NERVOUS SYSTEM
Organization of nervous system
PHYSIOLOGY
LECTURE # 7
THE NERVOUS SYSTEM
NERVOUS SYSTEM
General organization of Nervous system
 It is that system of body which receives information
from inside and outside the body, processes received
information and transmits impulses to control different
bodily functions and to maintain a constant internal
environment despite extreme changes in external
environment.
CLASSIFICATION OF
NERVOUS SYSTEM
 CENTRAL NS:
a) BRAIN
b) SPINAL CORD
PERIPHERAL NS
CRANIO-SPINAL NERVES:
1. cranial nerves(12 pairs)
2. Spinal nerves (31 pairs)
AUTONOMIC NS:
Sympathetic NS
Parasympathetic NS
Central Nervous System (CNS)
 Contains the nerves of the brain
and spinal cord It is formed by
neurons and supporting cells
called neuroglia.
 Function =
coordinating center of
incoming/outgoing information
 Structures of brain and spinal cord are arranged in two
layers, namely gray matter and white matter.
 Gray matter is formed by nerve cell bodies and the proximal
parts of nerve fibers, arising from nerve cell body.
 White matter is formed by remaining parts of nerve fibers.
In brain, white matter is placed in the inner part and gray matter
is placed in the outer part. In spinal cord it is vice versa.
 Brain is found in the skull & serves as overall control center for the
nervous system
 Spinal Cord is surrounded by vertebrae and extends down the back
of the neck, thorax and abdomen
 Center of many reflex actions
 Provides a link between sensory and motor nerves
 Both are enclosed in 3 protective membranes called the meninges
(piamater ,arachnoid mater & dura mater )
 Space between meninges contains cerebrospinal fluid which
protects and cushions the CNS
Peripheral Nervous System (PNS)
 All parts of the nervous system lying outside the brain and spinal cord.
 The sensory and motor neurons that connect to the CNS
 Function = to carry info between organs of the body and the CNS
 Humans have
 12 pairs of cranial nerves (sensory/motor/mixed) which control the
head, face, neck, shoulders
 Except VAGUS nerve – controls internal organs
 31 pairs of spinal nerves (mixed) which take impulses to and from
the spinal cord
 PERIPHERAL NERVOUS SYSTEM
It is again divided into two subdivisions:
1. Somatic nervous system
2. Autonomic nervous system
 Somatic Nervous System
Somatic nervous system is concerned with somatic functions.
It includes the nerves supplying the skeletal muscles.
Somatic nervous system is responsible for muscular activities
and movements of the body
 Autonomic Nervous System
Autonomic nervous system is concerned with regulation of
visceral functions. So, it is otherwise called involuntary
nervous system. Autonomic nervous system consists of two
divisions,
1. Sympathetic division
2. parasympathetic division
NEURON
 Structural and functional unit of nervous system is called
neuron. A nerve fibre, also called an axon, is a long and
slender projection of nerve cells (or neurons) that carry
electrical impulses away from the nerve cell body
Parts
 Cell body
1. Nucleus
2. Nissl bodies
3. Neurofibrils
4. Mitochondria
5. Golgi appratus
 Processes or neurites
1. Axon : carry impulses away from cell body
2. Dendrites: carry impulses towards the cell body
DEPENDING UPON
STRUCTURE
 Based on structure, nerve fibers are classified into two
types:
i. Myelinated Nerve Fibers
Myelinated nerve fibers are the nerve fibers that are
covered by myelin sheath.
ii. Non-myelinated Nerve Fibers
Non-myelinated nerve fibers are the nerve fibers which are
not covered by myelin sheath
Erlanger and Gasser Classification (Based
on Diameter and Conduction Velocity):
 Group A Fibers:
 Myelinated: Heavily myelinated, leading to fast conduction
velocity.
 Subtypes:
 Aα (Ia): Largest diameter, fastest conduction, responsible for
proprioception (muscle spindle afferents) and motor neurons.
 Aβ (Ib): Medium diameter, fast conduction, involved in touch,
pressure, and proprioception (Golgi tendon organ afferents).
 Aγ: Medium diameter, fast conduction, involved in motor
neurons controlling muscle spindles.
 Aδ: Small diameter, moderate conduction, responsible for pain,
temperature, and touch.
 Group B Fibers:
 Myelinated: Moderately myelinated with smaller diameter
than A fibers, leading to slower conduction than A fibers.
 Function: Primarily involved in autonomic functions, such
as visceral sensation and motor control.
 Group C Fibers:
 Unmyelinated: Smallest diameter, unmyelinated, resulting
in slowest conduction velocity.
