Industrial Pharmacy – I Questions.pptx

Industrial Pharmacy – I Questions.pptx

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  Industrial Pharmacy –I (BP502T) Questioners By Ankita Burande Assistant Professor Nagpur College of Pharmacy Nagpur
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  Unit1: Preformulation Studies Questions: (10 x 2 = 20 Marks)  What is Racemization? Give example.  Write the methods to study of solid forms of a substance  What is the need of preformulation studies in pharmaceutical product development?  Write the differences between crystalline and amorphous forms of solid.  Define preformulation studies.  Write the BCS classification of drugs.  What is preformulation study  Define bulk density and write its importance in Pharmacy
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  Unit1: Preformulation Studies Questions: (2 x 10 = 20 Marks)  (a) Discuss about crystallinity of solid substances. (b) Describe the chemical reactions involved in degradation of API  Explain the study of physical characteristics during preformulation Questions : (7 x 5 = 35 Marks)  How flow properties of powders are measured?  Explain polymorphism.  Write a note on polymorphism and its applications.  What is BCS classification? Discuss its importance.
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  Unit 2: Tablets Questions: (10 x 2 = 20 Marks)  Explain friability test for tablets.  Explain the importance of enteric coating of tablet.  Describe the granulation methods for tablet manufacturing.  Classify tablets and give ideal characteristics of tablets.  What are the unofficial tests for evaluation of tablets.  Define Enteric coating and give its advantages.  Define buccal and sublingual tablets.  Enlist various types of coating materials of tablets.  Why coating tablets are required  Classify tablets.  What is Orange peel effect in tablet coating
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  Unit 2: Tablets Questions: (2 x 10 = 20 Marks)  a) Describe the compression cycle for tablet manufacturing. (b) Explain in process quality control tests for tablet compression.  (a) Explain perforated coating pans. (b) Write a brief note on filing of capsules.  Enlist the excipients used in tablet manufacture with examples. Write their role and mechanism of action.  Explain quality control tests of tablets.  (a) Explain about disintegration and dissolution test for tablets. (b) Write in detail about evaluation of containers
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  Unit 2: Tablets Questions: (7 x 5 = 35 Marks)  Discuss the steps involved in sugar coating of tablets  Discuss the tablet additives with examples of each class.  Explain about hardness and friability testing of tablets.  Write a brief note on manufacturing defects in tablet coating.  Explain weight variation test and content uniformity test for capsules  Explain sugar coating of tablets.  Explain defects in tablet coating
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  Unit 2: LiquidOrals Questions : (10 x 2 = 20 Marks)  What are the tests used for detecting type of emulsion  Give formulation of suspension  Define emulsion & suspension Questions : (7 x 5 = 35 Marks)  Describe the evaluation of liquid orals as per pharmacopoeia  Write the differences between flocculated and deflocculated suspensions.  Discuss the method for preparation of emulsion.  Explain formulation considerations of liquid dosage forms.  Write a brief note on filling and packaging of oral liquids.
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  Unit 3: Capsules Questions: (10 x 2 = 20 Marks)  Write the differences between type A and type B gelatin  Outline the steps of manufacturing of hard gelatin capsule SHELL  Write a note on sizes of hard gelatin capsules  Mention different sealing methods for hard gelatin capsules  Define Base adsorption Questions : (2 x 10 = 20 Marks)  Explain in detail about manufacturing of hard gelatin capsules and soft gelatin capsules.  (a) Explain perforated coating pans. (b) Write a brief note on filing of capsules.  Explain the formulation and quantity control tests for hard gelatin or soft gelatin capsules  (a) Write in brief about the manufacture of Aerosols. (b) Explain about the defects in capsules.
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  Unit 3: Capsules Questions: (7 x 5 = 35 Marks)  Describe the manufacturing defects of hard gelatin capsules  Explain weight variation test and content uniformity test for capsules.  Explain method of preparation of hard gelatin capsule shell.  Describe the manufacturing of soft gelatin capsules.
