CORNEAL SURGERY
1. Penetrating keratoplasty
2. Keratoprosthesis
3. Refractive surgery
• Radial keratotomy
• Photorefractive keratectomy (PRK)
• Laser in-situ keratomileusis (LASIK)
• Non-contact laser thermal keratoplasty
Penetrating Keratoplasty
1. Indications
• Optical (e.g. bullous keratopathy, dystrophies)
• Tectonic (e.g. severe stromal thinning, descemetocele)
• Therapeutic (e.g. severe keratitis)
• Cosmetic
• Severe stromal vascularization
• Absence of corneal sensation
• Progressive conjunctival inflammation (e.g. pemphigoid)
• Tear film dysfunction
• Glaucoma
2. Adverse prognostic factors
Technique of penetrating keratoplasty
Excision of donor tissue
a, b - Excision of host tissue
c - Fixation of donor tissue
Signs of late graft rejection
Epithelial
• Intensive topical and periocular steroids
• Occasionally systemic steroids
Endothelial
Treatment
Iritis and inflammation at
graft-host junction
Endothelial precipitates
(Khodadoust line)
Linear epithelial opacity Subepithelial opacities
Keratoprosthesis
Indications
Bilateral blindness from ocular
pemphigoid, chemical burns or
repeated graft failure
Insertion of artificial lenticule into
corneal stroma
• Glaucoma
Main complications
• Retrolenticular membrane formation
Technique
Radial keratotomy
Main indications
• Stable myopia of up to 8D
• Otherwise normal cornea
• Accidental perforation
• Intrastromal epithelial cysts
Main complications
• Decreases myopia by flattening cornea
• Deep incisions from edge of optical zone to limbus
Photorefractive keratectomy ( PRK )
Indications
• Stable myopia up to 6D with astigmatism no more than 3D
• Hypermetropia up to 2.5D
Main complication
Subepithelial haze which
usually resolves after 1-6
months
Reshaping of cornea by excimer laser ablation of
Bowman layer and anterior stroma
Technique
Laser in-situ keratomileusis (LASIK)
Indications - similar to PRK but corrects higher degrees of myopia
• Thin flap of cornea fashioned
• Bed treated with excimer laser
• Flap repositioned
Complications
• Wrinkles in flap
• Cellular interface proliferation
Technique
Non-contact laser thermal keratoplasty
Indications
• Patients over 40 years with hypermetropia up to 2D
• Following overcorrection of myopia
• Corneal curvature is steepened by application
of laser heat to stroma
• Holmium laser spots applied to mid-cornea
Non-contact laser thermal keratoplasty
Indications
• Patients over 40 years with hypermetropia up to 2D
• Following overcorrection of myopia
• Corneal curvature is steepened by application
of laser heat to stroma
• Holmium laser spots applied to mid-cornea

20 corneal surgery

  • 1.
    CORNEAL SURGERY 1. Penetratingkeratoplasty 2. Keratoprosthesis 3. Refractive surgery • Radial keratotomy • Photorefractive keratectomy (PRK) • Laser in-situ keratomileusis (LASIK) • Non-contact laser thermal keratoplasty
  • 2.
    Penetrating Keratoplasty 1. Indications •Optical (e.g. bullous keratopathy, dystrophies) • Tectonic (e.g. severe stromal thinning, descemetocele) • Therapeutic (e.g. severe keratitis) • Cosmetic • Severe stromal vascularization • Absence of corneal sensation • Progressive conjunctival inflammation (e.g. pemphigoid) • Tear film dysfunction • Glaucoma 2. Adverse prognostic factors
  • 3.
    Technique of penetratingkeratoplasty Excision of donor tissue a, b - Excision of host tissue c - Fixation of donor tissue
  • 4.
    Signs of lategraft rejection Epithelial • Intensive topical and periocular steroids • Occasionally systemic steroids Endothelial Treatment Iritis and inflammation at graft-host junction Endothelial precipitates (Khodadoust line) Linear epithelial opacity Subepithelial opacities
  • 5.
    Keratoprosthesis Indications Bilateral blindness fromocular pemphigoid, chemical burns or repeated graft failure Insertion of artificial lenticule into corneal stroma • Glaucoma Main complications • Retrolenticular membrane formation Technique
  • 6.
    Radial keratotomy Main indications •Stable myopia of up to 8D • Otherwise normal cornea • Accidental perforation • Intrastromal epithelial cysts Main complications • Decreases myopia by flattening cornea • Deep incisions from edge of optical zone to limbus
  • 7.
    Photorefractive keratectomy (PRK ) Indications • Stable myopia up to 6D with astigmatism no more than 3D • Hypermetropia up to 2.5D Main complication Subepithelial haze which usually resolves after 1-6 months Reshaping of cornea by excimer laser ablation of Bowman layer and anterior stroma Technique
  • 8.
    Laser in-situ keratomileusis(LASIK) Indications - similar to PRK but corrects higher degrees of myopia • Thin flap of cornea fashioned • Bed treated with excimer laser • Flap repositioned Complications • Wrinkles in flap • Cellular interface proliferation Technique
  • 9.
    Non-contact laser thermalkeratoplasty Indications • Patients over 40 years with hypermetropia up to 2D • Following overcorrection of myopia • Corneal curvature is steepened by application of laser heat to stroma • Holmium laser spots applied to mid-cornea
  • 10.
    Non-contact laser thermalkeratoplasty Indications • Patients over 40 years with hypermetropia up to 2D • Following overcorrection of myopia • Corneal curvature is steepened by application of laser heat to stroma • Holmium laser spots applied to mid-cornea