Excess body
fat
accumulated
to the extend
of causing
adverse
effect
Obesity in Asia
Journal of Obesity in Malaysia by
University Kebangsaan Malaysia states
that:
5.8% of 29,179,952-obese
Number of people obese are
1,692,437
Higher rate-Malays and Indians
 Environmental
factors
 Genetic factors
 Lack of sleep
 Age
 Gender
Childhood
Obesity
Adult Obesity
• Parental obesity
• Prader-Willi
syndrome
Genetic Factors
• Lack of physical
activity
• Sedentary lifestyle
• Over eating
Environmental
Factors
Adult
Obesity
Excess
body fat
Adipose tissue
is the form of
tissue that fat
takes in the
body.
Located just
beneath the skin
or between other
organs such as
the muscles and
heart.
Excess
carbohydrates,
proteins and
dietary fats can
be converted
into fatty acids
and stored as
adipose tissue in
the body.
Too much
adipose tissue
on your body,
it contributes
to serious
health
complications.
Expansion of the adipose tissue during weight gain leads tissue
undergoes a continuous remodeling process that normally
maintains tissue health, but may spin out of control and lead to
adipocyte death in association with the recruitment and
activation of macrophages, and systemic insulin resistance.
 Adipose tissue located beneath the skin
(subcutaneous fat), around internal organs (visceral
fat), in bone marrow (yellow bone marrow) and in
breast tissue.
 Adipose depots in different parts of the body have
different biochemical profiles.
 Under normal conditions, it provides feedback for
hunger and diet to the brain.
 Diseased fat tissue surrounding various organs can
cause illness.
 Aromatase which is involved in sex hormone metabolism.
 TNF Alpha, IL-6 and leptin which are collectively termed
„cytokines‟ and are involved in sending messages between cells.
 Plasminogen activator inhibitor-1 which is involved in the clotting
of blood.
 Angiotensin which is involved in blood pressure control.
 Adiponectin which improves the body‟s sensitivity to insulin and
so helps to protect against developing type 2 diabetes.
 Lipoprotein lipase and apolipoprotein E which are involved in
storage and metabolism of fat to release energy.
Type 2
diabetes
Excess
body fat
Difficulty
sleeping
extremely
large
waistline
Heavy
sweating
Lack of
energy
Pain and
soreness in
joints and
muscles
Symptoms
Consequences
of obesity
Coronary heart
disease
stroke
Type 2 diabetes
Non alcoholic
fatty liver
disease
(NAFLD)
cancer
High blood
pressure
Body mass index
BMI : BW / H2
Where :-
BW = Body Weight (kilograms)
H = Height (meters)
 Measure waist circumference
Apple shape ( risk of DM, CVD,
HTN )
Waist larger than 40 inch men
Waist larger than 35 inch women
 Overweight: BMI 25 - 29.9
 Obese: BMI > 30
 Obesity Class I: 30 - 34.9
 Obesity Class II: 35 - 39.9
 Extreme Obesity: >40
 Diet therapy
 Increased Physical Activity
 Pharmacotherapy
 Behavioral Therapy
 Surgery
 Highly ineffective rate 95 % long term failure
 Often result in increase weight than before diet
 Slow weight loss – stable
 Rapid weight loss – gain weight
 Rapid weight loss – increase risk of gallstones
 Low calorie step 1 diet
Women Men
1000 – 1200 kcal/day 1200-1600 kcal/day
Male Age 20-49 2900 calories/day
50 + 2500 calories/day
Female Age 20-49 2300 calories/day
50 + 1900 calories/day
Guideline Daily Amount Values
Typical values Women Men
Children (5-10
years)
Calories 2,000 kcal 2,500 kcal 1,800 kcal
Protein 45 g 55 g 24 g
Carbohydrate 230 g 300g 220 g
Sugars 90 g 120 g 85 g
Fat 70 g 95 g 70 g
Saturates 20 g 30 g 20 g
Fibre 24 g 24 g 15 g
Salt 6 g 6 g 4 g
 Integral part of weight loss
 Increase activity never loss weight
 Sustained activity does prevent weight regain
 Reduces risk of getting HD & DM
 Recommended activities
A) Sibutramine(Serotonin Nor-epinephrine Reuptake Inhibitor) :
initial dose 10mg/day, max 20mg/day. Reduces food intake,
increase HR and BP.
