Build your dna model and eat it!

Build your dna model and eat it!

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  MURAT OZTURK AMERICAN COLLEGEof EDUCATION 12/12/2017DNA structure and function Lab Activity by Murat Ozturk
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  DNA BACKGROUND  Whenwe isolate from a cell and stretched out, DNA looks like a twisted ladder. So, in this activity, we are going to build DNA model and we will the shape of DNA which is called a double helix.  The sides of the DNA ladder are called the backbone and the steps (also called rungs) of the ladder are pairs of small chemicals called bases.  There are four types of chemical bases in DNA: Adenine (A), Cytosine (C), Guanine (G), and Thymine (T). They form pairs in very specific ways:  Adenine (A) always pairs with Thymine (T) and  Cytosine (C) always pairs with Guanine (G). 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  BACKGROUND Adenine (A) alwayspairs with Thymine (T) and Cytosine (C) always pairs with Guanine (G). 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  Objective 1:  Wewill describe the fundamental chemistry of living cells and then identify the function of the four major macromolecules (i.e., carbohydrates, proteins, lipids, nucleic acids). 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  Objective 3:  Wewill explain how the structure of DNA is essential to heredity and use a model to describe the structure of DNA.  With the help of the historical events, we will lead to our present understanding of DNA to the cumulative nature of science knowledge and technology 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  What are yousupposed to doing this activity?  First, your task is to use the following materials and procedure to construct an edible model of DNA.  When you are finished, use toothpicks and tape to label one of each of the chemical bases.  Second, we will be able to make strawberry DNA extraction lab experiment after that. 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  MATERIALS  You willneed:  2 pieces of licorice  12 toothpicks  9 pink marshmallows  9 yellow marshmallows  9 green marshmallows  9 orange marshmallows  5 paperclips  Masking Tape 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  Instruction of theDNA Model STEP 1 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  STEP 2  Assembleone side of your DNA molecule 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  STEP 3 and4  Label the backbone 12/12/2017DNA structure and function Lab activity by Murat Ozturk Match the chemical base pairs
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  STEP 5 and6  Step 5: Complete your DNA model. Attach the other backbone so your model looks like a ladder.  Step 6: Twist your DNA model. Carefully twist your DNA molecule so that it looks like a double helix 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  FINAL STEP 12/12/2017DNA structureand function Lab activity by Murat Ozturk Label your model. Make flags to label the parts of your DNA out of paper clips and tape. Label one of each of the following: Adenine, Thymine, Cytosine, Guanine, and Backbone. Make sure your chemical base pairs are correct!
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  CONCLUSION  A moleculeof DNA (Deoxyribonucleic Acid) is composed of two backbones and four types of chemical bases.  The backbone is formed by a chain of alternating phosphates and sugars.  Each sugar molecule in the backbone provides an attachment site for one of the chemical bases.  The four types of chemical bases are: adenine, thymine, cytosine and guanine.  They usually are represented by their first letters: A, T, C and G.  The bases form pairs in a very specific way: A always pairs with T, and C always pairs with G.  A pair of bases is connected by hydrogen bonds. Each base in the pair is also connected to a sugar compound in the DNA backbone. 12/12/2017DNA structure and function Lab activity by Murat Ozturk
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  References  Irobalieva RN,Fogg JM, Catanese DJ, Catanese DJ, Sutthibutpong T, Chen M, Barker AK, Ludtke SJ, Harris SA, Schmid MF, Chiu W, Zechiedrich L (October 2015). "Structural diversity of supercoiled DNA". Nature Communications. 6: 8440. Bibcode:2015NatCo...6E8440I. doi:10.1038/ncomms9440. PMC 4608029 . PMID 26455586. 12/12/2017DNA structure and function Lab activity by Murat Ozturk