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Management of Pandemic| November 19, 2020| Analysis

This document provides an overview and updates on the global race to develop vaccines and testing for COVID-19. It profiles several key companies involved in vaccine development, including CanSino Biologics, Symvivo Corporation, Novavax, CureVac, Generex, Vaxart, Medicago, and Altimmune. It also discusses companies involved in testing, treatment options like antibodies, and global testing market trends. Major funding sources like the Bill and Melinda Gates Foundation and governments are supporting many of these efforts. Additional research is still needed but progress is being made on vaccines, testing, and treatments.

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RACE TO COVID19 VACCINE AND TESTING PAUL YOUNG CPA CGA NOVEMBER 19, 2020
PAUL YOUNG - BIO • CPA, CGA • Academia (PF1, FA4 and MS2) • SME – Risk Management • SME – Close, Consolidate and Reporting • SME – Public Policy • SME – Emerging Technology • SME – Business Process Change • SME – Financial Solutions • SME – Supply Chain Management Contact information: Paul_Young_CGA@Hotmail.com
INTRODUCTION This presentation looks at what is happening with the COVID19 vaccine development.
AGENDA  Pharma and Vaccines development  Key Companies  CANSINO BIOLOGICS  Symvivio Corporation  Novovax  CureVac  Generex  Vaxart  Medicago  Takis  Altimmune  Testing  Testing Kits  Global Market / Testing  Effective Treatments • Antibodies • Mitigation • Contact Tracing • Medical Equipment and Supplies • Justin Trudeau Management • Donald Trump and Pandemic • WHO • CDC and Deaths • Canada Monitoring • Lockdowns • Variations of Coronaviruses • Travel • Fiscal Management/Canada • Reforming Healthcare • GDP • Cases/Deaths • Storage • Summary
MAJOR PLAYERS / VACCINES DEVELOPMENT
FINANCIAL PERFORMANCE KEY COMPANIES
CANSINO BIOLOGICS INC.(6185)  100% of the revenue is in China - https://www.marketscreener.com/CANSINO-BIOLOGICS-INC- 59318312/company/  The chair is McGill graduate. https://www.marketscreener.com/business- leaders/Xue-Feng-Yu-0DD2L9-E/biography/ Trudeau attended McGill and McGill has high Chinese enrolment - https://www.mcgill.ca/international/channels/news/mcgill-news-china- tops-international-enrolment-mcgill-first-time-291377  J&J and Casino have similar vaccine - https://www.reuters.com/article/health-coronavirus-vaccine/special- report-countries-companies-risk-billions-in-race-for-coronavirus- vaccine-idUSL2N2CF0JG. China is ahead of the curve. China weakness has always been with real facts.  https://www.fiercepharma.com/vaccines/china-s-cansino-pushes- coronavirus-vaccine-into-clinical-testing-as-moderna-doses-1st “The green light was doled out very quickly. It was only Tuesday when CanSino said it had filed the pre-IND review application for the vaccine to authorities and was in the process of a rolling submission of technical documents. CanSino’s candidate, dubbed Ad5-nCoV, uses its adenovirus- based viral vector vaccine platform. In 2017, the same technology helped the company earn a Chinese nod for its Ebola vaccine, which was the first Ebola shot approved anywhere based on the strain behind the deadly epidemic in West Africa in 2014.  Trial of COVID19 drug back by the Military - https://twitter.com/dockaurg/status/1262018934569664515  Last 10K filed was 2017 - https://fintel.io/filings/us/casbf  Only 2018 showed revenue
SYMVIVIO CORPORATION  Early VC company working with Canadian government - https://pitchbook.com/profiles/company/185411-98#funding (Key investor - National Research Council Canada  https://www.dnb.com/business-directory/company- profiles.symvivo_corporation.31108ce6e17eb52f4e64c097dc36f2f7.html “Symvivo Corporation is in Burnaby, BC, Canada and is part of the Biotechnology Research Services Industry. Symvivo Corporation has 3 total employees across all of its locations and generates $580,698 in sales (USD).”  Small venture capital and pre-trials - https://www.trialsitenews.com/ubc- dalhousie-university-commence-study-of-the-bactrl-spike-vaccine-targeting- covid-19/ “According to one profile, the venture has raised $2 million from a local early state venture investor and $100K from a National Research Council. Founder Graves started the company, along with Mark Fox—a friend from undergrad—as he realized “he sucked” at research but desired to leverage his scientific degree in meaningful ways. Graves and Fox sought to develop a platform that could accelerate drug development by focusing on the discovery—developing patents for aspects of the drug delivery process that could be licensed to drug makers”
NOVOVAX  A small group of scientists, execs, and VCs are $277 million richer as their companies race to create a coronavirus vaccine. Here are 7 who have raked in huge sums. - https://markets.businessinsider.com/news/stocks/coronavirus-drugmakers-moderna- gilead-novavax-stock-price-profit-millions-shareholders-2020-2-1028949761  Stock sales due to trials - https://www.bizjournals.com/washington/news/2020/05/20/novavax-prepares-stock- sale-as-covid-19-vaccine.html  https://finance.yahoo.com/news/novavax-nvax-stock-come-too-224659672.html “Vaccine specialist Novavax (NVAX) stepped up to the plate, and hit the ball out of the park yet again. Investors had already enjoyed some pretty hefty gains in 2020 before more positive developments sent the stock into the stratosphere. Last week, news that Novavax had received a $384 million grant from the Coalition for Epidemic Preparedness Innovations (CEPI) to support the development of its COVID-19 vaccine candidate, NVX-CoV2373, resulted in a 133% addition to the share price”  Coalition Preparedness https://cepi.net/about/whoweare/ - CEPI has secured financial investment from the Governments of Australia, Belgium, Canada, Denmark, Ethiopia, Finland, Germany, Japan, the Kingdom of Saudi Arabia, the Netherlands, Norway, the UK and Switzerland, as well as the Bill & Melinda Gates Foundation, and Wellcome. The European Commission provides substantial financial contributions to support relevant projects through its mechanisms. CEPI has also received donations from the private sector and individuals through the UN Foundation’s COVID-19 Solidarity Response Fund to support our COVID-19 vaccine development efforts.
CUREVAC  As the race to develop a coronavirus vaccine intensifies, one player— German drugmaker CureVac—is backed by particularly deep pockets. CureVac, which is in the headlines amid rumors that the U.S. government offered funding to lure its research exclusively to America, counts one of Germany’s richest entrepreneurs, Mexican shopping mall tycoons and the Bill and Melinda Gates Foundation among its investors. https://www.forbes.com/sites/martaorosz/2020/03/16/these-are-the- billionaire-investors-behind-german-drugmakers-developing-a- coronavirus-vaccine/#78c83f841fb8  Regulators / Germany https://www.ft.com/content/7409dbae-6b4f- 4be0-ba75-46ed52e951ae  In the race to find a medical breakthrough to the pandemic, the startup, CureVac, said earlier this month that its proprietary technology has found suitable candidates that could lead to a treatment, and that it aims to start clinical trials in early summer. CureVac has received funding from the Bill & Melinda Gates Foundation. - https://fortune.com/2020/03/16/coronavirus-cure- trump-businesses-biotech/
GENEREX  Manufacturing of peptide - https://www.globenewswire.com/news- release/2020/05/04/2026744/0/en/Generex-Biotechnology- Initiates-Peptide-Manufacturing-for-Ii-Key-SARS-CoV-2-Peptide- Vaccine-Against-the-COVID-19-Pandemic.html  Stock/Generex- https://www.fool.com/investing/2020/05/17/is- buying-a-basket-loaded-with-every-coronavirus-v.aspx “BIO, the biggest trade group representing the biotechnology industry, currently lists 28 companies that are actively involved in developing COVID-19 vaccines. Here are the 21 of those drugmakers that are publicly traded:”
VAXART  SOUTH SAN FRANCISCO, Calif., May 20, 2020 (GLOBE NEWSWIRE) -- Vaxart, Inc. (“Vaxart” or the “Company”) (NASDAQ: VXRT), a clinical- stage biotechnology company developing oral recombinant vaccines that are administered by tablet rather than by injection, today announced that it has selected its lead COVID-19 vaccine candidate and has contracted with KindredBio to manufacture bulk vaccine under cGMP to complement the manufacturing capacity of partner Emergent BioSolutions https://www.globenewswire.com/news- release/2020/05/20/2036357/0/en/Vaxart-Announces-Selection-of- its-Oral-COVID-19-Vaccine-Lead-Candidate.html  Funding issues - https://seekingalpha.com/article/4334623-vaxarts- coronavirus-stock-bump-is-unlikely-to-continue-exit-now-be-long  Cash on hand - https://www.fool.com/investing/2020/04/28/why- vaxart-stock-slumped-today.aspx  Partnerships - https://observer.com/2020/05/covid-19-vaccine- moderna-results-new-progress/
