Dr Kiran Kumar K R
Professor
Dept of Oral Medicine
&
Radiology
• Navodaya Dental College
1
Odontogeni
c Cysts 2
Definition of the CYST
A Pathologic cavity having fluid ,semi fluid, or gaseous
contents and which is not created by accumulation of
pus.(KRAMER 1974.)
3
Classification of Cysts
I. Cysts of the Jaws
II. Cysts associated with the Maxillary antrum
III. Cysts of the soft tissues of the mouth , face, neck and salivary
glands
4
Classification of Cysts of the Jaws
I. Cysts of the Jaws
I(A). Epithelial lined II(B). Not epithelial
lined
5
I(A). Epithelial –lined cysts
(a). Developmental
origin
(b). Inflammatory
origin
(i).Odontogenic
(ii).Non-
Odontogenic
6
I(A)(a) DEVELOPMENTAL ORIGIN:-
• I(A)(a)(i) ODONTOGENIC-
i. Gingival cyst of infants
ii. Odontogenic keratocyst
iii. Dentigerous cyst
iv. Eruption cyst
v. Gingival cyst of adults
vi. Developmental lateral periodontal cyst
vii. Botryoid odontogenic cyst
viii. Gandular odontogenic cyst
ix. Calcifying odontogenic cyst
7
I(A)(a)(ii) NON –ODONTOGENIC :-
• Mid palatal raphe cyst of infants
• Nasopalatine duct cyst
• Nasolabial cyst
• II ( B)NON-EPITHELIAL –LINED CYSTS
• Solitary bone cyst
• Aneurysmal bone cyst
8
CYSTS ASSOCIATED WITH THE MAXILLARY ANTRUM:-
i. Mucocele
ii. Retention cyst
iii. Pseudo cyst
iv. Postoperative maxillary cyst
9
• CYSTS OF THE SOFT TISSUES OF THE MOUTH ,FACE
AND NECK:-
1. Dermoid and epidermoid cysts 9. Cyst of the
2. Lymphoepithelial (Branchial cyst) salivary glands
3. Thyroglossal duct cyst 10. Parasitic cysts
4. Anterior median lingual cyst
5. Oral alimentary tract cyst
6. Cystic hygroma
7. Nasopharyngeal cyst
8. Thymic cyst
10
WHO CLASSIFICATION OF CYSTS [1992]:-
• Dentigerous cyst
• Eruption cyst
• Odontogenic keratocyst
• Gingival Cyst of newborn
• Gingival Cyst of adult
• Lateral periodontal cyst
• Calcifying odontogenic cyst
• Glandular odontogenic cyst
Developmental cysts
• Radicular cyst
• Residual cyst
• Paradental cyst
Inflammatory cysts
11
12
13
RADICULAR CYST
Radicular cysts are the most common
inflammatory cysts and arise from the epithelial residues in the
periodontal ligament.
14
15
• RADIOGRAPHIC FEATURES:-
1. LOCATION:-
o Epicenter - Apex of non-vital tooth.
o Location - 60% maxilla - incisors & canines.
o Non-vital deciduous tooth.( Buccal to developing
bicuspid)
16
17
• PERIPHERY AND SHAPE:-
• Shape :Round to oval shape.
• Periphery: Well defined corticated border.
• If cyst is secondarily infected –border will be lost.
INTERNAL STRUCTURE:-
• Mostly radiolucent.
• Occasionally dystrophic calcification (in long standing cysts).
18
o EFFECTS ON SORROUNDING STRUCTURES:-
o Adjacent teeth - Displacement & resorption of the roots
o Nonvital tooth -resorption of the root rare.
o Expansion of outer cortical plates - maxilla / mandible
o Mandibular canal -displaced inferiorly
19
• DIFFERENTIAL DIAGNOSIS:-
• Periapical granuloma
• Odontogenic keratocyst
• Lateral periodontal cyst
• Peripical cemental dysplasia
20
RADICULAR CYST PERIAPICAL GRANULOMA
Size is ≥ 1cm. Size is ≤ 1cm.
