The document proposes a full-duplex cognitive MAC (FDC-MAC) protocol for cognitive radio networks. The protocol consists of two stages: (1) a FD sensing stage where secondary users perform concurrent spectrum sensing and transmission at a controlled power level to mitigate self-interference, and (2) a transmission stage where secondary users transmit at maximum power if the sensing stage indicated an available channel. The document develops a mathematical model to analyze the throughput performance of the FDC-MAC protocol and proves that there exists an optimal sensing time and transmit power configuration to maximize throughput. Extensive simulation results demonstrate significant throughput gains of the FDC-MAC protocol over half-duplex and single-stage full-duplex MAC protocols.