This document provides an overview of principles of health IT application in healthcare. It discusses how healthcare is different from other industries due to its life-or-death nature, many stakeholders, and fragmented systems. It then explains how health IT can help address issues like errors, lack of information access, and inefficient processes through functions like computerized provider order entry, electronic health records, and health information exchange. The document also reviews landmark reports on medical errors and the need for healthcare reform using health IT.