This document discusses best practices for identifying and prototyping data science use cases within an organization. It recommends establishing a process that involves identifying potential use cases by capturing key stakeholder input, evaluating their impact and priority, and developing prototypes to validate feasibility. The document emphasizes an iterative agile process for data science projects that balances scientific exploration with delivering tangible results. It also covers operationalizing and scaling successful prototypes by addressing infrastructure, process, and organizational challenges.