Preventing DiabetesPreventing Diabetes
Dany Zayour, MDDany Zayour, MD
Via Christi ClinicVia Christi Clinic
Diabetes and Endocrinology CenterDiabetes and Endocrinology Center
Why talk about Diabetes?Why talk about Diabetes?
 26 million americans (11.3%) have diabetes26 million americans (11.3%) have diabetes
 7 million do not know it7 million do not know it
 2 new million cases diagnosed each year2 new million cases diagnosed each year
 79 million americans have prediabetes79 million americans have prediabetes
 37 million (15%) will have diabetes in 201537 million (15%) will have diabetes in 2015
 1 in 3 adults will have diabetes in 20501 in 3 adults will have diabetes in 2050
What is prediabetes?What is prediabetes?
What is prediabetes?What is prediabetes?
 Blood sugar is higher than normal but not asBlood sugar is higher than normal but not as
high as diabeteshigh as diabetes
 Touch of sugarTouch of sugar
 Mild diabetesMild diabetes
 Prediabetes is likely to progress to diabetes in 10Prediabetes is likely to progress to diabetes in 10
years or lessyears or less
 Already started complicationsAlready started complications
How do I know if I have prediabetes?How do I know if I have prediabetes?
SymptomsSymptoms
 No signs or symptomsNo signs or symptoms
 Darkened areas of skin called acanthosis nigricansDarkened areas of skin called acanthosis nigricans
 Signs of diabetesSigns of diabetes
 Increased thirstIncreased thirst
 Frequent urinationFrequent urination
 FatigueFatigue
 Blurred visionBlurred vision
 Recurrent infectionRecurrent infection
 Tingling and numbnessTingling and numbness
 Cuts and bruises that are slow to healCuts and bruises that are slow to heal
What increases my risk for diabetesWhat increases my risk for diabetes
and should I get tested?and should I get tested?
What increases the risk of diabetes?What increases the risk of diabetes?
 Overweight or obese (BMI above 25)Overweight or obese (BMI above 25)
 Extra weight in your bellyExtra weight in your belly
 Not physically activeNot physically active
 SmokingSmoking
 Family history of type 2 diabetesFamily history of type 2 diabetes
 Gestational diabetes or baby more than 9 lbsGestational diabetes or baby more than 9 lbs
 PCOSPCOS
 Sleep fewer than 6 hrs or more than 9 hrs per daySleep fewer than 6 hrs or more than 9 hrs per day
 Race: african american, asian, HispanicRace: african american, asian, Hispanic
Are there any blood tests to diagnose prediabetes?Are there any blood tests to diagnose prediabetes?
Blood tests to diagnose prediabetesBlood tests to diagnose prediabetes
 Fasting glucoseFasting glucose
 8 hrs fast8 hrs fast
 BS 100-125 mg/dlBS 100-125 mg/dl
 Glucose tolerance testGlucose tolerance test
 Drink sugary solutionDrink sugary solution
 BS 2 hrs after that 140-199BS 2 hrs after that 140-199
 Hemoglobin A1c or HbA1cHemoglobin A1c or HbA1c
 HbA1c 5.7-6.4%HbA1c 5.7-6.4%
A1C eAGA1C eAG
%% mg/dlmg/dl
66 126126
6.56.5 140140
77 154154
7.57.5 169169
88 183183
8.58.5 197197
99 212212
9.59.5 226226
1010 240240
HbA1c and average glucose
ADA Diagnostic Criteria:ADA Diagnostic Criteria:
Normal, Diabetes, and Pre-diabetesNormal, Diabetes, and Pre-diabetes
Clinical Practice Recommendations 2010Clinical Practice Recommendations 2010
ParameterParameter NormalNormal DiabetesDiabetes Pre-diabetesPre-diabetes MethodMethod
11 Fasting PlasmaFasting Plasma
GlucoseGlucose
(mg/dl)(mg/dl)
<100<100 ≥≥126126 100–125100–125 No caloric intakeNo caloric intake
for at least 8 hfor at least 8 h
22 2-h plasma2-h plasma
glucose onglucose on
OGTT (mg/dl)OGTT (mg/dl)
<140<140 ≥≥200200 140–199140–199 WHO method: 75WHO method: 75
g glucose loadg glucose load
33 RandomRandom
plasma glucoseplasma glucose
(mg/dl)(mg/dl)
<140<140 ≥≥200200 -- with classicwith classic
symptomssymptoms
of hyperglycemiaof hyperglycemia
or crisisor crisis
44 A1CA1C
%%
<5.7<5.7 ≥≥6.56.5 5.7 – 6.45.7 – 6.4 NGSP certifiedNGSP certified
methodmethod
standardized tostandardized to
the DCCT assaythe DCCT assay
What is the treatment of prediabetes?What is the treatment of prediabetes?
