Definition
Gender dysphoria refersto the
distress that may accompany the
incongruence between one`s
experienced or expressed gender
and one`s assigned gender.
3.
Changes from DSM4
• GID first introduced in 1980 (DSM III).
• DSM-5 replaces the diagnostic name “gender identity disorder”
with “gender dysphoria”.
• In DSM-IV, the chapter “Sexual and Gender Identity Disorders”
included three relatively disparate diagnostic classes: gender
identity disorders, sexual dysfunctions, and paraphilia's.
• Gender dysphoria has its own chapter in DSM-5 and separated
from Sexual dysfunctions and Paraphilic disorders.
• A posttransition specifier has been added because many
individuals, after transition, no longer meet criteria for gender
dysphoria; however, they continue to undergo various
treatments to facilitate life in the desired gender.
Diagnostic Criteria
A. Amarked incongruence between one’s experienced/expressed gender and assigned
gender, of at least 6 months’ duration, as manifested by at least six of the following
(one of which must be Criterion A1):
1. A strong desire to be of the other gender or an insistence that one is the other gen
der (or some alternative gender different from one’s assigned gender).
2. In boys (assigned gender), a strong preference for cross-dressing or simulating fe
male attire: or in girls (assigned gender), a strong preference for wearing only typ
ical
masculine clothing and a strong resistance to the wearing of typical feminine clothing.
3. A strong preference for cross-gender roles in make-believe play or fantasy play.
4. A strong preference for the toys, games, or activities stereotypically used or en
gaged
in by the other gender.
5. A strong preference for playmates of the other gender.
6. In boys (assigned gender), a strong rejection of typically masculine toys, games,
and activities and a strong avoidance of rough-and-tumble play; or in girls (as
signed
gender), a strong rejection of typically feminine toys, games, and activities.
7. A strong dislike of one’s sexual anatomy.
8. A strong desire for the primary and/or secondary sex characteristics that match
one’s experienced gender.
B. The condition is associated with clinically significant distress or impairment in
social, school, or other important areas of functioning.
A. A markedincongruence between one’s experienced/expressed gender and
assigned gender, of at least 6 months’ duration, as manifested by at least two of
the following:
1. A marked incongruence between one’s experienced/expressed gender and pri
mary and/or secondary sex characteristics (or in young adolescents, the antici
pated secondary sex characteristics).
2. A strong desire to be rid of one’s primary and/or secondary sex characteristics
be
cause of a marked incongruence with one’s experienced/expressed gender (or in
young adolescents, a desire to prevent the development of the anticipated second
ary sex characteristics).
3. A strong desire for the primary and/or secondary sex characteristics of the
other gender.
4. A strong desire to be of the other gender (or some alternative gender different
from one’s assigned gender).
5. A strong desire to be treated as the other gender (or some alternative gender dif
ferent from one’s assigned gender).
6. A strong conviction that one has the typical feelings and reactions of the other
gen
der (or some alternative gender different from one’s assigned gender).
B. The condition is associated with clinically significant distress or impairment in
social, occupational or other important areas of functioning.
Diagnostic Criteria
8.
Specifiers
Posttransition
The individual hastransitioned to full-time living in the
desired gender (with or without legalization of gender
change) and has undergone (or is preparing to have) at
least one cross-sex medical procedure or treatment regimen
—namely, regu
lar cross-sex hormone treatment or gender
reassignment surgery confirming the desired gender (e.g.,
penectomy, vaginoplasty in a natal male; mastectomy or
phalloplasty in a natal female).
9.
Prevalence
For natal adult
males
•0.005% -0.014%
For natal adult
females
• 0.002%- 0.003%
•In children
• 2:1 to 4.5:1
•In adolescents
• Close to equivalence
•In adults
• Favors natal males
• 1:1 to 6.1:1
Sex ratios
10.
Causes
• The exactcause of gender dysphoria is unknown and there is much debate
over the possible causes of gender dysphoria.
• Psychiatric and biological causes
• Genetic causes of biological sex
• Hormonal causes
• Rare conditions
• Other causes of gender dysphoria
11.
Psychiatric condition meaninga mental ailment and the disease may not have
origins in the brain alone.
•Development that determines biological sex happens in the mother’s womb.
•Anatomical sex is determined by chromosomes that contain the genes and
DNA.
