RADIAL ARTERY ACUTE INJURY
AFTER PCI ASSESSED BY OPTICAL
COHERENCE TOMOGRAPHY
Kanovsky J., Poloczek M., Bocek O., Miklik R., Jerabek P., Ondrus T., Spinar J., Kala
P.
Department of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech
Republic



AimRADIAL2013, New York
Disclosure: Jan Kanovsky, MD, PhD



Dr. Jan Kanovsky has no relevant financial interests to disclose

AimRADIAL2013, New York
Background
Importance of RA condition


The number of transradial coronary catheterizations and
interventions is increasing



The quality of the radial artery (RA) is crucial if used for the
coronary artery bypass graft (CABG)



The number of patients with more than one arterial conduit used
for the CABG is increasing



RA native disease is a predictor of coronary thin-cap
fibroatheroma (TCFA)1
1

Di Vito, 2013

AimRADIAL2013, New York
Background
OCT
 Optical coherence

tomography (OCT) is
intravascular imaging
method with the highest
resolution available (up to
10um)

 OCT of RA can provide

detailed information about
acute injury or chronic
changes of the vessel after
transradial catheterization1
1

Yonetsu, 2010

AimRADIAL2013, New York
TD-OCT study (Yonetsu, 2009)

 High number of

intimal tears and
medial dissections

 Using 16cm sheath,

for imaging pulled
14cm out

 Most of the injuries

in the distal segment

1

Yonetsu, 2010
AimRADIAL2013, New York
Methods



40 consecutive patients admitted for coronary angiography (CAG)
due to non-STEMI diagnosis



First myocardial lesion in patients’s history



First transradial CAG



Informed consent

Exclusion: STEMI, previous MI, acute heart failure, left main
disease, renal insufficiency
AimRADIAL2013, New York
Methods



6F 7cm sheath



Pulled back of 3cm, guiding
catheter moved back into the
sheath



FD-OCT recording of RA,
starting 8cm from the sheath tip
(using X-ray contrast ruler)



Manual injection of the 100%
contrast fluid

AimRADIAL2013, New York
Results

 Only two minor injuries found (5%)
 Few patients with abnormal vessel wall structure (5pts,

12,5%, intimal thickening, calcifications, qualitative
assessment)
 No thrombotic mass found
 All patient asymptomatic

AimRADIAL2013, New York
Injuries

 Intimal tear

AimRADIAL2013, New York
Injuries

 Dissection

AimRADIAL2013, New York
Discussion



In most of the patients
(95%), we found no acute
injury and normal vessel
structure



Major difference in results
comparing to the Yonetsu
study from 2010



Two main differences –
sheath length, TD vs FD
OCT imaging

AimRADIAL2013, New York
Conclusion

 Transradial CAG and intervention is a safe access route,

with minor incidence of acute injuries
 The length of sheath is likely important for the incidence of

RA injury
 Chronic changes are the subject of further research in the

project (all patients scheduled for 9 months follow-up CAG
and OCT).

AimRADIAL2013, New York
Thank you for your attention.



Supported by the Grant of the IGA Ministry of Health of the Czech
Republic no. NT/13830.
AimRADIAL2013, New York

Kanovsky J - AIMRADIAL 2013 - OCT for radial injury

  • 1.
    RADIAL ARTERY ACUTEINJURY AFTER PCI ASSESSED BY OPTICAL COHERENCE TOMOGRAPHY Kanovsky J., Poloczek M., Bocek O., Miklik R., Jerabek P., Ondrus T., Spinar J., Kala P. Department of Internal Medicine and Cardiology, University Hospital Brno, Brno, Czech Republic  AimRADIAL2013, New York
  • 2.
    Disclosure: Jan Kanovsky,MD, PhD  Dr. Jan Kanovsky has no relevant financial interests to disclose AimRADIAL2013, New York
  • 3.
    Background Importance of RAcondition  The number of transradial coronary catheterizations and interventions is increasing  The quality of the radial artery (RA) is crucial if used for the coronary artery bypass graft (CABG)  The number of patients with more than one arterial conduit used for the CABG is increasing  RA native disease is a predictor of coronary thin-cap fibroatheroma (TCFA)1 1 Di Vito, 2013 AimRADIAL2013, New York
  • 4.
    Background OCT  Optical coherence tomography(OCT) is intravascular imaging method with the highest resolution available (up to 10um)  OCT of RA can provide detailed information about acute injury or chronic changes of the vessel after transradial catheterization1 1 Yonetsu, 2010 AimRADIAL2013, New York
  • 5.
    TD-OCT study (Yonetsu,2009)  High number of intimal tears and medial dissections  Using 16cm sheath, for imaging pulled 14cm out  Most of the injuries in the distal segment 1 Yonetsu, 2010 AimRADIAL2013, New York
  • 6.
    Methods  40 consecutive patientsadmitted for coronary angiography (CAG) due to non-STEMI diagnosis  First myocardial lesion in patients’s history  First transradial CAG  Informed consent Exclusion: STEMI, previous MI, acute heart failure, left main disease, renal insufficiency AimRADIAL2013, New York
  • 7.
    Methods  6F 7cm sheath  Pulledback of 3cm, guiding catheter moved back into the sheath  FD-OCT recording of RA, starting 8cm from the sheath tip (using X-ray contrast ruler)  Manual injection of the 100% contrast fluid AimRADIAL2013, New York
  • 8.
    Results  Only twominor injuries found (5%)  Few patients with abnormal vessel wall structure (5pts, 12,5%, intimal thickening, calcifications, qualitative assessment)  No thrombotic mass found  All patient asymptomatic AimRADIAL2013, New York
  • 9.
  • 10.
  • 11.
    Discussion  In most ofthe patients (95%), we found no acute injury and normal vessel structure  Major difference in results comparing to the Yonetsu study from 2010  Two main differences – sheath length, TD vs FD OCT imaging AimRADIAL2013, New York
  • 12.
    Conclusion  Transradial CAGand intervention is a safe access route, with minor incidence of acute injuries  The length of sheath is likely important for the incidence of RA injury  Chronic changes are the subject of further research in the project (all patients scheduled for 9 months follow-up CAG and OCT). AimRADIAL2013, New York
  • 13.
    Thank you foryour attention.  Supported by the Grant of the IGA Ministry of Health of the Czech Republic no. NT/13830. AimRADIAL2013, New York