HCF 2019 Panel 2: Kerry Nugent

HCF 2019 Panel 2: Kerry Nugent

• 1.
  nicnas.gov.au Slide 1 Panel2: Grouping of substances and how to avoid regrettable substitution
• 2.
  nicnas.gov.au Slide 2 nicnas.gov.au DrKerry Nugent Principal Scientist Existing Chemicals, NICNAS
• 3.
  nicnas.gov.au Slide 3 NICNAS– who we are National Industrial Chemicals Notification and Assessment Scheme ■ statutory scheme to assess risks to human health and the environment ■ administered by the Australian Department of Health New scheme – AICIS (replacing NICNAS) ■ from July 2020, Australian Industrial Chemicals Introduction Scheme (AICIS) ■ more risk-proportionate approach with increased post-market focus 24 May 2019
• 4.
  nicnas.gov.au Slide 4 InventoryMulti-Tiered Assessment and Prioritisation ■ 4155 chemicals assessed at Tier II (summary assessment)  502 assessed singly  Remaining 3655 in 333 groups (2 - 493 chemicals) ■ Range of grouping strategies  deprioritisation  prioritisation  recommendations to risk managers. 24 May 2019
• 5.
  nicnas.gov.au Slide 5 Groupingstrategies ■ Toxicophore similarity ■ Common toxic species (eg esters, salts) ■ Mode of action ■ Physicochemical properties 24 May 2019
• 6.
  nicnas.gov.au Slide 6 Confidencein grouping predictions ■ Grouping rationale as a continuum, with increase in confidence with increased evidence base 24 May 2019 Confidence Consequence Justification Lower Higher Priority setting Warning labels Voluntary actions Commissioning studies Bans Severe restrictions Non-definitive Strong
• 7.
  nicnas.gov.au Slide 7 nicnas.gov.au Thankyou!