Shape- Round
Border -Corticated
Oval
Sclerotic
21
RADICULAR CYST ODONTOGENIC
KERATOCYST
Tooth - Non vital Vital
Maxillary anterior teeth .
Cortical Expansion
Mandibular ramus area
No B-L Cortical Expansion
22
Dentigerous Cyst
• Definition :- A dentigerous cyst is one that encloses the crown
of an unerupted tooth by expansion of its follicle and is attached
to the neck.
• Browne & Smith - DENTIGEROUS CYST.
• Dentigerous = tooth bearing.
• Pathogenesis;
Disintegration of Stellate Reticulum epithelial cells
Accumulation of fluid in follicular space
23
• Clinical Features:-
• Second most common cyst.
• Peak - 2nd & 3rd decade.
• M:F::2:1.
• Site: Mandibular 3rd molar
Maxillary canine & Mandibular Premolars.
• May be associated with supernumerary tooth.
24
• Radiological features:-
• LOCATION:-
• Epicenter- Just above crown of the involved tooth.
• Imp- Cyst is attached at the CEJ
• 3 variants-
i. Central variety- Covering crown
25
i. Circumferential variety-
Covers the entire crown without occlusal surface
26
iii. Lateral variety-
Along lateral surface of root with partially
covering the crown.
27
• Inflammatory DC
–
– Spread of periapical infection non-vital deciduous tooth.
• Multiple DC
- Maroteaux- Lamy Syndrome
28
29
PERIPHERI & SHAPE:-
• Well defined - Circular or curved outline.
• Secondary infected – loss of corticated border.
INTERNAL STRUCTURE :-
• Completely radiolucent.
• Crown of involved tooth.
30
• Effects on surrounding structures:-
• Displaces & resorbs - adjacent teeth
• Tooth Displacement –apically.
• Slow growing cyst-expands cortices.
• If cyst involving
• maxillary 3rd molar- Floor of maxillary antrum displaced
superiorly
• mandibular 3rd molar- inferior alvoelar nerve canal- inferiorly
31
DENTIGEROUS CYST HYPERPLASTIC FOLLICLE
Follicular space > 5mm Normal Follicular space- 2-3mm
32
DENTIGEROUS CYST OKC
Expansion of cortical plates Less expansion
Adjacent tooth root resorption Less likely resorption
Lesion is attached to CEJ of
affected tooth
Lesion is more apically
33
DENTIGEROUS CYST AMELOBLASTIC FIBROMA
Associated with unerupted tooth Not associated with unerupted
tooth
Molar region Premolar –molar region
34
Rx
• Small-Enucleation
• Large- Marsupialization
Complications
– SCC
– Mucoepidermoid carcinoma
– Ameloblastoma 35
ODONTOGENIC KERATOCYST
• Synonym:- Primordial Cyst
• The term Odontogenic Keratocyst - Philipsen in 1956.
Pathogenesis:
36
Clinical features:-
• Bimodal age .
• 2 & 5th decade .
• Male predominence.
• Asymptomatic ,until secondarily infected .
• Less/no cortical expansion.
• On Aspiration – a thick, yellow, cheesey material of keratin.
37
• RADIOGRAPHIC FEATURES:-
LOCATION:- Posterior body of the mandible -90%
Ramus > 50%
EPICENTER:- Superior to inferior alveolar canal.
SHAPE :Smooth round or oval shape.
PERIPHERY :-
Corticated border unless secondarily infected.
Scalloped outline ( contiguous arcs).
38
39
INTERNAL STRUCTURES:-
• Multilocular radiolucency.- Radiolucent with curved internal
septa
Effects on surrounding structures:-
• Grow along medullary cavity of jaws.
• No/ Slight B-L expansion.
• Less resorption & displacement of the tooth.
40
Differential Diagnosis:-
• Dentigerous cyst
• Ameloblastoma
• Odontogenic myxoma
• Simple bone cyst.