B) Orlistat:
Lipase inhibitor : 120mg PO TID. Alters metabolism, dec
absorption of dietary fat.
 Keep a journal of diet/diary
 Set spesific goals
 Keep track of improvement
Surgery Restrictive
Combined
restrictive &
malabsorption
Vertical band gastroplasty
Gastric Banding
Laproscopic gastric
banding
Roux-en-y gastric bypass
Biliopancreatic diversion
VBG
GASTRIC
BANDING
(LGB)
 P. Thamilselvi suffered obesity for years
 She had several complications due to
obesity for instance;
 She had difficulties of breathing while
doing heaving activities
 Stress and depression
 Thamilselvi consulted her physical dietician
She started a strict diet :
 Oats
 Green tea
 Green apple
 Cut down rice intake, oily foods and food
contain high fat
The latest Thamilselvi
 “Sebab mulut badan binasa” – “Body perish
because of the mouth”
 obesity is best tackled at home through improved
self involvement, increased physical exercise,
better diet and restraint from eating.
 Ismail MN. The nutrition and health transition in Malaysia.
Public Health Nutrition 2002; 5: 191–195.
 World Health Organization. Obesity: Preventing and Managing
the Global Epidemic. WHO Obesity Technical Report Series
no. 894. WHO: Geneva, 2000.
 Ismail MN, Tan CL. Prevalence of obesity in Malaysia. In:
Inoue & Zimmet (eds). The Asia–Pacific Perspective: Redefining
Obesity and its Treatment. WHO(WPRO)/IASO/IOTF: Health
Communications Australia, 2000 pp 10–13.
 Ismail MN, Vickneswary EN. Prevalence of obesity in
Malaysia: data from three ethnic populations. In: Inoue & Zimmet
(eds). The Asia – Pacific Perspective: Redefining Obesity and its
Treatment. WHO (WRRO)/IASO/10TF: Health Communication
Australia, 2000.
Obesity

Obesity

  • 2.
    Excess body fat accumulated to theextend of causing adverse effect
  • 4.
  • 5.
    Journal of Obesityin Malaysia by University Kebangsaan Malaysia states that: 5.8% of 29,179,952-obese Number of people obese are 1,692,437 Higher rate-Malays and Indians
  • 6.
     Environmental factors  Geneticfactors  Lack of sleep  Age  Gender
  • 7.
  • 8.
    • Parental obesity •Prader-Willi syndrome Genetic Factors • Lack of physical activity • Sedentary lifestyle • Over eating Environmental Factors
  • 9.
    Adult Obesity Excess body fat Adipose tissue isthe form of tissue that fat takes in the body. Located just beneath the skin or between other organs such as the muscles and heart. Excess carbohydrates, proteins and dietary fats can be converted into fatty acids and stored as adipose tissue in the body. Too much adipose tissue on your body, it contributes to serious health complications.
  • 10.
    Expansion of theadipose tissue during weight gain leads tissue undergoes a continuous remodeling process that normally maintains tissue health, but may spin out of control and lead to adipocyte death in association with the recruitment and activation of macrophages, and systemic insulin resistance.
  • 11.
     Adipose tissuelocated beneath the skin (subcutaneous fat), around internal organs (visceral fat), in bone marrow (yellow bone marrow) and in breast tissue.  Adipose depots in different parts of the body have different biochemical profiles.  Under normal conditions, it provides feedback for hunger and diet to the brain.  Diseased fat tissue surrounding various organs can cause illness.
  • 13.
     Aromatase whichis involved in sex hormone metabolism.  TNF Alpha, IL-6 and leptin which are collectively termed „cytokines‟ and are involved in sending messages between cells.  Plasminogen activator inhibitor-1 which is involved in the clotting of blood.  Angiotensin which is involved in blood pressure control.  Adiponectin which improves the body‟s sensitivity to insulin and so helps to protect against developing type 2 diabetes.  Lipoprotein lipase and apolipoprotein E which are involved in storage and metabolism of fat to release energy.
