NERVOUS SYSTEM
General organizationof Nervous system
It is that system of body which receives information
from inside and outside the body, processes received
information and transmits impulses to control different
bodily functions and to maintain a constant internal
environment despite extreme changes in external
environment.
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CLASSIFICATION OF
NERVOUS SYSTEM
CENTRAL NS:
a) BRAIN
b) SPINAL CORD
PERIPHERAL NS
CRANIO-SPINAL NERVES:
1. cranial nerves(12 pairs)
2. Spinal nerves (31 pairs)
AUTONOMIC NS:
Sympathetic NS
Parasympathetic NS
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Central Nervous System(CNS)
Contains the nerves of the brain
and spinal cord It is formed by
neurons and supporting cells
called neuroglia.
Function =
coordinating center of
incoming/outgoing information
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Structures ofbrain and spinal cord are arranged in two
layers, namely gray matter and white matter.
Gray matter is formed by nerve cell bodies and the proximal
parts of nerve fibers, arising from nerve cell body.
White matter is formed by remaining parts of nerve fibers.
In brain, white matter is placed in the inner part and gray matter
is placed in the outer part. In spinal cord it is vice versa.
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Brain isfound in the skull & serves as overall control center for the
nervous system
Spinal Cord is surrounded by vertebrae and extends down the back
of the neck, thorax and abdomen
Center of many reflex actions
Provides a link between sensory and motor nerves
Both are enclosed in 3 protective membranes called the meninges
(piamater ,arachnoid mater & dura mater )
Space between meninges contains cerebrospinal fluid which
protects and cushions the CNS
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Peripheral Nervous System(PNS)
All parts of the nervous system lying outside the brain and spinal cord.
The sensory and motor neurons that connect to the CNS
Function = to carry info between organs of the body and the CNS
Humans have
12 pairs of cranial nerves (sensory/motor/mixed) which control the
head, face, neck, shoulders
Except VAGUS nerve – controls internal organs
31 pairs of spinal nerves (mixed) which take impulses to and from
the spinal cord
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PERIPHERAL NERVOUSSYSTEM
It is again divided into two subdivisions:
1. Somatic nervous system
2. Autonomic nervous system
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Somatic NervousSystem
Somatic nervous system is concerned with somatic functions.
It includes the nerves supplying the skeletal muscles.
Somatic nervous system is responsible for muscular activities
and movements of the body
Autonomic Nervous System
Autonomic nervous system is concerned with regulation of
visceral functions. So, it is otherwise called involuntary
nervous system. Autonomic nervous system consists of two
divisions,
1. Sympathetic division
2. parasympathetic division
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NEURON
Structural andfunctional unit of nervous system is called
neuron. A nerve fibre, also called an axon, is a long and
slender projection of nerve cells (or neurons) that carry
electrical impulses away from the nerve cell body
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Parts
Cell body
1.Nucleus
2. Nissl bodies
3. Neurofibrils
4. Mitochondria
5. Golgi appratus
Processes or neurites
1. Axon : carry impulses away from cell body
2. Dendrites: carry impulses towards the cell body
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DEPENDING UPON
STRUCTURE
Basedon structure, nerve fibers are classified into two
types:
i. Myelinated Nerve Fibers
Myelinated nerve fibers are the nerve fibers that are
covered by myelin sheath.
ii. Non-myelinated Nerve Fibers
Non-myelinated nerve fibers are the nerve fibers which are
not covered by myelin sheath
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Erlanger and GasserClassification (Based
on Diameter and Conduction Velocity):
Group A Fibers:
Myelinated: Heavily myelinated, leading to fast conduction
velocity.
Subtypes:
Aα (Ia): Largest diameter, fastest conduction, responsible for
proprioception (muscle spindle afferents) and motor neurons.
Aβ (Ib): Medium diameter, fast conduction, involved in touch,
pressure, and proprioception (Golgi tendon organ afferents).
Aγ: Medium diameter, fast conduction, involved in motor
neurons controlling muscle spindles.
Aδ: Small diameter, moderate conduction, responsible for pain,
temperature, and touch.
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Group BFibers:
Myelinated: Moderately myelinated with smaller diameter
than A fibers, leading to slower conduction than A fibers.
Function: Primarily involved in autonomic functions, such
as visceral sensation and motor control.
Group C Fibers:
Unmyelinated: Smallest diameter, unmyelinated, resulting
in slowest conduction velocity.