41
Odontogenic Keratocyst Dentigerous cyst
Multilocular radiolucency Unilocular radiolucency
Less cortical expansion More buccal cortical expansion
Not often root resorption present Resorption & displacement
42
Odontogenic keratocyst Ameloblastoma
Less cortical expansion More cortical expansion
1st ,2nd or 3rd decades Older age
Paresthesia absent Paresthesia may be present
43
Odontogenic Keratocyst Odontogenic Myxoma
Radiolucent –multilocular ,soap
bubble appearance
Radiolucent-radiopaque, tennis
racket or step ladder appearance
Thin septa curved ,or cicular Thin etched septa is straight
always
44
Odontogenic Keratocyst Simple Bone Cyst
Scalloped borders mostly
towards the inferior border of
mandible
Scalloping borders towards the
crestal bone
Resorption or displacement of
tooth
No resorption or displacement
of tooth
Loss of lamina dura No loss of lamina dura
45
BASAL CELL NEVUS SYNDROME or
GORLIN-GOLTZ SYNDROME
Syndrome comprises of variety of abnormalities:-
1. B= Multiple nevoid Basal Cell Carcinomas of the skin.
2. S= Skeletal abnormalities.
3. C= Central nervous system abnormalities
4. M= Multiple odontogenic keratocyst.
5. EN= Endocrine system abnormality.
46
• Clinical features:-
• After 5 years of age & before 30 years.
• Skin lesions- small ,flattened, flesh or brown color papules on
face, trunk & neck.
47
• Basal cell carcinoma of the skin
48
• Skeletal abnormalities –Bifid rib, Synostosis of ribs.
49
• Multiple OKC in multiple sites of jaws.
50
• Costal abnormalities as agenesis , deformity, kyphoscoliosis,
vertebral fusion, polydactyly, shortening of metacarpals.
51
• Temporal & temperoparietal bossing.
52
• Minor hypertelorism.
• Mild prognathism.
• Calcification of falx cerebri & duramater in early life.
53
54
• DIFFERENTIAL DIAGNOSIS:-
• Multiple myeloma
• Cherubism
Basal Cell Nevus
Syndrome
Multiple Myeloma
Multilocular radiolucencies Multiple punched out
radiolucencies with
corticated borders.
55
56
Basal Cell Nevus Syndrome Cherubism
Multiple multilocular
radiolucency
No jaw expansion,
Bilateral multilocular
radioluceny.
Significant jaw expansion
No displacement of the teeth Pushes posterior teeth in
anterior direction
57
CALCIFYING EPITHELIAL ODONTOGENIC CYST
o Synonym- Calcifying Odontogenic cyst
o Gorlin cyst.
o Clinical features:-
o 1st peak is 10-19 years, 2nd peak is 7th decade.
o Slow-growing, painless swelling of jaw.
o Expansion destroy cortical plate.
o Advanced lesion--- discharge
58
• On ASPIRATION:- viscous, granular, yellow fluid.
• RADIOGRAPHIC INTERPRETATION:-
• Location– 75% anterior to the 1st molar.
Cuspid and premolar region.
Sometimes manifests as pericoronal radiolucencies.
• Peripheri & Shape– well defined corticated,
Ill defined & irregular in cyst like lesions .
59
• Internal structure:- varies usually…
completely radiolucent --- small evidence of
foci of calcified material .
• Effects on supporting structures:-
20%-50% commonly associated with cuspid & impedes its
eruption.
Displacement & resorption of roots
Perforation of cortical plate.
60
61
• Differential Diagnosis
• Dentigerous cyst
• Adenomatoid odontogenic tumour
• Ameloblastic fibro-odontoma
62
CEOC DENTIGEROUS CYST
Not evident always pericoronally Always pericoronal radiolucent
Tiny fleks of calcification masses
are evedent
Uniform radiolucent
63

ODONTOGENIC CYSTS.pptx

  • 1.
    Dr Kiran KumarK R Professor Dept of Oral Medicine & Radiology • Navodaya Dental College 1
  • 2.
  • 3.