Reducing risk of DiabetesReducing risk of Diabetes
 Losing 7% (5-10%) of body weightLosing 7% (5-10%) of body weight
 Decrease risk by 58%Decrease risk by 58%
 11% per year of prediabetes develop diabetes in11% per year of prediabetes develop diabetes in
the first 3 yearsthe first 3 years
DietDiet
 DietDiet
 Low in fatLow in fat
 High in fibersHigh in fibers
 Focus on fruits, vegetables and whole grainsFocus on fruits, vegetables and whole grains
 VarietyVariety
Physical activityPhysical activity
 30-60 minutes daily 5 days a week ( there are 1440 min in a day)30-60 minutes daily 5 days a week ( there are 1440 min in a day)
 Brisk daily walkingBrisk daily walking
 Ride your bikeRide your bike
 DancingDancing
 Low impact aerobic classLow impact aerobic class
 SwimmingSwimming
 Exercise while sittingExercise while sitting
 Use stairsUse stairs
 Park away from entrancePark away from entrance
MedicationsMedications
 MetforminMetformin
 ActosActos
 AcarboseAcarbose
 GLP-1 agonistsGLP-1 agonists
Alternative medicineAlternative medicine
 CinnamonCinnamon
 ChromiumChromium
 GinsengGinseng
 Prickly pear cactusPrickly pear cactus
 SoySoy
 SteviaStevia
 GymnemaGymnema
THANK YOUTHANK YOU

Preventing diabetes

  • 1.
    Preventing DiabetesPreventing Diabetes DanyZayour, MDDany Zayour, MD Via Christi ClinicVia Christi Clinic Diabetes and Endocrinology CenterDiabetes and Endocrinology Center
  • 2.
    Why talk aboutDiabetes?Why talk about Diabetes?  26 million americans (11.3%) have diabetes26 million americans (11.3%) have diabetes  7 million do not know it7 million do not know it  2 new million cases diagnosed each year2 new million cases diagnosed each year  79 million americans have prediabetes79 million americans have prediabetes  37 million (15%) will have diabetes in 201537 million (15%) will have diabetes in 2015  1 in 3 adults will have diabetes in 20501 in 3 adults will have diabetes in 2050
  • 4.
    What is prediabetes?Whatis prediabetes?
  • 5.
    What is prediabetes?Whatis prediabetes?  Blood sugar is higher than normal but not asBlood sugar is higher than normal but not as high as diabeteshigh as diabetes  Touch of sugarTouch of sugar  Mild diabetesMild diabetes  Prediabetes is likely to progress to diabetes in 10Prediabetes is likely to progress to diabetes in 10 years or lessyears or less  Already started complicationsAlready started complications
  • 6.
    How do Iknow if I have prediabetes?How do I know if I have prediabetes?
  • 7.
    SymptomsSymptoms  No signsor symptomsNo signs or symptoms  Darkened areas of skin called acanthosis nigricansDarkened areas of skin called acanthosis nigricans  Signs of diabetesSigns of diabetes  Increased thirstIncreased thirst  Frequent urinationFrequent urination  FatigueFatigue  Blurred visionBlurred vision  Recurrent infectionRecurrent infection  Tingling and numbnessTingling and numbness  Cuts and bruises that are slow to healCuts and bruises that are slow to heal
  • 10.
    What increases myrisk for diabetesWhat increases my risk for diabetes and should I get tested?and should I get tested?
  • 11.
    What increases therisk of diabetes?What increases the risk of diabetes?  Overweight or obese (BMI above 25)Overweight or obese (BMI above 25)  Extra weight in your bellyExtra weight in your belly  Not physically activeNot physically active  SmokingSmoking  Family history of type 2 diabetesFamily history of type 2 diabetes  Gestational diabetes or baby more than 9 lbsGestational diabetes or baby more than 9 lbs  PCOSPCOS  Sleep fewer than 6 hrs or more than 9 hrs per daySleep fewer than 6 hrs or more than 9 hrs per day  Race: african american, asian, HispanicRace: african american, asian, Hispanic
  • 12.
