Excretory System
The nephron consists of a cup-shaped capsule
containing capillaries and the glomerulus, and a long
renal tube.
Blood flows into the kidney through the renal artery,
which branches into capillaries associated with the
glomerulus.
Arterial pressure causes water and solutes from the
blood to filter into the capsule.
Fluid flows through the proximal tubule, which include
the loop of Henle, and then into the distal tubule. The
distal tubule empties into a collecting duct.
The nephron has three functions:
Glomerular filtration of water and solutes from the
blood.
Tubular reabsorption of water and conserved molecules
back into the blood.
Tubular secretion of ions and other waste products from
surrounding capillaries into the distal tubule.
Nephrons filter 125 ml of body fluid per minute;
filtering the entire body fluid component 16 times each
day. In a 24 hour period nephrons produce 180 liters of
filtrate, of which 178.5 liters are reabsorbed.
The remaining 1.5 liters forms urine.
Urine Production:
Filtration in the glomerulus and nephron capsule.
Reabsorption in the proximal tubule.
Tubular secretion in the Loop of Henle.
Components of The Nephron:
Glomerulus: mechanically filters blood
Bowman's Capsule: mechanically filters blood
Proximal Convoluted Tubule: Reabsorbs 75% of the
water, salts, glucose, and amino acids
Loop of Henle: Countercurrent exchange, which
maintains the concentration gradient
Distal Convoluted Tubule: Tubular secretion of H ions,
potassium, and certain drugs.
Kidney Stones:
In some cases, excess wastes
crystallize as kidney stones.
They grow and can become a painful
irritant that may require surgery or
ultrasound treatments.
Kidneys perform a number of homeostatic functions:
Maintain volume of extracellular fluid
Maintain ionic balance in extracellular fluid
Maintain pH and osmotic concentration of the
extracellular fluid.
Excrete toxic metabolic by-products such as urea,
ammonia, and uric acid.
Hormone Control of Water and Salt
Water reabsorption is controlled by the antidiuretic
hormone (ADH) in negative feedback.
ADH is released from the pituitary gland in the brain.
Dropping levels of fluid in the blood signal the
hypothalamus to cause the pituitary to release ADH into
the blood.
ADH acts to increase water absorption in the kidneys.
This puts more water back in the blood, increasing the
concentration of the urine. When too much fluid is
present in the blood, sensors in the heart signal the
hypothalamus to cause a reduction of the amounts of
ADH in the blood.
Aldosterone, a hormone secreted by the kidneys,
regulates the transfer of sodium from the nephron to the
blood.
When sodium levels in the blood fall, aldosterone is
released into the blood, causing more sodium to pass
from the nephron to the blood. This causes water to flow
into the blood by osmosis.
Renin is released into the blood to control aldosterone.
Disruption of Kidney Function
Infection, environmental toxins such as
mercury, and genetic disease can have
devastating results by causing disruption of
kidney function.
Many kidney problems can be treated by
dialysis, where a machine acts as a kidney.
Kidney transplants are an alternative to
dialysis.
Thank you…
By…VV

Invertebrate and Vertebrate Excretory System.pptx

  • 1.
  • 34.
    The nephron consistsof a cup-shaped capsule containing capillaries and the glomerulus, and a long renal tube. Blood flows into the kidney through the renal artery, which branches into capillaries associated with the glomerulus. Arterial pressure causes water and solutes from the blood to filter into the capsule. Fluid flows through the proximal tubule, which include the loop of Henle, and then into the distal tubule. The distal tubule empties into a collecting duct.
  • 35.
    The nephron hasthree functions: Glomerular filtration of water and solutes from the blood. Tubular reabsorption of water and conserved molecules back into the blood. Tubular secretion of ions and other waste products from surrounding capillaries into the distal tubule. Nephrons filter 125 ml of body fluid per minute; filtering the entire body fluid component 16 times each day. In a 24 hour period nephrons produce 180 liters of filtrate, of which 178.5 liters are reabsorbed. The remaining 1.5 liters forms urine.
  • 37.
    Urine Production: Filtration inthe glomerulus and nephron capsule. Reabsorption in the proximal tubule. Tubular secretion in the Loop of Henle.
  • 38.
    Components of TheNephron: Glomerulus: mechanically filters blood Bowman's Capsule: mechanically filters blood Proximal Convoluted Tubule: Reabsorbs 75% of the water, salts, glucose, and amino acids Loop of Henle: Countercurrent exchange, which maintains the concentration gradient Distal Convoluted Tubule: Tubular secretion of H ions, potassium, and certain drugs.
  • 39.
    Kidney Stones: In somecases, excess wastes crystallize as kidney stones. They grow and can become a painful irritant that may require surgery or ultrasound treatments.
  • 40.
    Kidneys perform anumber of homeostatic functions: Maintain volume of extracellular fluid Maintain ionic balance in extracellular fluid Maintain pH and osmotic concentration of the extracellular fluid. Excrete toxic metabolic by-products such as urea, ammonia, and uric acid.
  • 41.
    Hormone Control ofWater and Salt Water reabsorption is controlled by the antidiuretic hormone (ADH) in negative feedback. ADH is released from the pituitary gland in the brain. Dropping levels of fluid in the blood signal the hypothalamus to cause the pituitary to release ADH into the blood. ADH acts to increase water absorption in the kidneys. This puts more water back in the blood, increasing the concentration of the urine. When too much fluid is present in the blood, sensors in the heart signal the hypothalamus to cause a reduction of the amounts of ADH in the blood.
  • 42.
    Aldosterone, a hormonesecreted by the kidneys, regulates the transfer of sodium from the nephron to the blood. When sodium levels in the blood fall, aldosterone is released into the blood, causing more sodium to pass from the nephron to the blood. This causes water to flow into the blood by osmosis. Renin is released into the blood to control aldosterone.
  • 44.
    Disruption of KidneyFunction Infection, environmental toxins such as mercury, and genetic disease can have devastating results by causing disruption of kidney function. Many kidney problems can be treated by dialysis, where a machine acts as a kidney. Kidney transplants are an alternative to dialysis.
  • 61.