 Function: Involved in pain, temperature, and autonomic
functions
Type Diameter (µm) Velocity of
conduction (m/s)
A α 12 - 24 70 – 120
A β 6 - 12 30 – 70
A γ 5 - 6 15 – 30
A δ 2 – 5 12 – 15
B 1 – 2 3 – 10
C < 1.5 0.5 - 2
Classification according to no. of
processes:
 Unipolar
 Bipolar
 multipolar
 Classification according to function:
1. Sensory neurons
 Carry nerve impulses from a receptor to the CNS. Have long
dendrites and short axons
 These nerves transmit sensory information from receptors in
the body (like touch, pain, temperature, etc.) to the central
nervous system (brain and spinal cord).Example: Nerves that
carry the sensation of a hot stove to the brain.
2. Motor neurons
 Carry nerve impulses from the CNS to an effector (ex.
muscle or gland). Have short dendrites and long axons
 These nerves carry signals from the central nervous
system to muscles and glands, enabling movement and
bodily functions. Example: Nerves that allow you to
move your arm or control your heart rate.
3. Interneurons
 Found completely within the CNS. Provide a link within
the CNS between sensory neurons and motor neurons.
Have short dendrites and long or short axons.
 These nerves contain both sensory and motor fibers,
allowing them to transmit both sensory information and
motor commands in the same nerve bundle.
Example: Spinal nerves, which carry both sensory
information from the body and motor commands to the
muscles.
DEPENDING UPON SECRETION
OF NEUROTRANSMITTER
 Depending upon the neurotransmitter substance secreted,
nerve fibers are divided into two types:
i. Adrenergic Nerve Fibers
Adrenergic nerve fibers secrete noradrenaline.
ii. Cholinergic Nerve Fibers
Cholinergic nerve fibers secrete acetylcholine
 Classification according to length of axon:
1. Golgi Type I Neurons
Golgi type I neurons have long axons. Cell body of these
neurons is in different parts of central nervous system and their
axons reach the remote peripheral organs.
2. Golgi Type II Neurons
Neurons of this type have short axons. These neurons are
present in cerebral cortex and spinal cord.
Classification according to distribution:
 Nerve fibers can be classified by distribution as somatic
(innervating skeletal muscles and skin) or Visceral
(innervating internal organs)
 Somatic: These innervate skeletal muscles and the skin,
controlling voluntary movements and providing sensory
input from the body surface..
 Visceral: These innervate internal organs, smooth
muscles, and glands, regulating involuntary functions like
heart rate, digestion, and breathing.
Classification Depending on origin:
 Nerve fibers can be classified by location into cranial and
spinal nerves, with cranial nerves originating from the
brain and spinal nerves from the spinal.
 Cranial Nerves: These nerves originate from the brain and
innervate the head, face, and neck.
 Spinal Nerves: These nerves originate from the spinal cord
and innervate the rest of the body.
Ganglia
 Groups of neuron cell bodies that lie within the PNS
 Not included with nerves since nerves only contain axons
and dendrites
Sensory part of nervous system
 Most activities of the nervous system are initiated by
sensory experience exciting sensory receptors, whether
visual receptors in the eyes, auditory receptors in the
ears, tactile receptors on the surface of the body, or
other kinds of receptors.
 This sensory experience can either cause immediate
reaction from the brain, or memory of the experience
can be stored in the brain for minutes, weeks, or years
and determine bodily reactions at some future date.
Motor Part of the Nervous System—Effectors
 The most important eventual role of the nervous system is to
control the various bodily activities. This is achieved by
controlling
1. Contraction of appropriate skeletal muscles throughout the
body
(2) Contraction of smooth muscle in the internal organs, and
(3) secretion of active chemical substances by both exocrine and
endocrine glands in many parts of the body.
These activities are collectively called motor functions of the
nervous system, and the muscles and glands are called effectors
because they are the actual anatomical structures that perform
the functions dictated by the nerve signals.
Processing of Information “Integrative” Function of the
Nervous System
When important sensory information excites the
mind, it is immediately channeled into proper
integrative and motor regions of the brain to cause
desired responses. This channeling and processing
of information is called the integrative function of
the nervous system.
Storage of Information—Memory
 The storage of information is the process we call memory,
and this, is a function of the synapses.
 Most storage occurs in the cerebral cortex, but even the
basal regions of the brain and the spinal cord can store small
amounts of information
 Information stored as memory can become part of the
processing mechanism used to manage subsequently
sensory input. the brain compares new sensory experiences
with those stored in memory and in this way develops
successful strategies to form a motor output.