Androgen insensitivity syndrome (AIS) is when a person who is genetically
male (who has one X and one Y chromosome) is resistant to male hormones
(called androgens). As a result, the person has some or all of the physical traits
of a woman, but the genetic makeup of a man.
•In congenital adrenal hyperplasia (CAH) a female fetus has adrenal
glands (small caps of glands over the kidneys) that produce high level
of male hormones. This causes the genitals to become more male in
appearance and, in some cases, the baby may be thought to be
biologically male when she is born.
• chromosomal abnormalities
• Sometimes defects in normal human bonding and child rearing
12.
Associated Features SupportingDiagnosis
❑When visible signs of puberty develop:
• Boys shave their legs
• Girls bind their breasts
❑Clinically referred adolescents often want:
• Hormone treatment
• Gender reassignment surgery
❑Before GRS are at increased risk for suicidal ideation,
suicide attempts and suicides.
❑Adolescents living in an accepting environment may
openly express the desire to be as the experienced gender.
13.
Development and Course
•Young children are less likely than older children, adolescents and
adults to express extreme and persistent anatomic dysphoria.
• Factors related to distress and impairment also vary with age
(e.g., intense crying).
• In adults such distress reduce by supportive environments and
biomedical treatments.
• Impairments (school refusal, development of depression, anxiety
and substance abuse) may be a consequence of gender dysphoria.
14.
Gender Dysphoria withouta disorder of sex
development
• Onset of cross gender behaviors is usually between ages 2 and 4
years, usually at entry into elementary school.
❑Rates of persistence of gender dysphoria:
• In natal males, ranged from 2.2% to 30%
• In natal females, ranged from 12% to 50%
❑whose gender dysphoria does not persist
• In natal male children, androphilic (sexually attracted to males)
• In natal female children, gynephilic (sexually attracted to
females)
15.
Continue
• In bothadolescent and adult natal males, there are two broad
trajectories for develop
ment of gender dysphoria:
❑ Early-onset gender dysphoria
• starts in childhood and continues into adolescence and
adulthood; or, there is an irregular pe
riod in which the gender
dysphoria stops and these individuals self-identify as gay or
ho
mosexual, followed by recurrence of gender dysphoria.
❑Late-onset gender dysphoria
• occurs around puberty or much later in life. Some of these
individuals report having had a desire to be of the other
gender in childhood that was not expressed verbally to
others. Others do not recall any signs of childhood gender
dysphoria.
16.
Gender Dysphoria inassociation with a
disorder of sex development
• Most individuals have already come to medical
attention at an early age.
• Infertility is quite common for this group.
• Disorders of sex development in general are
frequently associated with gender-atypi
cal
behavior starting in early childhood.
17.
Risk and PrognosticFactors
• Temperamental
• Atypical gender behavior among individuals with early onset gender
dysphoria develops in early preschool age
• Environmental
• Males commonly have older brothers than do males without the condition.
• Late onset GD include habitual fetishistic transvestism developing into
autogynephilia (i.e., sexual arousal associated with the thought or image of
oneself as a woman).
18.
Genetic and physiological
•Increased concordance for transsexualism in
monozygotic compared with dizygotic same-sex
twins, and some degree of heritability of gender
dysphoria.
• Androgen insensitivity syndrome (AIS)
• congenital adrenal hyperplasia (CAH)
• Many individuals with disorder of sex
development and markedly gender atypical
behavior do not develop gender dysphoria.
19.
Culture-Related Diagnostic Issues
•Reported across many countries and cultures.
• Reported in Individuals living in cultures with
institutionalized gender categories other than male or female.
20.
Functional consequences ofGender
Dysphoria
❑Cross gender wishes may develop after the first 2-3 years of
childhood:
• Interfere with daily activities
• Failure to develop peer relationships and lead to isolation and
distress.
• Refuse to attend school
❑In adolescents and adults interferes with daily activities and
relationship difficulties:
• Leading to negative self-concept, unemployment, increased rates
of mental disorder comorbidity
• Access to health services and mental health services may be
hindered by structural barriers.
21.
