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Haematocrit
The document defines hematocrit as the volume of red blood cells (RBCs) relative to the total volume of whole blood, expressed as a percentage. It notes there are two methods for measuring hematocrit: the macrohematocrit and microhematocrit methods. Normal hematocrit ranges are provided for men, women, infants/children, and newborns. Factors that can increase or decrease hematocrit levels are outlined, and indications for estimating hematocrit are given as screening for anemia and calculating red blood cell indices.
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Definition of PCV, methods of measurement (Macro/microhematocrit), and its significance.
Description of blood components: plasma (55%), WBC and platelets (<1%), erythrocytes (45%).
Normal hematocrit values by category: Men (40-54%), Women (37-47%), Infants/children (30-43%), Newborns (53-65%).
Factors causing high hematocrit: polycythemia, dehydration, smoking, altitude, etc.
Reasons for low hematocrit: anemia, nutrient deficiencies, bleeding, and pregnancy.
Indications for testing hematocrit, including anemia screening and calculating red cell indices.
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Haematocrit
- 1. Haematocrit / Packedcell volume (PCV) • Def: PCV is the volume of RBC in relation to that of whole blood. • Hematocrit literally means blood separation. • It expressed as the volume of red blood cells per litre of whole blood. • It may be also expressed as %. Dr. SAYID
- 2. Haematocrit / Packedcell volume (PCV) 1. Macrohematocrit method (Wintrobe Method) 2. Microhematocrit method Dr. SAYID
- 3. Components of WholeBlood Withdraw blood and place in tube 1 2 Centrifuge Plasma (55% of whole blood) Formed elements WBC and platelets (<1% of whole blood) Erythrocytes (45% of whole blood) Dr. SAYID
- 4. Haematocrit –Normal value Men 0.40to 0.54 l/l (40 – 54%) Women 0.37 to 0.47 l/l (37 – 47%) Infant/child 0.30 to 0.43 l/l (30 - 43%) Newborn 0.53 to 0.65 l/l (53 - 65%) Dr. SAYID
- 5. High Hematocrit Level Somefactors may cause a rise in hematocrit value such as: • Polycythemia • Heart or kidney problems • Intake of anabolic steroids • Dehydration • Diarehea • Lung problems • Burns • Smoking • High altitudes Dr. SAYID
- 6. Low Hematocrit Levels Lowhemoglobin levels due to: • Anemia • Hemolysis • Nutritional deficiencies • Bleeding • Pregnancy Dr. SAYID
- 7. Indication of Hematocritestimation 1. Screening test for anaemia 2. For calculation of red cell indices Dr. SAYID