MEDICAGO  Quebec Funding - https://www.canadianmanufacturing.com/research-and- development/government-of-quebec-providing-7m-to- medicagos-covid-19-vaccine-development-249412/  Animal Trials - https://www.sttinfo.fi/tiedote/medicago- announces-positive-results-in-animal-trials-for-its-vaccine- candidate-against-covid- 19?publisherId=58763726&releaseId=69881188  Collaborative project of more than $1.2 million using artificial intelligence to optimize the production of vaccines, announced by CQDM and Medicago R&D - https://www.newswire.ca/news- releases/collaborative-project-of-more-than-1-2-million-using- artificial-intelligence-to-optimize-the-production-of-vaccines- announced-by-cqdm-and-medicago-r-amp-d-859733879.html
TAKIS  “TAKIS SRL is located in ROMA, ROMA, Italy and is part of the Scientific Research & Development Services Industry. TAKIS SRL has 15 employees at this location and generates $1.78 million in sales (USD). There are 4 companies in the TAKIS SRL corporate family. https://www.dnb.com/business-directory/company- profiles.takis_srl.1084976c4f88cf6ddd4089044968c511.html  Startup - https://www.forbes.com/sites/giacomotognini/2020/04/21/inside -the-tiny-italian-biotech-startup-racing-to-develop-a- coronavirus-vaccine/#b686e172c106  Funding - https://finance.yahoo.com/news/applied-dna-takis- biotech-announce-070000273.html
UPDATE – VACCINES / DEVELOPMENT Source - “” https://www.healthline.com/healt h-news/heres-exactly-where- were-at-with-vaccines-and- treatments-for-covid-19
VACCINES DEVELOPMENT  GSK - https://indianexpress.com/article/coronavirus/coronavirus-covid-19-vaccine-glaxosmithkline-oxford- astrazeneca-moderna-clover-status-check-6469474/  Vaccine Tracker - https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html  Gavi organization funding from sources like Bill Gates and world governments - https://www.biopharma- reporter.com/Article/2020/06/17/Gavi-receives-billions-in-funding  Gates and Inovio - https://www.newsbreak.com/missouri/kansas-city/news/0OfXdfSR/a-potential-coronavirus- vaccine-funded-by-bill-gates-is-set-to-begin-testing-in-people-with-the-first-patient-expected-to-get-it- today
ALTIMUNE  “Shares of Altimmune (ALT) - Get Report soared Thursday after the clinical-stage biopharmaceutical company announced the next step in development of its coronavirus vaccine AdCovid. “In collaboration with the University of Alabama at Birmingham, we have commenced preclinical testing of candidates for our Covid- 19 vaccine, AdCovid,” the company said in a statement. https://www.thestreet.com/investing/altimmune-coronavirus- vaccine-preclinical-trial  Former Pfizer board director appointed to Altimmune - https://www.reuters.com/companies/ALT.OQ
TESTING  COVID19 – Testing “It uses a simple assay containing plasmonic gold nanoparticles to detect a color change when the virus is present. The test does not require the use of any advanced laboratory techniques, such as those commonly used to amplify DNA, for analysis. The authors published their work last week in the American Chemical Society’s nanotechnology journal ACS Nano. "Based on our preliminary results, we believe this promising new test may detect RNA material from the virus as early as the first day of infection. Additional studies are needed, however, to confirm whether this is indeed the case,” said study leader Dipanjan Pan, PhD, professor of diagnostic radiology and nuclear medicine and pediatrics at UMSOM.” https://www.umaryland.edu/news/archived-news/may-2020/covid-19- results-in-10-minutes-umb-studies-rapid-test.php or https://www.nextbigfuture.com/2020/05/ten-minute-covid-19- detection-test-using- nanoparticles.html?utm_source=feedburner&utm_medium=feed&utm_ campaign=Feed%3A+blogspot%2Fadvancednano+%28nextbigfuture% 29
TESTING KITS Source - https://www.medtechdive.com/news/coronavirus-tests-home-collection-quest-diagnostics- letsgetchecked/578837/ The cost is $129 per kit!
GLOBAL MARKET / TESTING Source - https://www.globenewswire.com/news-release/2020/06/01/2041269/0/en/Global-COVID-19-diagnostic-testing-market-to-amass-USD-44481-8-million-in-2020.html • Additional costs to already strapped healthcare system • Private insurance companies and their coverage in terms of their testing. This could mean a rise in premiums • Consumers could be out of pocket about $129 per test.
TREATMENT OPTIONS
ANTIBODIES  “Much remains to be learnt about the immunological responses to SARS-CoV-2. Nevertheless, it is becoming clear that antibodies taken from the blood serum of people who have recovered from COVID-19 can be used for treatment by being transfused into other people who have the disease”Source - https://www.nature.com/articles/d41586-020-01816-5  Disappearance of antibodies 2-3 months - https://www.medscape.com/viewarticle/932671  “Those who did not have a bad case of COVID-19 lose antibodies faster. Forty percent of asymptomatic individuals became seronegative and 12.9% of the symptomatic group became negative for IgG in the early convalescent phase. In addition, asymptomatic individuals exhibited lower levels of 18 pro- and anti-inflammatory cytokines. These data suggest that asymptomatic individuals had a weaker immune response to SARS- CoV-2 infection.mThe research, published in Nature Medicine on June 18, highlights the risks of using COVID-19 ‘immunity passports’ and supports the prolonged use of public health interventions such as social distancing and isolating high-risk groups This seems to indicate that our better bet is t-cell-related therapies and vaccines and hygiene and social distancing.  Avoid getting together with larger groups  Stay 6-10 ten feet apart if at all possible  clean your hands every hour  Source - https://www.nextbigfuture.com/2020/06/coronavirus-antibody-immunity-fades-by-70-within-2-3- months.html?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+blogspot%2Fadvancednano+%28nextbigfuture%29
GENE RESEARCH  Genome sequencing - https://globalnews.ca/news/7072424/alberta-researchers-genome-sequence-covid-19/  AI and Genome sequencing - http://www.genomequebec.com/486-en/news-covid-19-unprecedented- research-combining-genomics-and-artificial-intelligenceicial-intelligence/  Blood type and genome - https://directorsblog.nih.gov/2020/06/18/genes-blood-type-tied-to-covid-19-risk- of-severe-disease/
MITIGATION  Shutting down an economy should be last resort  Private sector is driven by cash flow.  The focus should be on infrastructure, getting goods to market, supply chain, advance technology and reforming of government - https://www.slideshare.net/paulyoungcga/canada-gdp-and-economy-truth-and-what-needs-to-change  All levels of government should review their pandemic responses to ensure they have updated their playbook  Annual audits of risk and crisis management should be completed each year - https://www.slideshare.net/paulyoungcga/the-role-of-operational-and- performancebased-auditing-on-government-and-the-private-sector  WHO needs to provide reports on virus threats including what needs to be done to mitigate the spread  https://www.slideshare.net/paulyoungcga/crisis-management-how-best-to-managed-a-crisis  More coordination by the WHO with all government including monthly status calls around threats  Reporting should also be provided on the threats including performance audits of various WHO programs  Mitigating the spread is to ensure healthcare is provided with the necessary equipment - https://www.cdc.gov/coronavirus/2019-ncov/hcp/ppe-strategy/index.html  Sterilization methods of equipment and masks - https://www.inthehammer.com/hamilton-firms-technology-addresses-covid- waste-and-ppe-shortage  Protecting the most vulnerable  Screening at hospitals and long-term care facilities  Restricting the movement of staff between facilities
UPDATE – JUNE 23, 2020 TO JULY 1, 2O20  State of affairs with COVID19 - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines- and-treatments-for-covid-19  Line is forming for the vaccine - https://www.sciencemag.org/news/2020/06/line-forming-covid-19-vaccine-who- should-be-front  You cannot shut down the economy, but all levels of government including the private sector need to take mitigating steps - https://www.slideshare.net/paulyoungcga/transforming-the-economy-postcovid19-canada-and-the-world  China is using the pandemic to make changes with laws for Hong Kong - https://www.cnn.com/2020/07/01/asia/hong-kong-national-security-law-intl-hnk/index.html  USA buys up key drug - https://globalnews.ca/news/7127951/us-remdesivir-supply-coronavirus/  Antibody treatment - https://www.cnn.com/2020/06/26/health/antibody-therapies-covid-19-update- wellness/index.html
