Critical Care in the 21st century discusses the landscape of critical care and key requirements for information technology to support clinicians in the intensive care unit (ICU). There is increasing demand for critical care but limited resources. Key requirements for IT include providing a complete patient record with all clinical data integrated in one system, effective displays of data and trends, clinical decision support tools, and reliable access anywhere. The best systems will be easy to use and remain running smoothly in the background without interruption.