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Erythropoiesis
Erythropoiesis is the process of red blood cell formation. It occurs in the yolk sac in embryos, the liver and spleen in fetuses, and the red bone marrow after birth. Factors that affect erythropoiesis include oxygen supply, the state of hematopoietic organs like the bone marrow and liver, hormones, and diet. Erythropoietin is the key hormone that stimulates erythropoiesis by acting on stem cells in the bone marrow to speed up red blood cell development.
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Definition of erythropoiesis; sites of RBC synthesis: yolk sac, liver, spleen, and red bone marrow.
Factors affecting erythropoiesis include oxygen supply, hemopoietic organ health, hormones, and diet.
Erythropoietin is a key hormone in RBC production; influenced by various physiological factors.
Healthy bone marrow & liver are essential for erythropoiesis; hormonal influences on RBC production.
Essential dietary components for erythropoiesis include proteins, minerals (iron, copper, cobalt), and vitamins.
Types of stem cells involved in erythropoiesis and their commitment to erythroid lineage.
BFU-E and CFU-E progenitor cells lead to the development of erythrocytes; stages of RBC development.
Stages of erythropoiesis with key changes such as cell size reduction, nucleus disappearance, and hemoglobin synthesis.
RBC lifespan, differentiation, maturation phases, and conditions leading to reduced or increased RBC counts.