    Definition of theCYST A Pathologic cavity having fluid ,semi fluid, or gaseous contents and which is not created by accumulation of pus.(KRAMER 1974.) 3
  • 4.
    Classification of Cysts I.Cysts of the Jaws II. Cysts associated with the Maxillary antrum III. Cysts of the soft tissues of the mouth , face, neck and salivary glands 4
  • 5.
    Classification of Cystsof the Jaws I. Cysts of the Jaws I(A). Epithelial lined II(B). Not epithelial lined 5
  • 6.
    I(A). Epithelial –linedcysts (a). Developmental origin (b). Inflammatory origin (i).Odontogenic (ii).Non- Odontogenic 6
  • 7.
    I(A)(a) DEVELOPMENTAL ORIGIN:- •I(A)(a)(i) ODONTOGENIC- i. Gingival cyst of infants ii. Odontogenic keratocyst iii. Dentigerous cyst iv. Eruption cyst v. Gingival cyst of adults vi. Developmental lateral periodontal cyst vii. Botryoid odontogenic cyst viii. Gandular odontogenic cyst ix. Calcifying odontogenic cyst 7
  • 8.
    I(A)(a)(ii) NON –ODONTOGENIC:- • Mid palatal raphe cyst of infants • Nasopalatine duct cyst • Nasolabial cyst • II ( B)NON-EPITHELIAL –LINED CYSTS • Solitary bone cyst • Aneurysmal bone cyst 8
  • 9.
    CYSTS ASSOCIATED WITHTHE MAXILLARY ANTRUM:- i. Mucocele ii. Retention cyst iii. Pseudo cyst iv. Postoperative maxillary cyst 9
  • 10.
    • CYSTS OFTHE SOFT TISSUES OF THE MOUTH ,FACE AND NECK:- 1. Dermoid and epidermoid cysts 9. Cyst of the 2. Lymphoepithelial (Branchial cyst) salivary glands 3. Thyroglossal duct cyst 10. Parasitic cysts 4. Anterior median lingual cyst 5. Oral alimentary tract cyst 6. Cystic hygroma 7. Nasopharyngeal cyst 8. Thymic cyst 10
  • 11.
    WHO CLASSIFICATION OFCYSTS [1992]:- • Dentigerous cyst • Eruption cyst • Odontogenic keratocyst • Gingival Cyst of newborn • Gingival Cyst of adult • Lateral periodontal cyst • Calcifying odontogenic cyst • Glandular odontogenic cyst Developmental cysts • Radicular cyst • Residual cyst • Paradental cyst Inflammatory cysts 11
  • 12.
  • 13.
  • 14.
    RADICULAR CYST Radicular cystsare the most common inflammatory cysts and arise from the epithelial residues in the periodontal ligament. 14
  • 15.
  • 16.
    • RADIOGRAPHIC FEATURES:- 1.LOCATION:- o Epicenter - Apex of non-vital tooth. o Location - 60% maxilla - incisors & canines. o Non-vital deciduous tooth.( Buccal to developing bicuspid) 16
  • 17.
  • 18.
    • PERIPHERY ANDSHAPE:- • Shape :Round to oval shape. • Periphery: Well defined corticated border. • If cyst is secondarily infected –border will be lost. INTERNAL STRUCTURE:- • Mostly radiolucent. • Occasionally dystrophic calcification (in long standing cysts). 18
  • 19.
    o EFFECTS ONSORROUNDING STRUCTURES:- o Adjacent teeth - Displacement & resorption of the roots o Nonvital tooth -resorption of the root rare. o Expansion of outer cortical plates - maxilla / mandible o Mandibular canal -displaced inferiorly 19
  • 20.
    • DIFFERENTIAL DIAGNOSIS:- •Periapical granuloma • Odontogenic keratocyst • Lateral periodontal cyst • Peripical cemental dysplasia 20
  • 21.
    RADICULAR CYST PERIAPICALGRANULOMA Size is ≥ 1cm. Size is ≤ 1cm. Shape- Round Border -Corticated Oval Sclerotic 21
  • 22.