  • 14.
  • 15.
    Consequences of obesity Coronary heart disease stroke Type2 diabetes Non alcoholic fatty liver disease (NAFLD) cancer High blood pressure
  • 16.
    Body mass index BMI: BW / H2 Where :- BW = Body Weight (kilograms) H = Height (meters)  Measure waist circumference Apple shape ( risk of DM, CVD, HTN ) Waist larger than 40 inch men Waist larger than 35 inch women
  • 17.
     Overweight: BMI25 - 29.9  Obese: BMI > 30  Obesity Class I: 30 - 34.9  Obesity Class II: 35 - 39.9  Extreme Obesity: >40
  • 18.
     Diet therapy Increased Physical Activity  Pharmacotherapy  Behavioral Therapy  Surgery
  • 19.
     Highly ineffectiverate 95 % long term failure  Often result in increase weight than before diet  Slow weight loss – stable  Rapid weight loss – gain weight  Rapid weight loss – increase risk of gallstones  Low calorie step 1 diet Women Men 1000 – 1200 kcal/day 1200-1600 kcal/day
  • 20.
    Male Age 20-492900 calories/day 50 + 2500 calories/day Female Age 20-49 2300 calories/day 50 + 1900 calories/day Guideline Daily Amount Values Typical values Women Men Children (5-10 years) Calories 2,000 kcal 2,500 kcal 1,800 kcal Protein 45 g 55 g 24 g Carbohydrate 230 g 300g 220 g Sugars 90 g 120 g 85 g Fat 70 g 95 g 70 g Saturates 20 g 30 g 20 g Fibre 24 g 24 g 15 g Salt 6 g 6 g 4 g
  • 21.
     Integral partof weight loss  Increase activity never loss weight  Sustained activity does prevent weight regain  Reduces risk of getting HD & DM  Recommended activities
  • 22.
    A) Sibutramine(Serotonin Nor-epinephrineReuptake Inhibitor) : initial dose 10mg/day, max 20mg/day. Reduces food intake, increase HR and BP. B) Orlistat: Lipase inhibitor : 120mg PO TID. Alters metabolism, dec absorption of dietary fat.
  • 23.
     Keep ajournal of diet/diary  Set spesific goals  Keep track of improvement
  • 24.
    Surgery Restrictive Combined restrictive & malabsorption Verticalband gastroplasty Gastric Banding Laproscopic gastric banding Roux-en-y gastric bypass Biliopancreatic diversion
  • 25.
  • 27.
     P. Thamilselvisuffered obesity for years  She had several complications due to obesity for instance;  She had difficulties of breathing while doing heaving activities  Stress and depression
  • 28.
     Thamilselvi consultedher physical dietician She started a strict diet :  Oats  Green tea  Green apple  Cut down rice intake, oily foods and food contain high fat
  • 29.
  • 30.
     “Sebab mulutbadan binasa” – “Body perish because of the mouth”  obesity is best tackled at home through improved self involvement, increased physical exercise, better diet and restraint from eating.
  • 31.
     Ismail MN.The nutrition and health transition in Malaysia. Public Health Nutrition 2002; 5: 191–195.  World Health Organization. Obesity: Preventing and Managing the Global Epidemic. WHO Obesity Technical Report Series no. 894. WHO: Geneva, 2000.  Ismail MN, Tan CL. Prevalence of obesity in Malaysia. In: Inoue & Zimmet (eds). The Asia–Pacific Perspective: Redefining Obesity and its Treatment. WHO(WPRO)/IASO/IOTF: Health Communications Australia, 2000 pp 10–13.  Ismail MN, Vickneswary EN. Prevalence of obesity in Malaysia: data from three ethnic populations. In: Inoue & Zimmet (eds). The Asia – Pacific Perspective: Redefining Obesity and its Treatment. WHO (WRRO)/IASO/10TF: Health Communication Australia, 2000.