VACCINES, HEALTH AND SAFETY AND TESTING UPDATE  USA clinical trials - https://globalnews.ca/news/7178006/us-coronavirus-vaccine-testing/  Human trials in Quebec - https://www.cbc.ca/news/health/human-trials-covid-19-vaccine-candidate-quebec-1.5648648  World and treatment of COVID19 - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and-treatments-for-covid- 19#Antivirals  Vaccines Trials - https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html  Mobile testing kits - https://www.thestar.com/business/2020/07/09/guelph-companys-mobile-covid-19-test-kit-hits-market-and-heads-for- norther-ontario.html  Workplace measures - https://www.ontario.ca/page/develop-your-covid-19-workplace-safety-plan or http://www.worksafesask.ca/covid- 19/conducting-a-hazard-assessment-and-developing-a-safety-plan/  Mobile workers - https://www.carsondesign.com/2017/12/designing-your-office-space-for-the-mobile-workforce/  Vaccines trials - https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html or https://newsinteractives.cbc.ca/coronavirusvaccinetracker/  Government of Canada order doses - https://www.ctvnews.ca/canada/feds-order-supplies-to-give-two-doses-of-covid-19-vaccine-when-it-s- ready-1.5029530  Status of treatments and Vaccines – August 16, 2020 - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and- treatments-for-covid-19#Vaccines  Treatments - https://catsroundtable.com/yale-prof-harvey-risch-hydroxychloroquine-hcq-covid-19/  Vaccines and drugs - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and-treatments-for-covid-19#Other- treatments 
CONTACT TRACING  Development of contact tracing- “Contact tracing is the public health practice of informing people when they've been exposed to a contagious disease. As it has become more widely employed across the U.S., it has also become mired in modern political polarization and conspiracy theories.” - https://www.npr.org/sections/health- shots/2020/07/14/890628203/conspiracy-theories-aside-heres-what-contact-tracers-really-do  Privacy issues with contact tracing  One of the biggest challenges, experts told a congressional panel this week, is dispelling the unease people feel about the government or private companies gaining access to their personal data - https://www.marketwatch.com/story/us-contract-tracing-efforts-on-covid-19-falter-on-privacy- worries-technology-gap-2020-07-09  Data privacy laws like HIPAA, PIPDEA and EUGRP collide with contact tracing - https://www.reuters.com/article/bc-finreg-data-privacy-contact- tracing/data-privacy-laws-collide-with-contact-tracing-efforts-privacy-is-prevailing-idUSKCN24M1NL  There needs to be audits of the application on routine basis - https://priv.gc.ca/en/privacy-topics/health-genetic-and-other-body- information/health-emergencies/rev_covid-app/ . All levels of government can automate the audit process through AI and Analytics - https://www.slideshare.net/paulyoungcga/internal-audit-and-performance-base-auditing
MEDICAL SUPPLIES AND EQUIPMENT  Companies continue to ramped up production of ventilators - https://www.globenewswire.com/news- release/2020/07/22/2065727/0/en/191-Million-Worldwide-Ventilator-Test-Systems-Industry-to-2027-Impact-of- COVID-19-on-the-Market.html  Global Production - https://www.supplychainbrain.com/articles/31024-coronavirus-watch-governments-rush-to- secure-ventilators  Canada medical supplies and equipment  https://www.tpsgc-pwgsc.gc.ca/comm/aic-scr/provisions-supplies-eng.html  There needs to be an audit the readiness of medical supplies and equipment  Liberals  Masks production - https://torontosun.com/news/national/company-awarded-380m-in-contracts-but-fails-to-provide-masks- blacklocks-reporter  Ventilators - https://thepostmillennial.com/contract-awarded-to-former-liberal-mps-company-to-make-10-000-unapproved- ventilators
JUSTIN TRUDEAU AND PANDEMIC MANAGEMENT https://www.ctvnews.ca/health/coronavirus/the-fall-will-be-a-period-of-challenge-in-coronavirus-fight-canada-s-top-doctor-says- 1.5055678?taid=5f2e1fbcd7d51b0001834cab&utm_campaign=trueAnthem%3A+Trending+Content&utm_medium=trueAnthem&utm_sourc e=twitter When is @CPHO_Canada stepping down as Ms. Tam is not up to any challenge when it comes to protecting the healthcare system? 1. Healthcare - https://www.slideshare.net/paulyoungcga/race-for-covid19-vaccines-and-treatments or https://www.slideshare.net/paulyoungcga/reforming-healthcare 2. PPE Supply - https://news.ontario.ca/opo/en/2020/08/ontario-partners-with-federal-government-and-3m-canada-on-new-n95-respirator- manufacturing-facility.html 3. People are still entering Canada from hot spots despite saying the border was closed - https://www150.statcan.gc.ca/t1/tbl1/en/tv.action?pid=2410000301 4. Migrant program and disease management audit - https://www.thestar.com/business/2020/08/20/migrant-worker- program-to-undergo-federal-audit-following-massive-covid-19-outbreaks-on-canadian-farms.html 5. Health Canada and drug issues - https://www.ottawamatters.com/national-news/talks-needed-on-decriminalizing-hard-drugs-to-address- opioid-crisis-tam-says-2657216 6. Quebec and Contract tracing - https://www.halifaxtoday.ca/national-news/quebec-wont-ask-population-to-use-covid-19-contact-tracing- smartphone-app-2663902 - Quebec is concern with privacy issues 7. Funding to Education - https://globalnews.ca/news/7298419/feds-2-billion-school-coronavirus/ - Education is a provincial issue -
DONALD TRUMP AND PANDEMIC  Travel restrictions - https://www.bbc.com/news/world-us-canada-51846923  Pandemic funding - https://home.treasury.gov/policy-issues/cares CARES act was held up by Nancy Pelosi - https://www.foxnews.com/politics/mccarthy-blames-pelosi-wish-list-coronavirus-stimulus-bill  State and local funding - https://www.mckinsey.com/industries/public-and-social-sector/our-insights/us- coronavirus-relief-funds-a-guide-for-state-and-local-governments  Assisted living - https://www.whitehouse.gov/briefings-statements/president-donald-j-trump-is-taking- decisive-action-to-protect-vulnerable-citizens-in-americas-nursing-homes/  Blood treatment - https://globalnews.ca/news/7293522/donald-trump-fda-deep-state-coronavirus-vaccine/
CDC / DEATHS Source - https://local12.com/news/nation-world/cdc-94-of-covid-19-deaths-had-underlying-medical-conditions-coronavirus-centers-for-disease-control or https://www.cdc.gov/nchs/nvss/vsrr/covid_weekly/index.htm?fbclid=IwAR3-wrg3tTKK5-9tOHPGAHWFVO3DfslkJ0KsDEPQpWmPbKtp6EsoVV2Qs1Q or https://nbc25news.com/news/local/cdc-94-of-covid-19-deaths-had-underlying-medical-conditions
HEALTHCARE SURVEILLANCE Source - https://nationalpost.com/news/politics/canada-spent-147m-on-a-public-health-surveillance-system-that-isnt-being-used-during-covid-pandemic/wcm/e14f04a1-5314-4c55-a883- 57eeacd3b3e1/ • This was even a Liberal system brought in by Paul Martin
TRAVEL / CANADA Source - https://www150.statcan.gc.ca/n1/daily-quotidien/200916/dq200916e-cansim-eng.htm
FISCAL MANAGEMENT https://www.bnnbloomberg.ca/federal-deficit-hit-170-5b-through-august-on-emergency-spending-1.1515602 “Speaking to the Montreal Chamber of Commerce this morning, Freeland says the spending may seem enormous, but doing any less would cost the country much more economically. No mentioned of stimulus in many cases was poorly targeted My work https://www.slideshare.net/paulyoungcga/fiscal-management-canada-october-2020
NO LOCKDOWN Source - https://eur04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fsiteproxy.ruqli.workers.dev%3A443%2Fhttps%2Fp.feedblitz.com%2Fr3.asp%3Fl%3D173343217%26f%3D64651%26c%3D0%26u%3D15561131&data=02%7C01%7C%7Cfc632a000624411046bd08d86e72a649%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637380785975473172&sdata=KNql94 1j%2BqzPgI8k2HkpS2avk7%2Ba4y6eb4xjBjZbUy8%3D&reserved=0 • All levels of government need to have risk and crisis management plans - https://www.slideshare.net/paulyoungcga/ how-to-implement-crisis-management- using-data-and-ai • The world needs to have performance audits of all organizations like WHO - https://www.slideshare.net/paulyoungcga/ internal-audit-and-governance-modeling- public-and-private-sector
WHO / TEDROS @DrTedros has history of coverups https://www.theglobeandmail.com/world/article-questions-surfacing-about- history-of-whos-director-tedros-adhanom/ or https://www.orfonline.org/expert-speak/dr-cover-up-tedros-adhanoms- controversial-journey-to-the-who-65493/ The WHO also needs to be reformed - https://www.slideshare.net/paulyoungcga/reforming-both-the-united- nations-and-who
CORONAVIRUSES Source - https://www.cdc.gov/coronavirus/types.html • 229E (1960s) - https://www.atsjournals.org/doi/full/10.1164/rccm.201506- 1239LE • NLG63 – (1960s) - https://www.atsjournals.org/doi/full/10.1164/rccm.201506- 1239LE • OC43 – common cold - https://academic.oup.com/cid/article/36/8/985/449256 • HKU1 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374449/ • SARS and other viruses never shutdown the economy • Global Economy could take years to recovered - https://www.slideshare.net/paulyoungcga/what-is- next-for-the-global-economy-october-2020 • There is job crisis in Canada as well as around the world - https://www.slideshare.net/paulyoungcga/pandem ic-and-covid19-canada-and-the-world • More needs to be done to protect healthcare and those most vulnerable - https://www.slideshare.net/paulyoungcga/how- do-you-fixed-assisted-living