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  Unit 3: Pellets Questions: (10 x 2 = 20 Marks)  Write the advantages of pellets.  Enlist the pelletization techniques  What are pellets? Give advantages of pellets Questions : (7 x 5 = 35 Marks)  Explain in detail about extrusion-spheronization technique  Enlist techniques of pelletization. Explain advantages of pallets over conventional dosage forms.  Write a note on palletization process.  Write in detail about solution layering.  Explain powder and liquid layering methods for pelletization, with a note on equipment used for the same.
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  Unit 4: Parenteralproducts Questions : (10 x 2 = 20 Marks)  Explain the concept of aseptic processing  Plastic bottles are preferred over glass bottles for saline. Justify.  Write the type of glass with their uses for pharmaceutical products  What is isotonicity? Explain its importance for parenteral products.  Write the principle involved in LAL test for injectables  What are Tonicity modifiers  Write the significance of isotonicity in parenterals  What are the vehicles used in the preparation of parenterals?  Classify parenteral with suitable examples.  What are pyrogens?  What is aseptic area?  What are the vehicles used in the preparation of parenterals.  Classify parenteral with suitable example
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  Unit 4: Parenteralproducts Questions : (2 x 10 = 20 Marks)  (a) Describe sterility test procedures as per official books. (b) Discuss formulation considerations for ophthalmic products.  (a) Explain pyrogen test for parenterals. (b) Discuss about the formulation of pharmaceutical aerosols.  Write a note on production facilities required for parenteral preparations.  Give the layout for manufacture of parenteral formulations  Explain formulation and the production of parenterals. Questions : (7 x 5 = 35 Marks)  Elaborate the parenteral additives with their examples.  What are pyrogens? Discuss the pyrogen test for injectables.  Elaborate water attack test USP and powder glass test USP for packaging glass.  Discuss quality control of parenteral products.  Write a note on LAL test & sterility test.  Explain the process of freeze drying.  Write a note on injectable suspensions
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  Unit 4: OphthalmicProducts Questions : (10 x 2 = 20 Marks)  What are the special instructions to be printed on the eye drop container according to drugs and cosmetics act. Questions. (2 x 10 = 20 Marks)  (a) Describe sterility test procedures as per official books. (b) Discuss formulation considerations for ophthalmic products. Questions. (7 x 5 = 35 Marks)  Explain Draize eye test for opthalmics.  Explain sterility test for ophthalmic products.  Write a note on formulation & lebelling of eye drops  Explain quality control tests of eye ointment  ite a note on formulation & lebelling of eye drops
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  Unit 5: Cosmetics: Questions.(10 x 2 = 20 Marks)  Define cosmetics and give classification of cosmetics with examples  List out various ingredients used in tooth paste.  List out various ingredients used in tooth paste  What is the difference between cold cream & Vanishing cream.  How sunscreen products help to protect skin against UV radiation? Questions. (2 x 10 = 20 Marks)  a) Elucidate the manufacturing of lipstick. (b) What are the possible interactions between content and packaging material. Questions. (7 x 5 = 35 Marks)  Discuss the manufacturing, and uses of cold cream and vanishing cream  Describe ingredients for toothpaste manufacturing  Write the formulation of cold cream.  Write a note on formulation of hair dyes.
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  Unit 5: PharmaceuticalAerosols: Questions. (10 x 2 = 20 Marks)  Illustrate the components of aerosol system with the help of neat diagram.  Define Propellant.  What are different types of aerosols? Questions. (2 x 10 = 20 Marks)  (a) Describe the components of aerosol system with the help of a neat diagram. (b) Discuss the types of aerosol system.  a) Explain pyrogen test for parenterals. (b) Discuss about the formulation of pharmaceutical aerosols.  (a) Write in brief about the manufacture of Aerosols. (b) Explain about the defects in capsules.  Explain the formulation and evaluation of aerosols. Questions. (7 x 5 = 35 Marks)  Write a brief note on propellants in Aerosols
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  Unit 5: PackagingMaterial Science Questions. (10 x 2 = 20 Marks)  Write the type of glass with their uses for pharmaceutical products  What are the different materials used for packaging? Questions. (2 x 10 = 20 Marks)  a) Elucidate the manufacturing of lipstick. (b) What are the possible interactions between content and packaging material Questions. (7 x 5 = 35 Marks)  Explain the criteria for selection of packaging materials.  Explain the factors affecting selection of pharmaceutical packaging materials.  Write a note on factors influencing choice of containers