This document discusses a 74-year-old female patient with severe hypertension, heart failure, and prior renal failure who was treated with CRRT and vasodilators. Measuring the patient's cardiac output, stroke volume, and systemic vascular resistance revealed that the vasodilator was actually raising her blood pressure by lowering her SVR and increasing her CO. Stopping the vasodilator and CRRT lowered her CO and SVR, reducing her blood pressure. The case demonstrates that identifying abnormalities in CO, SV, and SVR is important for determining the appropriate hypertension treatment, as the relationship between hypertension, heart failure, and renal disease can be complex.