    RADICULAR CYST ODONTOGENIC KERATOCYST Tooth- Non vital Vital Maxillary anterior teeth . Cortical Expansion Mandibular ramus area No B-L Cortical Expansion 22
  • 23.
    Dentigerous Cyst • Definition:- A dentigerous cyst is one that encloses the crown of an unerupted tooth by expansion of its follicle and is attached to the neck. • Browne & Smith - DENTIGEROUS CYST. • Dentigerous = tooth bearing. • Pathogenesis; Disintegration of Stellate Reticulum epithelial cells Accumulation of fluid in follicular space 23
  • 24.
    • Clinical Features:- •Second most common cyst. • Peak - 2nd & 3rd decade. • M:F::2:1. • Site: Mandibular 3rd molar Maxillary canine & Mandibular Premolars. • May be associated with supernumerary tooth. 24
  • 25.
    • Radiological features:- •LOCATION:- • Epicenter- Just above crown of the involved tooth. • Imp- Cyst is attached at the CEJ • 3 variants- i. Central variety- Covering crown 25
  • 26.
    i. Circumferential variety- Coversthe entire crown without occlusal surface 26
  • 27.
    iii. Lateral variety- Alonglateral surface of root with partially covering the crown. 27
  • 28.
    • Inflammatory DC – –Spread of periapical infection non-vital deciduous tooth. • Multiple DC - Maroteaux- Lamy Syndrome 28
  • 29.
  • 30.
    PERIPHERI & SHAPE:- •Well defined - Circular or curved outline. • Secondary infected – loss of corticated border. INTERNAL STRUCTURE :- • Completely radiolucent. • Crown of involved tooth. 30
  • 31.
    • Effects onsurrounding structures:- • Displaces & resorbs - adjacent teeth • Tooth Displacement –apically. • Slow growing cyst-expands cortices. • If cyst involving • maxillary 3rd molar- Floor of maxillary antrum displaced superiorly • mandibular 3rd molar- inferior alvoelar nerve canal- inferiorly 31
  • 32.
    DENTIGEROUS CYST HYPERPLASTICFOLLICLE Follicular space > 5mm Normal Follicular space- 2-3mm 32
  • 33.
    DENTIGEROUS CYST OKC Expansionof cortical plates Less expansion Adjacent tooth root resorption Less likely resorption Lesion is attached to CEJ of affected tooth Lesion is more apically 33
  • 34.
    DENTIGEROUS CYST AMELOBLASTICFIBROMA Associated with unerupted tooth Not associated with unerupted tooth Molar region Premolar –molar region 34
  • 35.
    Rx • Small-Enucleation • Large-Marsupialization Complications – SCC – Mucoepidermoid carcinoma – Ameloblastoma 35
  • 36.
    ODONTOGENIC KERATOCYST • Synonym:-Primordial Cyst • The term Odontogenic Keratocyst - Philipsen in 1956. Pathogenesis: 36
  • 37.
    Clinical features:- • Bimodalage . • 2 & 5th decade . • Male predominence. • Asymptomatic ,until secondarily infected . • Less/no cortical expansion. • On Aspiration – a thick, yellow, cheesey material of keratin. 37
  • 38.
    • RADIOGRAPHIC FEATURES:- LOCATION:-Posterior body of the mandible -90% Ramus > 50% EPICENTER:- Superior to inferior alveolar canal. SHAPE :Smooth round or oval shape. PERIPHERY :- Corticated border unless secondarily infected. Scalloped outline ( contiguous arcs). 38
  • 39.
  • 40.
    INTERNAL STRUCTURES:- • Multilocularradiolucency.- Radiolucent with curved internal septa Effects on surrounding structures:- • Grow along medullary cavity of jaws. • No/ Slight B-L expansion. • Less resorption & displacement of the tooth. 40
  • 41.
    Differential Diagnosis:- • Dentigerouscyst • Ameloblastoma • Odontogenic myxoma • Simple bone cyst. 41
  • 42.