    Are there anyblood tests to diagnose prediabetes?Are there any blood tests to diagnose prediabetes?
  • 13.
    Blood tests todiagnose prediabetesBlood tests to diagnose prediabetes  Fasting glucoseFasting glucose  8 hrs fast8 hrs fast  BS 100-125 mg/dlBS 100-125 mg/dl  Glucose tolerance testGlucose tolerance test  Drink sugary solutionDrink sugary solution  BS 2 hrs after that 140-199BS 2 hrs after that 140-199  Hemoglobin A1c or HbA1cHemoglobin A1c or HbA1c  HbA1c 5.7-6.4%HbA1c 5.7-6.4%
  • 14.
    A1C eAGA1C eAG %%mg/dlmg/dl 66 126126 6.56.5 140140 77 154154 7.57.5 169169 88 183183 8.58.5 197197 99 212212 9.59.5 226226 1010 240240 HbA1c and average glucose
  • 15.
    ADA Diagnostic Criteria:ADADiagnostic Criteria: Normal, Diabetes, and Pre-diabetesNormal, Diabetes, and Pre-diabetes Clinical Practice Recommendations 2010Clinical Practice Recommendations 2010 ParameterParameter NormalNormal DiabetesDiabetes Pre-diabetesPre-diabetes MethodMethod 11 Fasting PlasmaFasting Plasma GlucoseGlucose (mg/dl)(mg/dl) <100<100 ≥≥126126 100–125100–125 No caloric intakeNo caloric intake for at least 8 hfor at least 8 h 22 2-h plasma2-h plasma glucose onglucose on OGTT (mg/dl)OGTT (mg/dl) <140<140 ≥≥200200 140–199140–199 WHO method: 75WHO method: 75 g glucose loadg glucose load 33 RandomRandom plasma glucoseplasma glucose (mg/dl)(mg/dl) <140<140 ≥≥200200 -- with classicwith classic symptomssymptoms of hyperglycemiaof hyperglycemia or crisisor crisis 44 A1CA1C %% <5.7<5.7 ≥≥6.56.5 5.7 – 6.45.7 – 6.4 NGSP certifiedNGSP certified methodmethod standardized tostandardized to the DCCT assaythe DCCT assay
  • 16.
    What is thetreatment of prediabetes?What is the treatment of prediabetes?
  • 17.
    Reducing risk ofDiabetesReducing risk of Diabetes  Losing 7% (5-10%) of body weightLosing 7% (5-10%) of body weight  Decrease risk by 58%Decrease risk by 58%  11% per year of prediabetes develop diabetes in11% per year of prediabetes develop diabetes in the first 3 yearsthe first 3 years
  • 18.
    DietDiet  DietDiet  Lowin fatLow in fat  High in fibersHigh in fibers  Focus on fruits, vegetables and whole grainsFocus on fruits, vegetables and whole grains  VarietyVariety
  • 19.
    Physical activityPhysical activity 30-60 minutes daily 5 days a week ( there are 1440 min in a day)30-60 minutes daily 5 days a week ( there are 1440 min in a day)  Brisk daily walkingBrisk daily walking  Ride your bikeRide your bike  DancingDancing  Low impact aerobic classLow impact aerobic class  SwimmingSwimming  Exercise while sittingExercise while sitting  Use stairsUse stairs  Park away from entrancePark away from entrance
  • 20.
    MedicationsMedications  MetforminMetformin  ActosActos AcarboseAcarbose  GLP-1 agonistsGLP-1 agonists
  • 21.
    Alternative medicineAlternative medicine CinnamonCinnamon  ChromiumChromium  GinsengGinseng  Prickly pear cactusPrickly pear cactus  SoySoy  SteviaStevia  GymnemaGymnema
  • 25.

Editor's Notes

  • #15 To facilitate patient-doctor communication regarding glucose levels, the A1c values are now being reported as eAG, After standardization of A1c in the ADAG trial using CGMs for 6 months, and determining an accurate correlation with average glucose levels.. All labs now report…