Case study
Sarah (Bornmale with the given name Lucas)
• Sarah is a 10-year-old self-identified female, although she
was assigned the gender of male at birth. She was referred
to the clinical psychologist after a teacher noticed some
self-injurious behavior. Sarah also told her teacher there
were a few students at the school who had been calling her
names and bullying her on Facebook. Sarah’s parents
noticed their child (born male) by about age three was
insistent she was a girl. Sarah played with stereotypical
female toys, and most of her peers in the daycare were
girls rather than boys. Sarah does not have a disorder of
sex, and therefore no biological/medical treatment is
needed at this time. Sarah and her parents have been
working closely with their pediatrician, who has recently
set them up with a support group for families with
transgendered children. Sarah is also seeing her school
counselor since the self-injury incident, to address
depression and anxiety symptoms.
22.
Case study
A 45-year-oldman, dressed as a woman, requests a prescription for
estrogens and a rapid referral for gender reassignment surgery on the
grounds of self-diagnosed transsexualism. He gives a history of lifelong
cross-dressing, which became sexually exciting at puberty. The sexual
excitement diminished in his 20s, to be replaced by a sense of relaxation
and comfort when in a female role, described as being able to express
his feminine side. He is married, but separated, and has 2 children. The
sexual content of his marriage (never very great) diminished after their
birth. He hid his cross-dressing from his wife until she discovered his
female clothes and assumed that he was having an affair. Although
initially tolerant of his cross-dressing, she became increasingly
dissatisfied as he spent more time in a female role and suggested that
they might live together as sisters. Moving away from his wife and
children, he began to purchase estrogens from the internet. He lived as
a woman for all purposes aside from his work, where nothing was
known of his female life outside. He began to feel increasingly unhappy
in his male work life, feeling that he is only truly himself when living as a
woman.
❑ Nonconformity togender roles:
- An example of nonconforming behavior is a girl
who prefers to dress in boys’ clothes. She may
exhibit behaviors that are more culturally typical of
boys, too.
25.
❑Transvestic disorder:
• Transvesticdisorder occurs in heterosexual (or bisexual) adoles
cent and adult males (rarely in females) for whom cross-dressing
behavior generates sex
ual excitement and causes distress and/or
impairment without drawing their primary gender into question.
It is occasionally accompanied by gender dysphoria.
❑ Body dysmorphic disorder:
• An individual with body dysmorphic disorder focuses on the
alteration or removal of a specific body part because it is
perceived as abnormally formed, not because it represents a
repudiated assigned gender. When an individual's presenta
tion
meets criteria for both gender dysphoria and body dysmorphic
disorder, both diag
noses can be given.
26.
❑ Other clinicalpresentations:
• Some individuals with an emasculinization desire who
develop an alternative, nonmale/nonfemale gender identity
do have a presentation that meets criteria for gender
dysphoria.
• However, some males seek castration and/or penec
tomy for
aesthetic reasons or to remove psychological effects of
androgens without chang
ing male identity; in these cases,
the criteria for gender dysphoria are not met.
❑ Schizophrenia and other psychotic disorders:
• In schizophrenia, there may rarely be delusions of belonging to
some other gender. In the absence of psychotic symptoms, in
sistence by an individual with gender dysphoria that he or she is
of some other gender is not considered a delusion.
• Schizophrenia (or other psychotic disorders) and gender dys
phoria may co-occur.
27.
Comorbidity
• Anxiety anddepressive disorders
• Autism spectrum disorder
•Disruptive and impulse control
28.
Other Specified Gender
Dysphoria302.6 (F64.8)
* This category applies to presentations in which symptoms
characteristic of gender dys
phoria that cause clinically significant
distress or impairment in social, occupational, or other important
areas of functioning predominate but do not meet the full criteria for
gender dys
phoria.
* The other specified gender dysphoria category is used in situations in
which the clinician chooses to communicate the specific reason that
the presentation does not meet the criteria for gender dysphoria. This
is done by recording “other specified gender dys
phoria” followed by
the specific reason (e.g., “brief gender dysphoria”).
●An example of a presentation that can be specified using the “other
specified” desig
nation is the following:
●The current disturbance meets symptom criteria for gender
dysphoria, but the duration is less than 6 months.
29.
Unspecified Gender
Dysphoria 302.6(F64.9)
●This category applies to presentations in which symptoms
characteristic of gender dys
phoria that cause clinically
significant distress or impairment in social, occupational,
or oth
er important areas of functioning predominate but
do not meet the full criteria for gender dysphoria.
●The unspecified gender dysphoria category is used in
situations in which the clinician chooses not to specify
the reason that the criteria are not met for gender dyspho
ria, and includes presentations in which there is
insufficient information to make a more specific
diagnosis.