2
Jumbled letters ofcell parts/structures.
Arrange the following jumbled letters of cell
parts/structures and write your answer on the right corner.
ANSWER
1.Ueslcun
2. Htoosm odenmicplas
iterumluc
3. Ghour
cimsalpodnecluumiter
4. Ggiolustarapap
5. Esmosobir
6. Semossoyl
7. Hcnordaiotmi
8. tsplaorohlc
3.
LEARNING
OBJECTIVES
At the endof the module, the
learners will be able to:
1. Describe the structure and
functions of major and
subcellular organelles.
2. Determine the role of each
cellular organelle and explain
how it relates to the functions
of the other.
3
MAJOR PARTS OFTHE CELL
• Plasma Membrane
• Cytoplasm
• Nucleus
6
7.
Plasma Membrane
7
Encloses andsafeguards its
organelles from possible harm
that foreign materials can inflict
on them.
It also controls the exchange
of essential components and
obtains chemical messages from
other cells.
8.
Plasma Membrane:
FLUID MOSAICMODEL
• The plasma
membrane is a mosaic
of components-
primarily,
phospholipids,
cholesterol, and
proteins- that move
freely and fluidly in
the plane of the
membrane
8
Cytoplasm
It is theentire region of a cell
between plasma membrane and
nuclear envelope.
It is composed primarily of water,
proteins, and salts.
The organelles are suspended in a
gel-like solution called cytosol,
which is composed of both organic
and inorganic compounds.*
Cytoplasm determines cell shape
and accommodates movement for
some cell types.
11.
Nucleus
Discovered by
Robert Brown
in1833.
It is the most vital part of the
cell and dubbed as the
“control center” of the cell.
It directs all the cell’s activities
and determines how a cell
should appear and function.
*Nucleolus serves as the site of ribosomes
synthesis. Nucleus holds chromosomes which
carry tightly wrapped and coined DNA.
12.
Cell Organelles:
Endomembrane
System
Made upof organelles like
endoplasmic reticulum,
ribosomes, vacuoles, Golgi
apparatus, lysosomes,
peroxisomes and
centrosomes.
The functions of the Cell
Organelles: Maintain the
shape and the structure of
the cell; acts as storage of
nutrients; production of
macromolecules; harvest
energy; repair cell parts;
and digest substances.
13.
Endoplasmic Reticulum
13
Endoplasmic
Reticulum
(ER)
a seriesof
interconnected
membranous
sacs and
tubules that
collectively
modifies
proteins and
synthesized
lipids.*
Rough
endoplasmic
reticulum
(RER)
has ribosomes
on its surface.
It makes
membrane
proteins and
proteins for
export out
of the cell.**
Smooth
endoplasmic
reticulum
(SER)
incorporates
proteins into
cisternae and
transports
synthesized
proteins across
the cytoplasm,
thereby allowing
the synthesis of
fatty acid and
phospholipids.***
14.
Ribosomes
14
involved inproviding
a frame for proteins
synthesis; hence they
are site of protein
production. *
15.
Vacuoles
15
A vacuoleis a fluid-filled
vesicles enclosed by a
membrane.
It has a selectively
membrane freely allowing
water passage but
retaining smaller
molecules within it and
stores chemicals
within the cell.*
16.
Golgi Apparatus
They arestacks of flattened
sacs, having a shipping side
(cis face) and a receiving
side (trans face).
Modify, sort, and
package received
proteins made by ER and
transport vesicles with
modified proteins pinch off
the ends.
16
17.
Lysosomes
The lysosomes
serve as
digestionslots
for cellular
materials that
are due for
expiration or
are no longer
useful.
It is
dubbed
as the
cell’s
“suicide
bags”. **
Lysosomes
digest the
food and get
rid of wastes,
example is
macrophages.
18.
Peroxisome
18
It is asmall,
round
organelles
enclosed by
single
membrane,
somehow
resembles that
of a lysosome.
Responsible
for self-
damage and
mostly
disintegrate
proteins,
accommodat
e the
breakdown of
fatty acids
and detoxify
many poisons
that enter
the body.
also shields
the cell from
serious
damage
caused
reactive
oxygen
species
(ROS)
molecules.
19.
Centrosome
19
• It comprisedof two centrioles or cylindrical
structures with a central cavity surrounded
by microtubules arranged side by side.
• These structure take part in the assembly of
spindle fibers at cell division and contribute
to the successful outcome of mitosis.
• It is found in all eukaryotic cells, assist in
arranging microtubules (hollow tubes of
proteins) to be utilized for cell division. *
20.
Mitochondria
20
sites of cellularrespiration, the metabolic process that
uses oxygen to drive the generation of ATP by
extracting energy from sugars, fats, and other fuels.
Mitochondria are oval-shaped organelles
found in most eukaryotic cells.
the “powerhouses” of the cell.
2 membranes:
Outer membrane* and Inner membrane**
21.
Chloroplast
found in plantsand algae, and they are the
sites of photosynthesis.
The chloroplasts are double membrane-
bound organelles.
The chloroplast has a system of three
membranes: the outer membrane, the inner
membrane and the thylakoid system
22.
Summary
• The cellhas three major parts: the cell membrane,
the nucleus, and the cytoplasm.
– The cell membrane functions as the cell’s
protection as it controls the movement of
materials in and out of the cell.
