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Attracting EC Funding - Diana Salmen
The document discusses EU funding opportunities for health research and innovation under Horizon 2020. Horizon 2020 is the EU's 2014-2020 program for research and innovation, with €80 billion allocated. It focuses on three priorities: excellent science, industrial leadership, and societal challenges. In the area of health, challenges include aging populations, disease burden, and pressure on healthcare systems. The goals are to translate science into benefits, improve outcomes, support healthcare sectors, and promote healthy aging. The document provides details on past funding amounts under FP7 and lists several international consortia supported. It outlines the structure and goals of the International Rare Diseases Research Consortium to develop 200 new therapies and means to diagnose rare diseases by 2020.
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Attracting EC Funding - Diana Salmen
- 1. Attracting EC Funding The HumanVariome Project 5th Biennial Meeting 19th-23rd May, 2014 Paris Diana Salmen Innovative and Personalised Medicine Unit Health Research Directorate DG Research & Innovation
- 2. Research and Innovation HORIZON 2020 •The EU’s 2014-20 programme for research & innovation (around € 80 billion) • A core part of Europe 2020, Innovation Union & European Research Area • Three priorities: Excellent science, Industrial leadership, Societal challenges
- 3. Research and Innovation Building onthe FP7 experience…
- 4. Research and Innovation FP7 'Health'– the largest multi-national fund… • …for collaborative research • …to fund excellence • …to bring together scientists • …to tackle global challenges
- 5. Research and Innovation Key figures 6b€ invested to date 1,000 projects 11,000 teams 3,500 organisations 130 countries First outcomes (on 329 closed projects = 1/3 of funded projects) 200 patent applications 9,000 publications 3,3 average SJR* publication 30 spin-offs created * SCImago Journal Ranking
- 6. Research and Innovation International K.O. MouseConsortium International Cancer Genomics Consortium International cooperation: Working on the big challenges International Human Microbiome Consortium Global Research Collaboration for Infectious Disease Preparedness International Rare Diseases Research Consortium International Initiative for Traumatic Brain Injury Research ©rtguest/Fotolia.com Global Alliance for Chronic Diseases International Human Epigenome Consortium
- 7. Research and Innovation International K.O. MouseConsortium International Cancer Genomics Consortium International cooperation: Working on the big challenges International Human Microbiome Consortium Global Research Collaboration for Infectious Disease Preparedness International Rare Diseases Research Consortium International Initiative for Traumatic Brain Injury Research ©rtguest/Fotolia.com Global Alliance for Chronic Diseases International Human Epigenome Consortium
- 8. Research and Innovation www.irdirc.org 200 therapies and meansto diagnose most rare disease by 2020
- 9. Research and Innovation Basic principles •Teams up public and private organisations investing in rare diseases research • Research funders with relevant programmes >$10 million US over a 5-year period can join & work together • Each organisation funds research its own way • Funded projects adhere to a common framework • Agree to share data / standards Alignment – Flexibility - Commitment
- 10. Research and Innovation Executive Committee Chair:Paul Lasko Diagnostics Chair: Kym Boycott Interdisciplinary Chair: Hanns Lochmueller Therapies Chair: Yann Le Cam Scientific Committees Working Groups EU-funded SUPPORT-IRDiRC provides organisational support for Executive and Scientific Committees and Working Groups Coordinator: Prof. Ségolène Aymé, INSERM IRDiRC Governance Structure
- 11. Research and Innovation IRDiRC timelineExploratory Workshop Reykjavik Launch Washington Scientific Committees Working Groups IRDiRC 2013 Conference 3000 diagnostics 50new applications for market authorisation Support- IRDiRC Scientific Secretariat 6000 diagnostics 200 new applications for market authorisation 2010 2011 2012 2013 2015 2020
- 12. Research and Innovation Europe E-RARE 2Consortium (EU) European Commission EURORDIS (EU) Academy of Finland French Muscular Dystrophy Association French National Research Agency French Foundation for Rare Diseases Children's New Hospitals Management Group (GE) German Federal Ministry of Education and research Italian Higher Institute of Health Research Italian Telethon Foundation Lysogene (FR) Netherlands Organisation for Health Research and Development Prosensa (NL) Spanish Carlos III Health Institute UK National Institute for Health Research Committed members © rtguest/Fotolia.com Australia National Health and Medical Research Council Asia BGI (CN) Chinese Rare Disease Consortium Korea National Institute of Health North America Canadian Institutes for Health Research Genome Canada FDA Orphan Products Grants Program Genetic Alliance (US) Genzyme (US) Isis Pharmaceuticals (US) Mendelian Disorders Genome Centres (US NIH) National Centre for Translational Sciences (US NIH) National Cancer Institute (US NIH) National Institute of Neurological Disorders and Stroke (US NIH) National Institute of Arthritis and Musculoskeletal and Skin Diseases (US NIH) National Institute of Child Health and Human Development (US NIH) National Eye Institute (US NIH) NKT Therapeutics (US) NORD (US) Office of Rare Diseases (US NIH) PTC Therapeutics (US) Sanford Research (US) Shire (US)
- 13. Research and Innovation International K.O. MouseConsortium International Cancer Genomics Consortium International cooperation: Working on the big challenges International Human Microbiome Consortium Global Research Collaboration for Infectious Disease Preparedness International Rare Diseases Research Consortium International Initiative for Traumatic Brain Injury Research ©rtguest/Fotolia.com Global Alliance for Chronic Diseases International Human Epigenome Consortium
- 14. Research and Innovation The InternationalHuman Epigenome Consortium (IHEC) is a global consortium with the primary goal of providing free access to high-resolution reference human epigenome maps for normal and disease cell types to the research community. EU Germany USA JapanKorea Canada http://ihec-epigenomes.org/
- 15. Research and Innovation At aGlance Generate reference maps of human epigenomes for key cellular states relevant to health and disease. Ambitious goal to complete 1000 epigenomes Rapid Data Release, Data Coordination, Archiving Environment Disease Aging Translation into Improved Human Health Mechanism Prevention Diagnosis Therapy
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- 18. Research and Innovation • Challengedriven • Broad topics • Less prescriptive topics • Two-year work programme • Stronger focus on the end users
- 19. Research and Innovation • Simplifiedeligibility criteria • Simpler rules for grants • Transparent funding rates • New SME instrument • Successful project running quicker
- 20. Research and Innovation • Horizon2020 is open • Automatic funding • Member States • Associated countries • Countries in Annex of the WP • Exceptions
- 21. Research and Innovation Horizon 2020 'Health,demographic change and wellbeing'
- 22. Research and Innovation • Ageingpopulation • Increased disease burden • Unsustainable and unequal healthcare systems • Healthcare sector under pressure to reform
- 23. Research and Innovation • Translatingscience to benefit citizens • Improve health outcomes • Support a competitive healthcare sector • Test and demonstrate new healthcare models, approaches and tools • Promote healthy and active ageing
- 24. The Work Programme2014 - 2015 Call for 'co-ordination activities' 16 topics (11 in 2014, 5 in 2015) Call 'personalising health and care' 34 topics (15 in 2014, 17 in 2015, 2 open in both years) + 8 other actions not subject to calls for proposals
- 25. Research & Innovation EU fundingfor health research and innovation 2014-2015
- 26. Research & Innovation Understanding health, ageing& disease Improving health information, data exploitation and providing an evidence base for health policies and regulation Integrated, sustainable, citizen-centered care Innovative treatments and technologies Improving diagnosis Implementing personalized medicine in healthcare settings Effective health promotion, disease prevention, preparedness and screening Advancing active and healthy aging
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