CLINICAL TRIALS – COVID19 VACCINES – OCTOBER 12 TO OCTOBER 19  Canada - https://www.canada.ca/en/health-canada/services/drugs-health-products/covid19-industry/drugs- vaccines-treatments/list-authorized-trials.html  USA - https://www.nih.gov/news-events/news-releases/nih-begins-large-clinical-trial-test-immune-modulators- treatment-covid-19  J&J pause - https://www.jnj.com/our-company/johnson-johnson-temporarily-pauses-all-dosing-in-our-janssen- covid-19-vaccine-candidate-clinical-trials  Vaccines - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and-treatments- for-covid-19  Vaccines (October 31 to November 7, 2020) –  Nature - https://www.nature.com/articles/d41586-020-00502-w  Vaccines - https://www.biopharmadive.com/news/coronavirus-vaccine-pipeline-types/579122/
LATEST – PANDEMIC – COVID19  Vaccines timeline - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and- treatments-for-covid-19#COVID-19-vaccines  Vaccines and world economy - https://www.wsj.com/articles/a-covid-19-vaccine-would-boost-the-global- economy-but-not-all-at-once-11605087345  World Meter - https://www.worldometers.info/coronavirus/  Elon Musk testing both positive and negative for COVID19 https://www.wsj.com/articles/tesla-ceo-elon-musk- says-he-tested-both-positive-and-negative-for-covid-19-11605251724  Testing Kits - https://www.ehstoday.com/health/article/21129419/fda-authorizes-athome-covid19-tests
VACCINES  Pfizer - https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-conclude-phase- 3-study-covid-19-vaccine  Moderna - https://investors.modernatx.com/news-releases/news-release-details/modernas-covid-19-vaccine- candidate-meets-its-primary-efficacy
STORAGE / VACCINES You are asking for more than @CPHO_Canada and @PattyHajdu are willing to give in terms of information 1. Cold Storage - https://ca.finance.yahoo.com/news/cold-chain-throws-cold-water-over-pfizer-vaccine-hopes- 133716649.html 2. Supply/Market - https://www.grandviewresearch.com/industry-analysis/biomedical-refrigerators-and-freezers-market 3. Dry Ice - https://www.marketwatch.com/press-release/global-dry-ice-market-size-in-2020-industry-demand-market- share-trend-industry-news-business-growth-top-key-players-top-countries-analysis-and-outlookshowing-impressive- growth-by-2026-2020-09-03 My work on the pandemic - https://www2.slideshare.net/paulyoungcga/crisis-management-pandemic-covid19 Source - https://globalnews.ca/video/7470702/coronavirus-otoole-questions-trudeau-on-freezer- capacity-for-possible-covid-19-vaccine
LATEST ON COVID19  Vaccine reset - https://www.statnews.com/2020/10/29/it-may-be-time-to-reset-expectations-on-when-well- get-a-covid-19-vaccine/  Latest on vaccines - https://www.nationalgeographic.com/science/health-and-human-body/human- diseases/coronavirus-vaccine-tracker-how-they-work-latest-developments-cvd/  PPE Supply - https://www.modernhealthcare.com/supply-chain/hospitals-say-theyre-better-prepared-ppe- spring-supply-chain-uncertain  Reforming Healthcare - https://www.hfma.org/topics/hfm/2020/november/reimagining-the-healthcare- supply-chain-to-bolster-resilience-an.html
REFORMING HEALTHCARE - DIGITAL HOSPITAL https://www.canadianmanufacturing.com/technology/covid-19-sparks-boom-in-digital-hospitals-with-smart-technologies- improving-quality-of-care-262683/ “COVID-19 sparks boom in digital hospitals with smart technologies, improving quality of care” I have written many blogs on the transformation of healthcare https://www.slideshare.net/paulyoungcga/how-does-the- world-transform-healthcare-238832381
COVID19 WILL HELP TRANSFORM HEALTHCARE  https://www.cfo.com/health-benefits/2020/10/7-ways-covid-19-will-transform-health- care/?utm_campaign=CFODailyAlert&utm_nooverride=1&utm_source=CFO- email&utm_medium=email&utm_content=CFODailyAlert_Wednesday_2020-10-14&utm_term=health-benefits Great Article with focus on the following areas: 1. Rise of Virtual Care 2. New digital approaches to meeting mental health needs 3. More entrepreneurial health care startups 4. Provider consolidation 5. More govt involvement 6. Increase in price sensitivity 7. Easing of regulation My analysis - https://www.slideshare.net/paulyoungcga/how-does-the-world-transform-healthcare-238832381
GLOBAL ECONOMY  Many businesses are more prepared for future geopolitical events. The use of AI and Analytics as part of the close, consolidate, and reporting cycle is helping businesses better manage risk - https://www.slideshare.net/paulyoungcga/understanding-risks-as-part-of-development-risk- management-best-practices  Progressive need to stop pushing the global climate agenda as part of their various countries reset - https://www.slideshare.net/paulyoungcga/clean-technology-and-the-green-economy-what-is-next  There are many risks to the world economy - https://www.imf.org/en/Publications/WEO/Issues/2020/09/30/world-economic-outlook-october- 2020  Businesses are pushing back - https://www.talentcanada.ca/ontario-restaurants-ask-province-to-explain-restrictions-show-covid-19-data/ Other Sources  G7 - https://www.slideshare.net/paulyoungcga/what-is-next-for-g7-countries  Circular Economy - https://www.slideshare.net/paulyoungcga/how-to-best-support-a-circular-economy  Global - https://www.slideshare.net/paulyoungcga/what-is-next-for-the-global-economy-september-2020  Canada GDP / August 2020 - https://www.slideshare.net/paulyoungcga/gdp-canada-august-2020  Macros and Micro Indicators - https://www.slideshare.net/paulyoungcga/liberal-party-of-canada-fiscal-and-economic-scorecard-august-2020- and-september-2020
CASES AND DEATH Source - https://www.nbc.ca/en/rates-and- analysis/economic-analysis.html
WORLD WIDE DEATHS Source - - https://www.nbc.ca/en/rates-and- analysis/economic-analysis.html
STORAGE Vaccines freezing market – 1. Cold Storage - https://ca.finance.yahoo.com/news/cold-chain-throws-cold-water-over-pfizer-vaccine-hopes- 133716649.html 2. Supply/Market - https://www.grandviewresearch.com/industry-analysis/biomedical-refrigerators-and-freezers- market 3. Dry Ice - https://www.marketwatch.com/press-release/global-dry-ice-market-size-in-2020-industry-demand- market-share-trend-industry-news-business-growth-top-key-players-top-countries-analysis-and-outlookshowing- impressive-growth-by-2026-2020-09-03 My work on the pandemic - https://www2.slideshare.net/paulyoungcga/crisis-management-pandemic-covid19
TRAINING AND DEVELOPMENT  If you like to learn more about trade and/or other subjects as part of your professional learning and development then feel free to review my material on https://www.udemy.com/ (search Paul Young CPA CGA)  These subjects address how to fixed issues with housing and/or systemic issues related to economy including government policies
SUMMARY  There are many companies involved with research and development of COVID19 vaccine - https://www.scienceboard.net/index.aspx?sec=sup&sub=imm&pag=dis&ItemID=677  Bill and Melinda Gates Foundation are playing a key role with funding and manufacturing - https://www.geekwire.com/2020/gates-foundation-commits-50m- covid-19-vaccine-initiative-total-funding-now-tops-300m/ (Funding is now over $300M (USD)  There are allot of startups involved. Various Canadian governments have been funding VC companies related to biotech research  There appears to be lack of progress reports on the state of affairs when it comes to government money going to vaccinations R&D - https://cmajnews.com/2020/05/20/coronavirus-1095847/  There is allot of speculator investments going on with biotech companies as part of reaping the rewards when vaccines go to market.  Major pharma continues to work with government, institution, labs, Tech, etc. https://www.bioworld.com/articles/435263-astrazeneca-moving-at-warp-speed-with- 12b-in-barda-funding-for-covid-19-vaccine  Medical Products - https://www.dailymail.co.uk/health/article-8717013/Scarcity-key- material-squeezes-medical-mask-manufacturing.html  Economy could see periods of slow growth for years - https://www.slideshare.net/paulyoungcga/transforming-the-economy-postcovid19- canada-and-the-world or https://www.investmentexecutive.com/news/research-and- markets/covid-19-to-reshape-economy-society-moodys/ or https://www.slideshare.net/paulyoungcga/gdp-canada-may-2020 or https://www.slideshare.net/paulyoungcga/global-economy-current-state-and-whats- next

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Management of Pandemic| November 19, 2020| Analysis

  • 1.
    RACE TO COVID19VACCINE AND TESTING PAUL YOUNG CPA CGA NOVEMBER 19, 2020
  • 2.
    PAUL YOUNG -BIO • CPA, CGA • Academia (PF1, FA4 and MS2) • SME – Risk Management • SME – Close, Consolidate and Reporting • SME – Public Policy • SME – Emerging Technology • SME – Business Process Change • SME – Financial Solutions • SME – Supply Chain Management Contact information: [email protected]
  • 3.
    INTRODUCTION This presentation looksat what is happening with the COVID19 vaccine development.
  • 4.