Lecture# 7 Organization of NS.pptx for physical therapy

  • 1.
  • 2.
  • 3.
    NERVOUS SYSTEM General organizationof Nervous system  It is that system of body which receives information from inside and outside the body, processes received information and transmits impulses to control different bodily functions and to maintain a constant internal environment despite extreme changes in external environment.
  • 5.
    CLASSIFICATION OF NERVOUS SYSTEM CENTRAL NS: a) BRAIN b) SPINAL CORD PERIPHERAL NS CRANIO-SPINAL NERVES: 1. cranial nerves(12 pairs) 2. Spinal nerves (31 pairs) AUTONOMIC NS: Sympathetic NS Parasympathetic NS
  • 6.
    Central Nervous System(CNS)  Contains the nerves of the brain and spinal cord It is formed by neurons and supporting cells called neuroglia.  Function = coordinating center of incoming/outgoing information
  • 7.
     Structures ofbrain and spinal cord are arranged in two layers, namely gray matter and white matter.  Gray matter is formed by nerve cell bodies and the proximal parts of nerve fibers, arising from nerve cell body.  White matter is formed by remaining parts of nerve fibers. In brain, white matter is placed in the inner part and gray matter is placed in the outer part. In spinal cord it is vice versa.
  • 8.
     Brain isfound in the skull & serves as overall control center for the nervous system  Spinal Cord is surrounded by vertebrae and extends down the back of the neck, thorax and abdomen  Center of many reflex actions  Provides a link between sensory and motor nerves  Both are enclosed in 3 protective membranes called the meninges (piamater ,arachnoid mater & dura mater )  Space between meninges contains cerebrospinal fluid which protects and cushions the CNS
  • 9.
    Peripheral Nervous System(PNS)  All parts of the nervous system lying outside the brain and spinal cord.  The sensory and motor neurons that connect to the CNS  Function = to carry info between organs of the body and the CNS  Humans have  12 pairs of cranial nerves (sensory/motor/mixed) which control the head, face, neck, shoulders  Except VAGUS nerve – controls internal organs  31 pairs of spinal nerves (mixed) which take impulses to and from the spinal cord
  • 10.
     PERIPHERAL NERVOUSSYSTEM It is again divided into two subdivisions: 1. Somatic nervous system 2. Autonomic nervous system
  • 11.
     Somatic NervousSystem Somatic nervous system is concerned with somatic functions. It includes the nerves supplying the skeletal muscles. Somatic nervous system is responsible for muscular activities and movements of the body  Autonomic Nervous System Autonomic nervous system is concerned with regulation of visceral functions. So, it is otherwise called involuntary nervous system. Autonomic nervous system consists of two divisions, 1. Sympathetic division 2. parasympathetic division
  • 12.
    NEURON  Structural andfunctional unit of nervous system is called neuron. A nerve fibre, also called an axon, is a long and slender projection of nerve cells (or neurons) that carry electrical impulses away from the nerve cell body
  • 13.
    Parts  Cell body 1.Nucleus 2. Nissl bodies 3. Neurofibrils 4. Mitochondria 5. Golgi appratus  Processes or neurites 1. Axon : carry impulses away from cell body 2. Dendrites: carry impulses towards the cell body
  • 14.
    DEPENDING UPON STRUCTURE  Basedon structure, nerve fibers are classified into two types: i. Myelinated Nerve Fibers Myelinated nerve fibers are the nerve fibers that are covered by myelin sheath. ii. Non-myelinated Nerve Fibers Non-myelinated nerve fibers are the nerve fibers which are not covered by myelin sheath
  • 15.
    Erlanger and GasserClassification (Based on Diameter and Conduction Velocity):  Group A Fibers:  Myelinated: Heavily myelinated, leading to fast conduction velocity.  Subtypes:  Aα (Ia): Largest diameter, fastest conduction, responsible for proprioception (muscle spindle afferents) and motor neurons.  Aβ (Ib): Medium diameter, fast conduction, involved in touch, pressure, and proprioception (Golgi tendon organ afferents).  Aγ: Medium diameter, fast conduction, involved in motor neurons controlling muscle spindles.  Aδ: Small diameter, moderate conduction, responsible for pain, temperature, and touch.
  • 16.
     Group BFibers:  Myelinated: Moderately myelinated with smaller diameter than A fibers, leading to slower conduction than A fibers.  Function: Primarily involved in autonomic functions, such as visceral sensation and motor control.  Group C Fibers:  Unmyelinated: Smallest diameter, unmyelinated, resulting in slowest conduction velocity.  Function: Involved in pain, temperature, and autonomic functions
  • 17.