– The cytoplasm, found in all cells, is where
organelles are suspended inside the cell
membrane.
– The nucleus is the control center of the cell;
directs all cell activities, contains the DNA, or
the hereditary material of the cell.
23.
Summary
• The endomembranesystem is made up of organelles
that move materials across the membrane, such as the
endoplasmic reticulum, ribosomes, lysosomes,
centrosomes, peroxisomes, Golgi apparatus and
vacuoles.
• The endoplasmic reticulum serves to connect the
nuclear envelope and the cell membrane by carrying
materials through it.
• Ribosomes functions to synthesize protein.
• Lysosomes breaks down larger food molecules into
smaller molecule, even digesting old cell parts.
24.
Summary
• Peroxisomes assembledfrom proteins and
synthesized on free ribosomes and involved in variety
of metabolic reactions.
• Golgi apparatus are essential for the package and
export of proteins.
• Vacuoles function to store food, water, and other
metabolic and toxic wastes.
• Centromeres contain two centrioles that are mainly
active at cell division.
• The mitochondrion role is to generate ATP, the unit of
cellular energy.
• Chloroplast is essential in photosynthesis.
#4 *It makes up all living things, from the simplest to the most complex – from bacteria to plants and animals.
**that controls all the chemicals and molecules that help sustain an organism’s existence.
#5 *The differences of each reflect their uniqueness in terms of function.
Understanding the biological functions of the cell is necessary to get a good grasp of the complexity of cellular interactions, which direct, generate, and sustain life.
#6 Plasma Membrane is the outer covering that separates the cell’s interior from its surrounding
environment.
Cytoplasm consist of a jelly-like cytosol within the cell in which other cellular components
are found.
Nucleus serves as the brain of the cell and directs all of the cell’s activity.
#9 *Phospholipids is a lipid made of glycerol, two fatty acid tails, and a phophate-linked head group. Biological membranes usually involve two layers of phospholipids with their tails pointing inward, an arrangement called a phospholipid bilayer.
Cholesterol is another lipid composed of four fused carbon rings and is found alongside phospholipids in the core of the membrane.
Proteins help move large molecules or aid in cell recognition. Peripheral proteins are attached on the surface (inner or outer). Integral proteins are embedded completely through the membrane.
#10 *Cytosol accounts for about 70% of cellular content. It contains a rich supply of macromolecules and smaller organic molecules. The cytoplasm also contains enzymes that break down waste and enable metabolic reactions. It allows for cellular expansion and growth.
#11 * A double layer of nuclear membrane encloses the nucleus to keep it distinct from other cellular components.
#13 *The hollow portion of ER tubules is called lumen or cisternal space. The membrane of the ER, which is a phospholipid bilayer embedded with proteins, is continuous with nuclear envelope.
**Proteins are made up by ribosomes on ER surface. They are then threaded into the interior of the RER to be modified and transported.
***It is abundant in liver cell, where it detoxifies hydrophobic chemicals. This makes them water-soluble for excretion.
#14 *They are present in both prokaryotic and eukaryotic cells.
Developing muscle cells, skin, and hair cells contain large numbers of free ribosomes.
#15 *Vacuoles ability to break down large molecules makes it comparable with lysosomes in animal cells. Likewise, both organelles thrive in acidic environment.
#17 *It is the cell’s reprocessing area, where it hacks chemical bonds of any foreign substance it comes contact with, in order to recycle with the raw material.
**These organelles are capable for self-destruction in order to save the rest of the other organelles from being poisoned. This happens through autophagy, or the natural process of organelle destruction. Cells take in food by phagocytosis.
#19 *They also enable the said microtubules to form part of the cell’s microtubules to form part of the cell’s cytoskeleton. In this way, cellular shape is maintaining and the cell structure is stabilized.
#20 *Outer membrane is selectively permeable membrane that surrounds the mitochondria, it is the site of attachment for the respiratory assembly of the electron transport chain and ATP Synthase, and it has integral proteins and pores for transporting molecules just like the cell membrane
**Inner membrane folds inward (called cristae) to increase surfaces for cellular metabolism, and it contains ribosomes and the DNA of the mitochondria. The inner membrane creates two enclosed spaces within the mitochondria: Intermembrane space between the outer membrane and the inner membrane; and matrix that is enclosed within inner membrane.
#21 Outer membrane is a semi-porous membrane and is permeable to small molecules and ions which diffuse easily, it is not permeable to larger proteins. Intermembrane space is usually a thin intermembrane space about 10-20 nanometers and is present between the outer and the inner membrane of the chloroplast. The inner membrane of the chloroplast forms a border to the stroma. It regulates passage of materials in and out of the chloroplast. In addition to the regulation activity, fatty acids, and are synthesized in the inner chloroplast membrane. Stroma is an alkaline, aqueous fluid that is protein-rich and is present within the inner membrane of the chloroplast. It is the space outside the thylakoid space. The chloroplast DNA, chloroplast ribosomes, thylakoid system, starch granules, and other protein are found floating around the stroma. The thylakoid system is suspended in the stroma. It is a collection of membranous sacks called thylakoids. Thylakoids are small sacks that are interconnected. The membranes of these thylakoids are the sites for the light reactions of the photosynthesis to take place. The chlorophyll is found in the thylakoids. The thylakoids are arranged in stacks known as grana. Each granum contains around 10-20 thylakoids.