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Gastric Ulcer
The stomach lies in the left upper quadrant of the abdomen and is a muscular, highly vascular organ that is the first part of the gastrointestinal tract. A gastric ulcer is a break in the normal tissue lining of the stomach and is a type of peptic ulcer. Risk factors for gastric ulcers include H. pylori infection, NSAID use, smoking, alcohol abuse and increasing age. The pathophysiology involves excess acid production in the stomach and decreased protective mechanisms of the gastric mucosa.
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Introduction to gastric ulcers, anatomy of the stomach, and objectives for discussion.
Detailed anatomy and histology, including gastric pits, glands, and the muscular structure.
Definition of ulcers; explanation of gastric ulcers as a type of peptic ulcer.
Location of gastric peptic ulcers predominantly near the stomach's body and antrum interface.
Statistics regarding the prevalence of gastric ulcers per 100,000 population.
Key risk factors for gastric ulcers include NSAIDs, H. pylori infection, smoking, and age.
Pathophysiological mechanisms involving NSAIDs, H. pylori, and epithelial transport.
Sources and references used for the presentation on gastric ulcers.
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Gastric Ulcer
- 1. Gastric Ulcer FATIMAAL-AWADH
- 2. Introduction • T HE S TO M AC H I S T H E F I R S T I N T R A - A B D O M I N A L PA R T O F T H E G A S T R O I N T E S T I N A L T R AC T. • I T I S A M U S C U L A R , H I G H LY VA S C U L A R B AG - S H A P E D O R G A N . • T H E S TO M AC H L I E S I N T H E L E F T UPPER QUADRANT OF THE ABDOMEN.
- 3. Objectives Mention theanatomy and histology of the stomach. Define and display the morphology of gastric ulcer. Mention the risk factors & causes of gastric ulcer. Explain the pathophysiology of gastric ulcer.
- 4. Anatomy of thestomach
- 5. Histology of thestomach Gastric pits Mucosa Gastric glands Muscularis mucosa Blood vessels Sub-mucosa Oblique muscle layer Circular muscle layer Muscularis Longitudinal muscle layer Connective tissue layer Serosa Visceral peritunium
- 6. Ulcers An ulceris a medical condition caused by a break in a bodily membrane. Common forms of ulcers include: Genital Mouth Skin ulcer ulcer ulcer Peptic Venous Ulcerative ulcer ulcer colitis
- 7. Gastric ulcer Abreak in the normal tissue that lines the stomach. A type of peptic ulcers.
- 8. Morphology Gastric peptic ulcers are predominantly located near the interface of the body and antrum.
- 9. Statistics per 100,000inhabitant no data less than 20 20-80 80-140 140-200 more than 200
- 10. Risk Factors Non- Helicobacter Smoking Increasing Alcohol steroidal (H) Pylori age abuse anti- infection inflammat- ory drugs
- 11. Pathophysiology NSAIDs; Cigarette H. Pylori Corticosteroids Alcohol Aspirin abuse smoking
- 12. Pathophysiology Cl K H Na Cl Cl Cl K Na H Cl Cl Cl H K Na Cl Cl
- 13. The increasing acidity Activation
- 14. Pathophysiology Decrease in Epithelial Mucosa HCO3¯ Blood transport secretion secretion flow
- 15.
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- 17. References Clinically Ordinated Anatomy,6th ed. Anatomy of the Pg233,Figure2.37.B. stomach http://www.britannica.com/EBchecked/media/68634/ Histology of the Structures-of-the-human-stomach-The-stomach-has- stomach three-layers http://en.wikipedia.org/wiki/Ulcer Definition and types of ulcer http://ak47boyz90.wordpress.com/2010/09/02/l5- Morphology patho-peptic-ulcer-disease/ http://www.umm.edu/patiented/articles/who_gets_p Risk factors eptic_ulcers_000019_5.htm http://www.histopathology-india.net/PepUlc.htm Pathophysiology
Editor's Notes
- #7 A peptic ulcer is a break in the inner lining of the esophagus, stomach, or duodenum caused by the acidic digestive (peptic) juices.