    Type Diameter (µm)Velocity of conduction (m/s) A α 12 - 24 70 – 120 A β 6 - 12 30 – 70 A γ 5 - 6 15 – 30 A δ 2 – 5 12 – 15 B 1 – 2 3 – 10 C < 1.5 0.5 - 2
  • 18.
    Classification according tono. of processes:  Unipolar  Bipolar  multipolar
  • 19.
     Classification accordingto function: 1. Sensory neurons  Carry nerve impulses from a receptor to the CNS. Have long dendrites and short axons  These nerves transmit sensory information from receptors in the body (like touch, pain, temperature, etc.) to the central nervous system (brain and spinal cord).Example: Nerves that carry the sensation of a hot stove to the brain.
  • 20.
    2. Motor neurons Carry nerve impulses from the CNS to an effector (ex. muscle or gland). Have short dendrites and long axons  These nerves carry signals from the central nervous system to muscles and glands, enabling movement and bodily functions. Example: Nerves that allow you to move your arm or control your heart rate.
  • 21.
    3. Interneurons  Foundcompletely within the CNS. Provide a link within the CNS between sensory neurons and motor neurons. Have short dendrites and long or short axons.  These nerves contain both sensory and motor fibers, allowing them to transmit both sensory information and motor commands in the same nerve bundle. Example: Spinal nerves, which carry both sensory information from the body and motor commands to the muscles.
  • 23.
    DEPENDING UPON SECRETION OFNEUROTRANSMITTER  Depending upon the neurotransmitter substance secreted, nerve fibers are divided into two types: i. Adrenergic Nerve Fibers Adrenergic nerve fibers secrete noradrenaline. ii. Cholinergic Nerve Fibers Cholinergic nerve fibers secrete acetylcholine
  • 24.
     Classification accordingto length of axon: 1. Golgi Type I Neurons Golgi type I neurons have long axons. Cell body of these neurons is in different parts of central nervous system and their axons reach the remote peripheral organs. 2. Golgi Type II Neurons Neurons of this type have short axons. These neurons are present in cerebral cortex and spinal cord.
  • 25.
    Classification according todistribution:  Nerve fibers can be classified by distribution as somatic (innervating skeletal muscles and skin) or Visceral (innervating internal organs)  Somatic: These innervate skeletal muscles and the skin, controlling voluntary movements and providing sensory input from the body surface..  Visceral: These innervate internal organs, smooth muscles, and glands, regulating involuntary functions like heart rate, digestion, and breathing.
  • 26.
    Classification Depending onorigin:  Nerve fibers can be classified by location into cranial and spinal nerves, with cranial nerves originating from the brain and spinal nerves from the spinal.  Cranial Nerves: These nerves originate from the brain and innervate the head, face, and neck.  Spinal Nerves: These nerves originate from the spinal cord and innervate the rest of the body.
  • 27.
    Ganglia  Groups ofneuron cell bodies that lie within the PNS  Not included with nerves since nerves only contain axons and dendrites
  • 28.
    Sensory part ofnervous system  Most activities of the nervous system are initiated by sensory experience exciting sensory receptors, whether visual receptors in the eyes, auditory receptors in the ears, tactile receptors on the surface of the body, or other kinds of receptors.  This sensory experience can either cause immediate reaction from the brain, or memory of the experience can be stored in the brain for minutes, weeks, or years and determine bodily reactions at some future date.
  • 29.
    Motor Part ofthe Nervous System—Effectors  The most important eventual role of the nervous system is to control the various bodily activities. This is achieved by controlling 1. Contraction of appropriate skeletal muscles throughout the body (2) Contraction of smooth muscle in the internal organs, and (3) secretion of active chemical substances by both exocrine and endocrine glands in many parts of the body. These activities are collectively called motor functions of the nervous system, and the muscles and glands are called effectors because they are the actual anatomical structures that perform the functions dictated by the nerve signals.
  • 30.
    Processing of Information“Integrative” Function of the Nervous System When important sensory information excites the mind, it is immediately channeled into proper integrative and motor regions of the brain to cause desired responses. This channeling and processing of information is called the integrative function of the nervous system.
  • 31.
    Storage of Information—Memory The storage of information is the process we call memory, and this, is a function of the synapses.  Most storage occurs in the cerebral cortex, but even the basal regions of the brain and the spinal cord can store small amounts of information  Information stored as memory can become part of the processing mechanism used to manage subsequently sensory input. the brain compares new sensory experiences with those stored in memory and in this way develops successful strategies to form a motor output.