    AGENDA  Pharma andVaccines development  Key Companies  CANSINO BIOLOGICS  Symvivio Corporation  Novovax  CureVac  Generex  Vaxart  Medicago  Takis  Altimmune  Testing  Testing Kits  Global Market / Testing  Effective Treatments • Antibodies • Mitigation • Contact Tracing • Medical Equipment and Supplies • Justin Trudeau Management • Donald Trump and Pandemic • WHO • CDC and Deaths • Canada Monitoring • Lockdowns • Variations of Coronaviruses • Travel • Fiscal Management/Canada • Reforming Healthcare • GDP • Cases/Deaths • Storage • Summary
  • 5.
    MAJOR PLAYERS /VACCINES DEVELOPMENT
  • 6.
  • 7.
    CANSINO BIOLOGICS INC.(6185)  100% ofthe revenue is in China - https://www.marketscreener.com/CANSINO-BIOLOGICS-INC- 59318312/company/  The chair is McGill graduate. https://www.marketscreener.com/business- leaders/Xue-Feng-Yu-0DD2L9-E/biography/ Trudeau attended McGill and McGill has high Chinese enrolment - https://www.mcgill.ca/international/channels/news/mcgill-news-china- tops-international-enrolment-mcgill-first-time-291377  J&J and Casino have similar vaccine - https://www.reuters.com/article/health-coronavirus-vaccine/special- report-countries-companies-risk-billions-in-race-for-coronavirus- vaccine-idUSL2N2CF0JG. China is ahead of the curve. China weakness has always been with real facts.  https://www.fiercepharma.com/vaccines/china-s-cansino-pushes- coronavirus-vaccine-into-clinical-testing-as-moderna-doses-1st “The green light was doled out very quickly. It was only Tuesday when CanSino said it had filed the pre-IND review application for the vaccine to authorities and was in the process of a rolling submission of technical documents. CanSino’s candidate, dubbed Ad5-nCoV, uses its adenovirus- based viral vector vaccine platform. In 2017, the same technology helped the company earn a Chinese nod for its Ebola vaccine, which was the first Ebola shot approved anywhere based on the strain behind the deadly epidemic in West Africa in 2014.  Trial of COVID19 drug back by the Military - https://twitter.com/dockaurg/status/1262018934569664515  Last 10K filed was 2017 - https://fintel.io/filings/us/casbf  Only 2018 showed revenue
  • 8.
    SYMVIVIO CORPORATION  Early VCcompany working with Canadian government - https://pitchbook.com/profiles/company/185411-98#funding (Key investor - National Research Council Canada  https://www.dnb.com/business-directory/company- profiles.symvivo_corporation.31108ce6e17eb52f4e64c097dc36f2f7.html “Symvivo Corporation is in Burnaby, BC, Canada and is part of the Biotechnology Research Services Industry. Symvivo Corporation has 3 total employees across all of its locations and generates $580,698 in sales (USD).”  Small venture capital and pre-trials - https://www.trialsitenews.com/ubc- dalhousie-university-commence-study-of-the-bactrl-spike-vaccine-targeting- covid-19/ “According to one profile, the venture has raised $2 million from a local early state venture investor and $100K from a National Research Council. Founder Graves started the company, along with Mark Fox—a friend from undergrad—as he realized “he sucked” at research but desired to leverage his scientific degree in meaningful ways. Graves and Fox sought to develop a platform that could accelerate drug development by focusing on the discovery—developing patents for aspects of the drug delivery process that could be licensed to drug makers”
  • 9.
    NOVOVAX  A smallgroup of scientists, execs, and VCs are $277 million richer as their companies race to create a coronavirus vaccine. Here are 7 who have raked in huge sums. - https://markets.businessinsider.com/news/stocks/coronavirus-drugmakers-moderna- gilead-novavax-stock-price-profit-millions-shareholders-2020-2-1028949761  Stock sales due to trials - https://www.bizjournals.com/washington/news/2020/05/20/novavax-prepares-stock- sale-as-covid-19-vaccine.html  https://finance.yahoo.com/news/novavax-nvax-stock-come-too-224659672.html “Vaccine specialist Novavax (NVAX) stepped up to the plate, and hit the ball out of the park yet again. Investors had already enjoyed some pretty hefty gains in 2020 before more positive developments sent the stock into the stratosphere. Last week, news that Novavax had received a $384 million grant from the Coalition for Epidemic Preparedness Innovations (CEPI) to support the development of its COVID-19 vaccine candidate, NVX-CoV2373, resulted in a 133% addition to the share price”  Coalition Preparedness https://cepi.net/about/whoweare/ - CEPI has secured financial investment from the Governments of Australia, Belgium, Canada, Denmark, Ethiopia, Finland, Germany, Japan, the Kingdom of Saudi Arabia, the Netherlands, Norway, the UK and Switzerland, as well as the Bill & Melinda Gates Foundation, and Wellcome. The European Commission provides substantial financial contributions to support relevant projects through its mechanisms. CEPI has also received donations from the private sector and individuals through the UN Foundation’s COVID-19 Solidarity Response Fund to support our COVID-19 vaccine development efforts.
  • 10.
    CUREVAC  As therace to develop a coronavirus vaccine intensifies, one player— German drugmaker CureVac—is backed by particularly deep pockets. CureVac, which is in the headlines amid rumors that the U.S. government offered funding to lure its research exclusively to America, counts one of Germany’s richest entrepreneurs, Mexican shopping mall tycoons and the Bill and Melinda Gates Foundation among its investors. https://www.forbes.com/sites/martaorosz/2020/03/16/these-are-the- billionaire-investors-behind-german-drugmakers-developing-a- coronavirus-vaccine/#78c83f841fb8  Regulators / Germany https://www.ft.com/content/7409dbae-6b4f- 4be0-ba75-46ed52e951ae  In the race to find a medical breakthrough to the pandemic, the startup, CureVac, said earlier this month that its proprietary technology has found suitable candidates that could lead to a treatment, and that it aims to start clinical trials in early summer. CureVac has received funding from the Bill & Melinda Gates Foundation. - https://fortune.com/2020/03/16/coronavirus-cure- trump-businesses-biotech/
  • 11.
    GENEREX  Manufacturing ofpeptide - https://www.globenewswire.com/news- release/2020/05/04/2026744/0/en/Generex-Biotechnology- Initiates-Peptide-Manufacturing-for-Ii-Key-SARS-CoV-2-Peptide- Vaccine-Against-the-COVID-19-Pandemic.html  Stock/Generex- https://www.fool.com/investing/2020/05/17/is- buying-a-basket-loaded-with-every-coronavirus-v.aspx “BIO, the biggest trade group representing the biotechnology industry, currently lists 28 companies that are actively involved in developing COVID-19 vaccines. Here are the 21 of those drugmakers that are publicly traded:”
  • 12.
    VAXART  SOUTH SANFRANCISCO, Calif., May 20, 2020 (GLOBE NEWSWIRE) -- Vaxart, Inc. (“Vaxart” or the “Company”) (NASDAQ: VXRT), a clinical- stage biotechnology company developing oral recombinant vaccines that are administered by tablet rather than by injection, today announced that it has selected its lead COVID-19 vaccine candidate and has contracted with KindredBio to manufacture bulk vaccine under cGMP to complement the manufacturing capacity of partner Emergent BioSolutions https://www.globenewswire.com/news- release/2020/05/20/2036357/0/en/Vaxart-Announces-Selection-of- its-Oral-COVID-19-Vaccine-Lead-Candidate.html  Funding issues - https://seekingalpha.com/article/4334623-vaxarts- coronavirus-stock-bump-is-unlikely-to-continue-exit-now-be-long  Cash on hand - https://www.fool.com/investing/2020/04/28/why- vaxart-stock-slumped-today.aspx  Partnerships - https://observer.com/2020/05/covid-19-vaccine- moderna-results-new-progress/
  • 13.
    MEDICAGO  Quebec Funding- https://www.canadianmanufacturing.com/research-and- development/government-of-quebec-providing-7m-to- medicagos-covid-19-vaccine-development-249412/  Animal Trials - https://www.sttinfo.fi/tiedote/medicago- announces-positive-results-in-animal-trials-for-its-vaccine- candidate-against-covid- 19?publisherId=58763726&releaseId=69881188  Collaborative project of more than $1.2 million using artificial intelligence to optimize the production of vaccines, announced by CQDM and Medicago R&D - https://www.newswire.ca/news- releases/collaborative-project-of-more-than-1-2-million-using- artificial-intelligence-to-optimize-the-production-of-vaccines- announced-by-cqdm-and-medicago-r-amp-d-859733879.html
  • 14.
    TAKIS  “TAKIS SRLis located in ROMA, ROMA, Italy and is part of the Scientific Research & Development Services Industry. TAKIS SRL has 15 employees at this location and generates $1.78 million in sales (USD). There are 4 companies in the TAKIS SRL corporate family. https://www.dnb.com/business-directory/company- profiles.takis_srl.1084976c4f88cf6ddd4089044968c511.html  Startup - https://www.forbes.com/sites/giacomotognini/2020/04/21/inside -the-tiny-italian-biotech-startup-racing-to-develop-a- coronavirus-vaccine/#b686e172c106  Funding - https://finance.yahoo.com/news/applied-dna-takis- biotech-announce-070000273.html
  • 15.