    Odontogenic Keratocyst Dentigerouscyst Multilocular radiolucency Unilocular radiolucency Less cortical expansion More buccal cortical expansion Not often root resorption present Resorption & displacement 42
  • 43.
    Odontogenic keratocyst Ameloblastoma Lesscortical expansion More cortical expansion 1st ,2nd or 3rd decades Older age Paresthesia absent Paresthesia may be present 43
  • 44.
    Odontogenic Keratocyst OdontogenicMyxoma Radiolucent –multilocular ,soap bubble appearance Radiolucent-radiopaque, tennis racket or step ladder appearance Thin septa curved ,or cicular Thin etched septa is straight always 44
  • 45.
    Odontogenic Keratocyst SimpleBone Cyst Scalloped borders mostly towards the inferior border of mandible Scalloping borders towards the crestal bone Resorption or displacement of tooth No resorption or displacement of tooth Loss of lamina dura No loss of lamina dura 45
  • 46.
    BASAL CELL NEVUSSYNDROME or GORLIN-GOLTZ SYNDROME Syndrome comprises of variety of abnormalities:- 1. B= Multiple nevoid Basal Cell Carcinomas of the skin. 2. S= Skeletal abnormalities. 3. C= Central nervous system abnormalities 4. M= Multiple odontogenic keratocyst. 5. EN= Endocrine system abnormality. 46
  • 47.
    • Clinical features:- •After 5 years of age & before 30 years. • Skin lesions- small ,flattened, flesh or brown color papules on face, trunk & neck. 47
  • 48.
    • Basal cellcarcinoma of the skin 48
  • 49.
    • Skeletal abnormalities–Bifid rib, Synostosis of ribs. 49
  • 50.
    • Multiple OKCin multiple sites of jaws. 50
  • 51.
    • Costal abnormalitiesas agenesis , deformity, kyphoscoliosis, vertebral fusion, polydactyly, shortening of metacarpals. 51
  • 52.
    • Temporal &temperoparietal bossing. 52
  • 53.
    • Minor hypertelorism. •Mild prognathism. • Calcification of falx cerebri & duramater in early life. 53
  • 54.
  • 55.
    • DIFFERENTIAL DIAGNOSIS:- •Multiple myeloma • Cherubism Basal Cell Nevus Syndrome Multiple Myeloma Multilocular radiolucencies Multiple punched out radiolucencies with corticated borders. 55
  • 56.
  • 57.
    Basal Cell NevusSyndrome Cherubism Multiple multilocular radiolucency No jaw expansion, Bilateral multilocular radioluceny. Significant jaw expansion No displacement of the teeth Pushes posterior teeth in anterior direction 57
  • 58.
    CALCIFYING EPITHELIAL ODONTOGENICCYST o Synonym- Calcifying Odontogenic cyst o Gorlin cyst. o Clinical features:- o 1st peak is 10-19 years, 2nd peak is 7th decade. o Slow-growing, painless swelling of jaw. o Expansion destroy cortical plate. o Advanced lesion--- discharge 58
  • 59.
    • On ASPIRATION:-viscous, granular, yellow fluid. • RADIOGRAPHIC INTERPRETATION:- • Location– 75% anterior to the 1st molar. Cuspid and premolar region. Sometimes manifests as pericoronal radiolucencies. • Peripheri & Shape– well defined corticated, Ill defined & irregular in cyst like lesions . 59
  • 60.
    • Internal structure:-varies usually… completely radiolucent --- small evidence of foci of calcified material . • Effects on supporting structures:- 20%-50% commonly associated with cuspid & impedes its eruption. Displacement & resorption of roots Perforation of cortical plate. 60
  • 61.
  • 62.
    • Differential Diagnosis •Dentigerous cyst • Adenomatoid odontogenic tumour • Ameloblastic fibro-odontoma 62
  • 63.
    CEOC DENTIGEROUS CYST Notevident always pericoronally Always pericoronal radiolucent Tiny fleks of calcification masses are evedent Uniform radiolucent 63