Insulin-Resistance presentation doc.pptx

Insulin-Resistance presentation doc.pptx

• 1.
  Root Causes (whatare their origins) Environment + Epigenome/genes+ Microbiome Beliefs-Emotions-Thoughts-Behaviors Nutrition Movement Interpret-Response to stressors, Environmental toxins Sleep Social Connection Trauma Conflict Management Forgiveness Mindfulness Spirituality-Meaning Light quality-entrainment Social Determinants of Health Core Metabolic Imbalances (what drives them) High Insulin levels Inflammation Gut-Barrier Function/Microbiome Circadian Rhythms- Entrainment Mitochondrial Disruption Chronic stress-Allostatic Load Obesity, Pre-diabetes, Diabetes, HBP, Lipids, Heart Disease, Stroke, Degenerative Neurologic, Depression, Arthritis Alzheimer’s, Cancer, Autoimmunity The Origins of Health Systems Biology
• 2.
  Epigenetics: A futureof possibility
• 3.
  Weight Insulin Insulin Resistance And Inflammation Insulin-Inflammation-Obesity Link • HighGlycemic Carbohydrate-Dense Foods • Processed fats (vegetable oils/hydrogenated) • Sedentary States • Stress Response • Disrupted Sleep • Social isolation • Lack of Meaning in work, love, play • Environmental Toxins e.g. mold biotoxins • Poor quality light • Meal timing
• 4.
  Copyright © 2014American Medical Association. All rights reserved. From: Increasing Adiposity: Consequence or Cause of Overeating? JAMA. 2014;():. doi:10.1001/jama.2014.4133
• 5.
  Lipolysis vs. Lipogenesis
• 6.
  Sugar, Fructose andHigh- Glycemic Processed Grains Oral and Gut Microbiome • Inflammation • Neurotransmitter disruption • Insulin Resistance • Weight and Metabolism • Mitochondria- Oxidative stress • HPA axis –Stress Response High-Quality Plant-Based Carbs • Protection from: • Inflammation • Diabetes • Cancer • Obesity
• 7.
  Poor Quality Carbs Acellularcarbohydrate density Excess Insulin Down-regulation of insulin receptors Insulin Resistance Inflammation • Stress • Sleep disruption • Altered gut-permeability/microbiome • Social isolation • Toxin excess • Sedentary states • VAT VAT Fat storage- lipogenesis Leptin resistance Eat more and do less
• 8.
  Lifestyle/Environment Beliefs/Thoughts Food quality Movement Sleep quality Stressload Trauma Circadian rhythm Love and connection Meaning and purpose Natural light/time outdoors Beliefs-thoughts Socioeconomics Education Epigenetics Gene Expression Microbiome Life Metabolic Health Longevity Health span Resilience Consciousness-Spirituality