Bronchiectasis is a chronic, irreversible dilation of the bronchi and bronchioles that is separate from COPD. It is caused by airway obstruction, infections, and diffuse airway injury. Common pathogens include adenovirus, influenza virus, and Staphylococcus aureus. Symptoms include a productive cough with sputum, dyspnea, fatigue, weight loss, and crackles or wheezing on exam. Diagnosis involves chest x-ray, CT scan, bronchoscopy, and sputum tests. Treatment consists of airway clearance techniques, antibiotics, bronchodilators, and sometimes surgery.