    UPDATE – VACCINES / DEVELOPMENT Source- “” https://www.healthline.com/healt h-news/heres-exactly-where- were-at-with-vaccines-and- treatments-for-covid-19
  • 16.
    VACCINES DEVELOPMENT  GSK- https://indianexpress.com/article/coronavirus/coronavirus-covid-19-vaccine-glaxosmithkline-oxford- astrazeneca-moderna-clover-status-check-6469474/  Vaccine Tracker - https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html  Gavi organization funding from sources like Bill Gates and world governments - https://www.biopharma- reporter.com/Article/2020/06/17/Gavi-receives-billions-in-funding  Gates and Inovio - https://www.newsbreak.com/missouri/kansas-city/news/0OfXdfSR/a-potential-coronavirus- vaccine-funded-by-bill-gates-is-set-to-begin-testing-in-people-with-the-first-patient-expected-to-get-it- today
  • 17.
    ALTIMUNE  “Shares ofAltimmune (ALT) - Get Report soared Thursday after the clinical-stage biopharmaceutical company announced the next step in development of its coronavirus vaccine AdCovid. “In collaboration with the University of Alabama at Birmingham, we have commenced preclinical testing of candidates for our Covid- 19 vaccine, AdCovid,” the company said in a statement. https://www.thestreet.com/investing/altimmune-coronavirus- vaccine-preclinical-trial  Former Pfizer board director appointed to Altimmune - https://www.reuters.com/companies/ALT.OQ
  • 18.
    TESTING  COVID19 –Testing “It uses a simple assay containing plasmonic gold nanoparticles to detect a color change when the virus is present. The test does not require the use of any advanced laboratory techniques, such as those commonly used to amplify DNA, for analysis. The authors published their work last week in the American Chemical Society’s nanotechnology journal ACS Nano. "Based on our preliminary results, we believe this promising new test may detect RNA material from the virus as early as the first day of infection. Additional studies are needed, however, to confirm whether this is indeed the case,” said study leader Dipanjan Pan, PhD, professor of diagnostic radiology and nuclear medicine and pediatrics at UMSOM.” https://www.umaryland.edu/news/archived-news/may-2020/covid-19- results-in-10-minutes-umb-studies-rapid-test.php or https://www.nextbigfuture.com/2020/05/ten-minute-covid-19- detection-test-using- nanoparticles.html?utm_source=feedburner&utm_medium=feed&utm_ campaign=Feed%3A+blogspot%2Fadvancednano+%28nextbigfuture% 29
  • 19.
    TESTING KITS Source -https://www.medtechdive.com/news/coronavirus-tests-home-collection-quest-diagnostics- letsgetchecked/578837/ The cost is $129 per kit!
  • 20.
    GLOBAL MARKET /TESTING Source - https://www.globenewswire.com/news-release/2020/06/01/2041269/0/en/Global-COVID-19-diagnostic-testing-market-to-amass-USD-44481-8-million-in-2020.html • Additional costs to already strapped healthcare system • Private insurance companies and their coverage in terms of their testing. This could mean a rise in premiums • Consumers could be out of pocket about $129 per test.
  • 21.
  • 22.
    ANTIBODIES  “Much remainsto be learnt about the immunological responses to SARS-CoV-2. Nevertheless, it is becoming clear that antibodies taken from the blood serum of people who have recovered from COVID-19 can be used for treatment by being transfused into other people who have the disease”Source - https://www.nature.com/articles/d41586-020-01816-5  Disappearance of antibodies 2-3 months - https://www.medscape.com/viewarticle/932671  “Those who did not have a bad case of COVID-19 lose antibodies faster. Forty percent of asymptomatic individuals became seronegative and 12.9% of the symptomatic group became negative for IgG in the early convalescent phase. In addition, asymptomatic individuals exhibited lower levels of 18 pro- and anti-inflammatory cytokines. These data suggest that asymptomatic individuals had a weaker immune response to SARS- CoV-2 infection.mThe research, published in Nature Medicine on June 18, highlights the risks of using COVID-19 ‘immunity passports’ and supports the prolonged use of public health interventions such as social distancing and isolating high-risk groups This seems to indicate that our better bet is t-cell-related therapies and vaccines and hygiene and social distancing.  Avoid getting together with larger groups  Stay 6-10 ten feet apart if at all possible  clean your hands every hour  Source - https://www.nextbigfuture.com/2020/06/coronavirus-antibody-immunity-fades-by-70-within-2-3- months.html?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+blogspot%2Fadvancednano+%28nextbigfuture%29
  • 23.
    GENE RESEARCH  Genomesequencing - https://globalnews.ca/news/7072424/alberta-researchers-genome-sequence-covid-19/  AI and Genome sequencing - http://www.genomequebec.com/486-en/news-covid-19-unprecedented- research-combining-genomics-and-artificial-intelligenceicial-intelligence/  Blood type and genome - https://directorsblog.nih.gov/2020/06/18/genes-blood-type-tied-to-covid-19-risk- of-severe-disease/
  • 24.
    MITIGATION  Shutting downan economy should be last resort  Private sector is driven by cash flow.  The focus should be on infrastructure, getting goods to market, supply chain, advance technology and reforming of government - https://www.slideshare.net/paulyoungcga/canada-gdp-and-economy-truth-and-what-needs-to-change  All levels of government should review their pandemic responses to ensure they have updated their playbook  Annual audits of risk and crisis management should be completed each year - https://www.slideshare.net/paulyoungcga/the-role-of-operational-and- performancebased-auditing-on-government-and-the-private-sector  WHO needs to provide reports on virus threats including what needs to be done to mitigate the spread  https://www.slideshare.net/paulyoungcga/crisis-management-how-best-to-managed-a-crisis  More coordination by the WHO with all government including monthly status calls around threats  Reporting should also be provided on the threats including performance audits of various WHO programs  Mitigating the spread is to ensure healthcare is provided with the necessary equipment - https://www.cdc.gov/coronavirus/2019-ncov/hcp/ppe-strategy/index.html  Sterilization methods of equipment and masks - https://www.inthehammer.com/hamilton-firms-technology-addresses-covid- waste-and-ppe-shortage  Protecting the most vulnerable  Screening at hospitals and long-term care facilities  Restricting the movement of staff between facilities
  • 25.
    UPDATE – JUNE23, 2020 TO JULY 1, 2O20  State of affairs with COVID19 - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines- and-treatments-for-covid-19  Line is forming for the vaccine - https://www.sciencemag.org/news/2020/06/line-forming-covid-19-vaccine-who- should-be-front  You cannot shut down the economy, but all levels of government including the private sector need to take mitigating steps - https://www.slideshare.net/paulyoungcga/transforming-the-economy-postcovid19-canada-and-the-world  China is using the pandemic to make changes with laws for Hong Kong - https://www.cnn.com/2020/07/01/asia/hong-kong-national-security-law-intl-hnk/index.html  USA buys up key drug - https://globalnews.ca/news/7127951/us-remdesivir-supply-coronavirus/  Antibody treatment - https://www.cnn.com/2020/06/26/health/antibody-therapies-covid-19-update- wellness/index.html
  • 26.
    VACCINES, HEALTH ANDSAFETY AND TESTING UPDATE  USA clinical trials - https://globalnews.ca/news/7178006/us-coronavirus-vaccine-testing/  Human trials in Quebec - https://www.cbc.ca/news/health/human-trials-covid-19-vaccine-candidate-quebec-1.5648648  World and treatment of COVID19 - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and-treatments-for-covid- 19#Antivirals  Vaccines Trials - https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html  Mobile testing kits - https://www.thestar.com/business/2020/07/09/guelph-companys-mobile-covid-19-test-kit-hits-market-and-heads-for- norther-ontario.html  Workplace measures - https://www.ontario.ca/page/develop-your-covid-19-workplace-safety-plan or http://www.worksafesask.ca/covid- 19/conducting-a-hazard-assessment-and-developing-a-safety-plan/  Mobile workers - https://www.carsondesign.com/2017/12/designing-your-office-space-for-the-mobile-workforce/  Vaccines trials - https://www.nytimes.com/interactive/2020/science/coronavirus-vaccine-tracker.html or https://newsinteractives.cbc.ca/coronavirusvaccinetracker/  Government of Canada order doses - https://www.ctvnews.ca/canada/feds-order-supplies-to-give-two-doses-of-covid-19-vaccine-when-it-s- ready-1.5029530  Status of treatments and Vaccines – August 16, 2020 - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and- treatments-for-covid-19#Vaccines  Treatments - https://catsroundtable.com/yale-prof-harvey-risch-hydroxychloroquine-hcq-covid-19/  Vaccines and drugs - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and-treatments-for-covid-19#Other- treatments 
  • 27.