Function: Involved in pain, temperature, and autonomic
functions
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Type Diameter (µm)Velocity of
conduction (m/s)
A α 12 - 24 70 – 120
A β 6 - 12 30 – 70
A γ 5 - 6 15 – 30
A δ 2 – 5 12 – 15
B 1 – 2 3 – 10
C < 1.5 0.5 - 2
Classification accordingto function:
1. Sensory neurons
Carry nerve impulses from a receptor to the CNS. Have long
dendrites and short axons
These nerves transmit sensory information from receptors in
the body (like touch, pain, temperature, etc.) to the central
nervous system (brain and spinal cord).Example: Nerves that
carry the sensation of a hot stove to the brain.
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2. Motor neurons
Carry nerve impulses from the CNS to an effector (ex.
muscle or gland). Have short dendrites and long axons
These nerves carry signals from the central nervous
system to muscles and glands, enabling movement and
bodily functions. Example: Nerves that allow you to
move your arm or control your heart rate.
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3. Interneurons
Foundcompletely within the CNS. Provide a link within
the CNS between sensory neurons and motor neurons.
Have short dendrites and long or short axons.
These nerves contain both sensory and motor fibers,
allowing them to transmit both sensory information and
motor commands in the same nerve bundle.
Example: Spinal nerves, which carry both sensory
information from the body and motor commands to the
muscles.
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DEPENDING UPON SECRETION
OFNEUROTRANSMITTER
Depending upon the neurotransmitter substance secreted,
nerve fibers are divided into two types:
i. Adrenergic Nerve Fibers
Adrenergic nerve fibers secrete noradrenaline.
ii. Cholinergic Nerve Fibers
Cholinergic nerve fibers secrete acetylcholine
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Classification accordingto length of axon:
1. Golgi Type I Neurons
Golgi type I neurons have long axons. Cell body of these
neurons is in different parts of central nervous system and their
axons reach the remote peripheral organs.
2. Golgi Type II Neurons
Neurons of this type have short axons. These neurons are
present in cerebral cortex and spinal cord.
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Classification according todistribution:
Nerve fibers can be classified by distribution as somatic
(innervating skeletal muscles and skin) or Visceral
(innervating internal organs)
Somatic: These innervate skeletal muscles and the skin,
controlling voluntary movements and providing sensory
input from the body surface..
Visceral: These innervate internal organs, smooth
muscles, and glands, regulating involuntary functions like
heart rate, digestion, and breathing.
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Classification Depending onorigin:
Nerve fibers can be classified by location into cranial and
spinal nerves, with cranial nerves originating from the
brain and spinal nerves from the spinal.
Cranial Nerves: These nerves originate from the brain and
innervate the head, face, and neck.
Spinal Nerves: These nerves originate from the spinal cord
and innervate the rest of the body.
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Ganglia
Groups ofneuron cell bodies that lie within the PNS
Not included with nerves since nerves only contain axons
and dendrites
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Sensory part ofnervous system
Most activities of the nervous system are initiated by
sensory experience exciting sensory receptors, whether
visual receptors in the eyes, auditory receptors in the
ears, tactile receptors on the surface of the body, or
other kinds of receptors.
This sensory experience can either cause immediate
reaction from the brain, or memory of the experience
can be stored in the brain for minutes, weeks, or years
and determine bodily reactions at some future date.
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Motor Part ofthe Nervous System—Effectors
The most important eventual role of the nervous system is to
control the various bodily activities. This is achieved by
controlling
1. Contraction of appropriate skeletal muscles throughout the
body
(2) Contraction of smooth muscle in the internal organs, and
(3) secretion of active chemical substances by both exocrine and
endocrine glands in many parts of the body.
These activities are collectively called motor functions of the
nervous system, and the muscles and glands are called effectors
because they are the actual anatomical structures that perform
the functions dictated by the nerve signals.
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Processing of Information“Integrative” Function of the
Nervous System
When important sensory information excites the
mind, it is immediately channeled into proper
integrative and motor regions of the brain to cause
desired responses. This channeling and processing
of information is called the integrative function of
the nervous system.
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Storage of Information—Memory
The storage of information is the process we call memory,
and this, is a function of the synapses.
Most storage occurs in the cerebral cortex, but even the
basal regions of the brain and the spinal cord can store small
amounts of information
Information stored as memory can become part of the
processing mechanism used to manage subsequently
sensory input. the brain compares new sensory experiences
with those stored in memory and in this way develops
successful strategies to form a motor output.