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Brugia malayi
This document discusses the geographical distribution, life cycle, morphology, clinical manifestations, diagnosis, and treatment of four parasitic helminths: 1. Wuchereria bancrofti, found primarily in Southeast Asia, India, and China. It causes lymphatic filariasis. 2. Mansonella perstans, found in West Africa. It causes asymptomatic infection or mild symptoms. 3. Loa loa, found in West and Central Africa. It causes Calabar swelling and eye worm migration. 4. Onchocerca volvulus, found in tropical Africa. It causes skin and eye lesions leading to blindness. Diagnosis involves finding the parasite, microfilaria
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Brugia malayi
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- 3. Lymphatic tissue of Habitat IH RH upperlimps and mammary gland Mansoni ,Anopheles and Aedes Mokey and cats
- 4. Adult is similarto W. bancrofti but smaller Similar to that of W.bancrofti but differs in Nocturnal periodicity 2a.m-10a.m Size ;200x8micro M Tail end; with nuclei Microfilaria
- 6. G. distribution Habitat DH West Africa especially Cameron Loosesubcutaneous tissue Man IH Chrysops fly RH Monkeys and Rodents
- 8. Morphology A dult Similar to W.bancroftibut smaller (3-6 cm) Simple head with no lips The cuticle is covered with small posses except at head and tail
- 9. Microfilaria •Size;250x8 micro M •Tight sheath •Angularcurves •Tail full of nuclei •Appears in blood in day time
- 10. • • • • Loiasis and calaberswelling Adult worm migrates through conjunctiva ,cornea & subcutaneous connective tissue proving allergic reaction then irritation,itching&creeping sensation Invation CNS encephalitis Arthritis
- 11. • • • • Due to allergicreaction to the worm metabolites Rapid swelling appear for 2-3 days then disappear About 2-3 cm in size Localized,hard,non pitting ,painful swelling observed on the wrists and ankles
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- 13. • • Observation of adult worm,under conjunctivaor over the nose bridge History of calaber swelling
- 14. • • • Demonstration of microfilaria inblood at day time Serological tests Esinophilia
- 15. •Antihistaminc,antibiotics &corticosteroid •Diethyl –carbamazin citrate •Ivermectin •Surgicalremoval of adult worms from the conjunctiva
- 16. •Mass treatment of patient •Controlof Chryysops •Health education
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- 19. •Subcutaneous tissue over bonybrominances •Microfilaria doesnot reach the circulation.they are present in the dermis,subcutaneous nodules,all chamber of the eye and they are non periodic
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- 24. •Onchocerca nodules or tumor •Theskin over the nodules show sever dermatitis and intense itching •The lymph node in femoral triangle is enlarged
- 25. •Due to immunologic responseto microfiraria •River blindness •Keratitis •Iridocyclitis •Blindness •Degeerative changes and optic neuritis
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- 28. •Mass nodulectomy in endemicareas •Elimination of the vectors by application of insecticides in the running water •Mass treatment with Ivermectin