigue, food cravings and sleep problems.
  • 39.
     Emotional andbehavioral symptoms • Tension or anxiety • Depressed mood • Crying spells • Mood swings and irritability or anger
  • 40.
    • Appetite changesand food cravings • Trouble falling asleep (insomnia) • Social withdrawal • Poor concentration
  • 41.
    Physical signs andsymptoms • Joint or muscle pain • Headache • Fatigue • Weight gain related to fluid retention • Abdominal bloating • Breast tenderness • Acne • Constipation or diarrhea
  • 42.
    are no uniquephysical or laboratory tests to diagnose premenstrual • There findings positively syndrome.
  • 43.
    • Antidepressants. Selectiveserotonin reuptake inhibitors (SSRIs) — which include fluoxetine (Prozac, Sarafem), paroxetine (Paxil, Pexeva), sertraline (Zoloft) and others — have been successful in reducing mood symptoms. SSRIs are the first line treatment for severe PMS or PMDD. These drugs are generally taken daily. But for some women with PMS, use of antidepressants may be limited to the two weeks before menstruation begins.
  • 44.
    • Nonsteroidal anti-inflammatory drugs(NSAIDs). Taken before or at the onset of your period, NSAIDs such as ibuprofen (Advil, Motrin IB, others) or naproxen (Aleve, Naprosyn, others) can ease cramping and breast discomfort.
  • 45.
    • Diuretics. Whenexercise and limiting salt intake aren't enough to reduce the weight gain, swelling and bloating of PMS, taking water pills (diuretics) can help your body shed excess fluid through your kidneys. Spironolactone (Aldactone) is a diuretic that can help ease some of the symptoms of PMS.
  • 46.
    • Hormonal contraceptives.These prescription medications stop ovulation, which may bring relief from PMS symptoms.
  • 47.
    • Eat smaller,more-frequent meals to reduce bloating and the sensation of fullness. • Limit salt and salty foods to reduce bloating and fluid retention. • Choose foods high in complex carbohydrates, such as fruits, vegetables and whole grains. • Choose foods rich in calcium. If you can't tolerate dairy products or aren't getting adequate calcium in your diet, a daily calcium supplement may help. • Avoid caffeine and alcohol.
  • 48.
    • Engage inat least 30 minutes of brisk walking, cycling, swimming or other aerobic activity most days of the week. Regular daily exercise can help improve your overall health and alleviate certain symptoms, such as fatigue and a depressed mood.
  • 49.
    • Get plentyof sleep. • Practice progressive muscle relaxation or deep-breathing exercises to help reduce headaches, anxiety or trouble sleeping (insomnia). • Try yoga or massage to relax and relieve stress.
  • 50.
    • Keep arecord to identify the triggers and timing of your symptoms. This will allow you to intervene with strategies that may help to lessen them.