Django is a Python web framework created in 2003 that encourages rapid development and clean, pragmatic design. It uses a Model-View-Controller architectural pattern with models representing database tables, views containing logic, and templates for user-facing content. Some key features include automatically generated admin interfaces, URL routing, forms handling, internationalization support, and various utilities like static file management. Django is highly customizable and promotes code reuse and modularity through applications that can be combined for a project. It is one of the most popular web frameworks and powers many major sites today.