    CONTACT TRACING  Developmentof contact tracing- “Contact tracing is the public health practice of informing people when they've been exposed to a contagious disease. As it has become more widely employed across the U.S., it has also become mired in modern political polarization and conspiracy theories.” - https://www.npr.org/sections/health- shots/2020/07/14/890628203/conspiracy-theories-aside-heres-what-contact-tracers-really-do  Privacy issues with contact tracing  One of the biggest challenges, experts told a congressional panel this week, is dispelling the unease people feel about the government or private companies gaining access to their personal data - https://www.marketwatch.com/story/us-contract-tracing-efforts-on-covid-19-falter-on-privacy- worries-technology-gap-2020-07-09  Data privacy laws like HIPAA, PIPDEA and EUGRP collide with contact tracing - https://www.reuters.com/article/bc-finreg-data-privacy-contact- tracing/data-privacy-laws-collide-with-contact-tracing-efforts-privacy-is-prevailing-idUSKCN24M1NL  There needs to be audits of the application on routine basis - https://priv.gc.ca/en/privacy-topics/health-genetic-and-other-body- information/health-emergencies/rev_covid-app/ . All levels of government can automate the audit process through AI and Analytics - https://www.slideshare.net/paulyoungcga/internal-audit-and-performance-base-auditing
  • 28.
    MEDICAL SUPPLIES ANDEQUIPMENT  Companies continue to ramped up production of ventilators - https://www.globenewswire.com/news- release/2020/07/22/2065727/0/en/191-Million-Worldwide-Ventilator-Test-Systems-Industry-to-2027-Impact-of- COVID-19-on-the-Market.html  Global Production - https://www.supplychainbrain.com/articles/31024-coronavirus-watch-governments-rush-to- secure-ventilators  Canada medical supplies and equipment  https://www.tpsgc-pwgsc.gc.ca/comm/aic-scr/provisions-supplies-eng.html  There needs to be an audit the readiness of medical supplies and equipment  Liberals  Masks production - https://torontosun.com/news/national/company-awarded-380m-in-contracts-but-fails-to-provide-masks- blacklocks-reporter  Ventilators - https://thepostmillennial.com/contract-awarded-to-former-liberal-mps-company-to-make-10-000-unapproved- ventilators
  • 29.
    JUSTIN TRUDEAU ANDPANDEMIC MANAGEMENT https://www.ctvnews.ca/health/coronavirus/the-fall-will-be-a-period-of-challenge-in-coronavirus-fight-canada-s-top-doctor-says- 1.5055678?taid=5f2e1fbcd7d51b0001834cab&utm_campaign=trueAnthem%3A+Trending+Content&utm_medium=trueAnthem&utm_sourc e=twitter When is @CPHO_Canada stepping down as Ms. Tam is not up to any challenge when it comes to protecting the healthcare system? 1. Healthcare - https://www.slideshare.net/paulyoungcga/race-for-covid19-vaccines-and-treatments or https://www.slideshare.net/paulyoungcga/reforming-healthcare 2. PPE Supply - https://news.ontario.ca/opo/en/2020/08/ontario-partners-with-federal-government-and-3m-canada-on-new-n95-respirator- manufacturing-facility.html 3. People are still entering Canada from hot spots despite saying the border was closed - https://www150.statcan.gc.ca/t1/tbl1/en/tv.action?pid=2410000301 4. Migrant program and disease management audit - https://www.thestar.com/business/2020/08/20/migrant-worker- program-to-undergo-federal-audit-following-massive-covid-19-outbreaks-on-canadian-farms.html 5. Health Canada and drug issues - https://www.ottawamatters.com/national-news/talks-needed-on-decriminalizing-hard-drugs-to-address- opioid-crisis-tam-says-2657216 6. Quebec and Contract tracing - https://www.halifaxtoday.ca/national-news/quebec-wont-ask-population-to-use-covid-19-contact-tracing- smartphone-app-2663902 - Quebec is concern with privacy issues 7. Funding to Education - https://globalnews.ca/news/7298419/feds-2-billion-school-coronavirus/ - Education is a provincial issue -
  • 30.
    DONALD TRUMP ANDPANDEMIC  Travel restrictions - https://www.bbc.com/news/world-us-canada-51846923  Pandemic funding - https://home.treasury.gov/policy-issues/cares CARES act was held up by Nancy Pelosi - https://www.foxnews.com/politics/mccarthy-blames-pelosi-wish-list-coronavirus-stimulus-bill  State and local funding - https://www.mckinsey.com/industries/public-and-social-sector/our-insights/us- coronavirus-relief-funds-a-guide-for-state-and-local-governments  Assisted living - https://www.whitehouse.gov/briefings-statements/president-donald-j-trump-is-taking- decisive-action-to-protect-vulnerable-citizens-in-americas-nursing-homes/  Blood treatment - https://globalnews.ca/news/7293522/donald-trump-fda-deep-state-coronavirus-vaccine/
  • 31.
    CDC / DEATHS Source- https://local12.com/news/nation-world/cdc-94-of-covid-19-deaths-had-underlying-medical-conditions-coronavirus-centers-for-disease-control or https://www.cdc.gov/nchs/nvss/vsrr/covid_weekly/index.htm?fbclid=IwAR3-wrg3tTKK5-9tOHPGAHWFVO3DfslkJ0KsDEPQpWmPbKtp6EsoVV2Qs1Q or https://nbc25news.com/news/local/cdc-94-of-covid-19-deaths-had-underlying-medical-conditions
  • 32.
    HEALTHCARE SURVEILLANCE Source -https://nationalpost.com/news/politics/canada-spent-147m-on-a-public-health-surveillance-system-that-isnt-being-used-during-covid-pandemic/wcm/e14f04a1-5314-4c55-a883- 57eeacd3b3e1/ • This was even a Liberal system brought in by Paul Martin
  • 33.
    TRAVEL / CANADA Source- https://www150.statcan.gc.ca/n1/daily-quotidien/200916/dq200916e-cansim-eng.htm
  • 34.
    FISCAL MANAGEMENT https://www.bnnbloomberg.ca/federal-deficit-hit-170-5b-through-august-on-emergency-spending-1.1515602 “Speaking tothe Montreal Chamber of Commerce this morning, Freeland says the spending may seem enormous, but doing any less would cost the country much more economically. No mentioned of stimulus in many cases was poorly targeted My work https://www.slideshare.net/paulyoungcga/fiscal-management-canada-october-2020
  • 35.
    NO LOCKDOWN Source - https://eur04.safelinks.protection.outlook.com/?url=https%3A%2F%2Fsiteproxy.ruqli.workers.dev%3A443%2Fhttps%2Fp.feedblitz.com%2Fr3.asp%3Fl%3D173343217%26f%3D64651%26c%3D0%26u%3D15561131&data=02%7C01%7C%7Cfc632a000624411046bd08d86e72a649%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637380785975473172&sdata=KNql94 1j%2BqzPgI8k2HkpS2avk7%2Ba4y6eb4xjBjZbUy8%3D&reserved=0 •All levels of government need to have risk and crisis management plans - https://www.slideshare.net/paulyoungcga/ how-to-implement-crisis-management- using-data-and-ai • The world needs to have performance audits of all organizations like WHO - https://www.slideshare.net/paulyoungcga/ internal-audit-and-governance-modeling- public-and-private-sector
  • 36.
    WHO / TEDROS @DrTedroshas history of coverups https://www.theglobeandmail.com/world/article-questions-surfacing-about- history-of-whos-director-tedros-adhanom/ or https://www.orfonline.org/expert-speak/dr-cover-up-tedros-adhanoms- controversial-journey-to-the-who-65493/ The WHO also needs to be reformed - https://www.slideshare.net/paulyoungcga/reforming-both-the-united- nations-and-who
  • 37.
    CORONAVIRUSES Source - https://www.cdc.gov/coronavirus/types.html •229E (1960s) - https://www.atsjournals.org/doi/full/10.1164/rccm.201506- 1239LE • NLG63 – (1960s) - https://www.atsjournals.org/doi/full/10.1164/rccm.201506- 1239LE • OC43 – common cold - https://academic.oup.com/cid/article/36/8/985/449256 • HKU1 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374449/ • SARS and other viruses never shutdown the economy • Global Economy could take years to recovered - https://www.slideshare.net/paulyoungcga/what-is- next-for-the-global-economy-october-2020 • There is job crisis in Canada as well as around the world - https://www.slideshare.net/paulyoungcga/pandem ic-and-covid19-canada-and-the-world • More needs to be done to protect healthcare and those most vulnerable - https://www.slideshare.net/paulyoungcga/how- do-you-fixed-assisted-living
  • 38.
    CLINICAL TRIALS –COVID19 VACCINES – OCTOBER 12 TO OCTOBER 19  Canada - https://www.canada.ca/en/health-canada/services/drugs-health-products/covid19-industry/drugs- vaccines-treatments/list-authorized-trials.html  USA - https://www.nih.gov/news-events/news-releases/nih-begins-large-clinical-trial-test-immune-modulators- treatment-covid-19  J&J pause - https://www.jnj.com/our-company/johnson-johnson-temporarily-pauses-all-dosing-in-our-janssen- covid-19-vaccine-candidate-clinical-trials  Vaccines - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and-treatments- for-covid-19  Vaccines (October 31 to November 7, 2020) –  Nature - https://www.nature.com/articles/d41586-020-00502-w  Vaccines - https://www.biopharmadive.com/news/coronavirus-vaccine-pipeline-types/579122/
  • 39.
    LATEST – PANDEMIC– COVID19  Vaccines timeline - https://www.healthline.com/health-news/heres-exactly-where-were-at-with-vaccines-and- treatments-for-covid-19#COVID-19-vaccines  Vaccines and world economy - https://www.wsj.com/articles/a-covid-19-vaccine-would-boost-the-global- economy-but-not-all-at-once-11605087345  World Meter - https://www.worldometers.info/coronavirus/  Elon Musk testing both positive and negative for COVID19 https://www.wsj.com/articles/tesla-ceo-elon-musk- says-he-tested-both-positive-and-negative-for-covid-19-11605251724  Testing Kits - https://www.ehstoday.com/health/article/21129419/fda-authorizes-athome-covid19-tests
  • 40.
    VACCINES  Pfizer -https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-conclude-phase- 3-study-covid-19-vaccine  Moderna - https://investors.modernatx.com/news-releases/news-release-details/modernas-covid-19-vaccine- candidate-meets-its-primary-efficacy
  • 41.
    STORAGE / VACCINES Youare asking for more than @CPHO_Canada and @PattyHajdu are willing to give in terms of information 1. Cold Storage - https://ca.finance.yahoo.com/news/cold-chain-throws-cold-water-over-pfizer-vaccine-hopes- 133716649.html 2. Supply/Market - https://www.grandviewresearch.com/industry-analysis/biomedical-refrigerators-and-freezers-market 3. Dry Ice - https://www.marketwatch.com/press-release/global-dry-ice-market-size-in-2020-industry-demand-market- share-trend-industry-news-business-growth-top-key-players-top-countries-analysis-and-outlookshowing-impressive- growth-by-2026-2020-09-03 My work on the pandemic - https://www2.slideshare.net/paulyoungcga/crisis-management-pandemic-covid19 Source - https://globalnews.ca/video/7470702/coronavirus-otoole-questions-trudeau-on-freezer- capacity-for-possible-covid-19-vaccine
  • 42.
    LATEST ON COVID19 Vaccine reset - https://www.statnews.com/2020/10/29/it-may-be-time-to-reset-expectations-on-when-well- get-a-covid-19-vaccine/  Latest on vaccines - https://www.nationalgeographic.com/science/health-and-human-body/human- diseases/coronavirus-vaccine-tracker-how-they-work-latest-developments-cvd/  PPE Supply - https://www.modernhealthcare.com/supply-chain/hospitals-say-theyre-better-prepared-ppe- spring-supply-chain-uncertain  Reforming Healthcare - https://www.hfma.org/topics/hfm/2020/november/reimagining-the-healthcare- supply-chain-to-bolster-resilience-an.html
  • 43.
    REFORMING HEALTHCARE -DIGITAL HOSPITAL https://www.canadianmanufacturing.com/technology/covid-19-sparks-boom-in-digital-hospitals-with-smart-technologies- improving-quality-of-care-262683/ “COVID-19 sparks boom in digital hospitals with smart technologies, improving quality of care” I have written many blogs on the transformation of healthcare https://www.slideshare.net/paulyoungcga/how-does-the- world-transform-healthcare-238832381
  • 44.
    COVID19 WILL HELPTRANSFORM HEALTHCARE  https://www.cfo.com/health-benefits/2020/10/7-ways-covid-19-will-transform-health- care/?utm_campaign=CFODailyAlert&utm_nooverride=1&utm_source=CFO- email&utm_medium=email&utm_content=CFODailyAlert_Wednesday_2020-10-14&utm_term=health-benefits Great Article with focus on the following areas: 1. Rise of Virtual Care 2. New digital approaches to meeting mental health needs 3. More entrepreneurial health care startups 4. Provider consolidation 5. More govt involvement 6. Increase in price sensitivity 7. Easing of regulation My analysis - https://www.slideshare.net/paulyoungcga/how-does-the-world-transform-healthcare-238832381
  • 45.
    GLOBAL ECONOMY  Manybusinesses are more prepared for future geopolitical events. The use of AI and Analytics as part of the close, consolidate, and reporting cycle is helping businesses better manage risk - https://www.slideshare.net/paulyoungcga/understanding-risks-as-part-of-development-risk- management-best-practices  Progressive need to stop pushing the global climate agenda as part of their various countries reset - https://www.slideshare.net/paulyoungcga/clean-technology-and-the-green-economy-what-is-next  There are many risks to the world economy - https://www.imf.org/en/Publications/WEO/Issues/2020/09/30/world-economic-outlook-october- 2020  Businesses are pushing back - https://www.talentcanada.ca/ontario-restaurants-ask-province-to-explain-restrictions-show-covid-19-data/ Other Sources  G7 - https://www.slideshare.net/paulyoungcga/what-is-next-for-g7-countries  Circular Economy - https://www.slideshare.net/paulyoungcga/how-to-best-support-a-circular-economy  Global - https://www.slideshare.net/paulyoungcga/what-is-next-for-the-global-economy-september-2020  Canada GDP / August 2020 - https://www.slideshare.net/paulyoungcga/gdp-canada-august-2020  Macros and Micro Indicators - https://www.slideshare.net/paulyoungcga/liberal-party-of-canada-fiscal-and-economic-scorecard-august-2020- and-september-2020
  • 46.
    CASES AND DEATH Source- https://www.nbc.ca/en/rates-and- analysis/economic-analysis.html
  • 47.
    WORLD WIDE DEATHS Source -- https://www.nbc.ca/en/rates-and- analysis/economic-analysis.html
  • 48.
    STORAGE Vaccines freezing market– 1. Cold Storage - https://ca.finance.yahoo.com/news/cold-chain-throws-cold-water-over-pfizer-vaccine-hopes- 133716649.html 2. Supply/Market - https://www.grandviewresearch.com/industry-analysis/biomedical-refrigerators-and-freezers- market 3. Dry Ice - https://www.marketwatch.com/press-release/global-dry-ice-market-size-in-2020-industry-demand- market-share-trend-industry-news-business-growth-top-key-players-top-countries-analysis-and-outlookshowing- impressive-growth-by-2026-2020-09-03 My work on the pandemic - https://www2.slideshare.net/paulyoungcga/crisis-management-pandemic-covid19
  • 49.
    TRAINING AND DEVELOPMENT If you like to learn more about trade and/or other subjects as part of your professional learning and development then feel free to review my material on https://www.udemy.com/ (search Paul Young CPA CGA)  These subjects address how to fixed issues with housing and/or systemic issues related to economy including government policies
  • 50.
    SUMMARY  There aremany companies involved with research and development of COVID19 vaccine - https://www.scienceboard.net/index.aspx?sec=sup&sub=imm&pag=dis&ItemID=677  Bill and Melinda Gates Foundation are playing a key role with funding and manufacturing - https://www.geekwire.com/2020/gates-foundation-commits-50m- covid-19-vaccine-initiative-total-funding-now-tops-300m/ (Funding is now over $300M (USD)  There are allot of startups involved. Various Canadian governments have been funding VC companies related to biotech research  There appears to be lack of progress reports on the state of affairs when it comes to government money going to vaccinations R&D - https://cmajnews.com/2020/05/20/coronavirus-1095847/  There is allot of speculator investments going on with biotech companies as part of reaping the rewards when vaccines go to market.  Major pharma continues to work with government, institution, labs, Tech, etc. https://www.bioworld.com/articles/435263-astrazeneca-moving-at-warp-speed-with- 12b-in-barda-funding-for-covid-19-vaccine  Medical Products - https://www.dailymail.co.uk/health/article-8717013/Scarcity-key- material-squeezes-medical-mask-manufacturing.html  Economy could see periods of slow growth for years - https://www.slideshare.net/paulyoungcga/transforming-the-economy-postcovid19- canada-and-the-world or https://www.investmentexecutive.com/news/research-and- markets/covid-19-to-reshape-economy-society-moodys/ or https://www.slideshare.net/paulyoungcga/gdp-canada-may-2020 or https://www.slideshare.net/paulyoungcga/global-economy-current-state-and-whats- next

Editor's Notes

  • #6 Source - https://www.raps.org/news-and-articles/news-articles/2020/3/covid-19-vaccine-tracker
  • #7 Moderna - https://investors.modernatx.com/financial-information/sec-filings and https://finance.yahoo.com/quote/MRNA/key-statistics/
  • #22 Source - https://www.theepochtimes.com/hydroxychloroquine-study-corrected-after-more-than-100-scientists-question-findings_3371001.html or https://www.marketwatch.com/press-release/hydroxychloroquine-market-2020-global-trends-growth-size-opportunities-regional-overview-leading-company-analysis-and-key-country-forecast-to-2026-2020-06-01?tesla=y or https://www.newindianexpress.com/states/karnataka/2020/apr/08/pharma-firms-await-ingredient-from-china-to-make-sought-after-drug-hcq-2127181.html