Ptosis
BY
ANAM
SEHREEN
DOCTOR OF
OPTOMETRY
PTOSIS
Ptosis is an abnormally low
position of the upper lid.
Grading and severity
Normally upper eyelid cover 1/6th of cornea
 Mild < or = 2mm
 Moderate = 3mm
 Severe > 4mm
FUNCTIONAL ANATOMY
Levator Palpebral Superioris (LPS):
 Is the primary muscle responsible for lid elevation.
 It arises from the back of the orbit and extends forwards
over the cone of eye muscles.
 It inserts into the eyelid and the tarsal plate, a fibrous
semicircular structure which gives the upper eyelid its
shape.
 The LPS is supplied by the superior division of the
oculomotor nerve.
Muller’s Muscle:
 The way that the LPS attaches to the tarsal plate is
modified by the underlying Müller's muscle.
 This involuntary muscle, comprising sympathetically
innervated smooth muscle
 Has the capacity to 'tighten' the attachment and so raise
the lid a few millimetres.
Frontalis and Orbicularis Oculi muscles:
 Both muscles supplied by the facial nerve.
 Frontalis contraction helps to elevate the lid by acting
indirectly on the surrounding soft tissues, while orbicularis
oculi contraction depresses the eyelid.
CLASSIFICATION
It may be
 Acquired
 Congenital
Acquired
1) Neurogenic
2) Myogenic
3) Aponeurotic
4) Mechanical
5) Neurotoxic
1). NEUROGENIC
It caused by an innervational defect such as 3rd nerve
paresis and Horner's Syndrome.
 3rd nerve misdirection syndrome
• Rare, unilateral
• Aberrant regeneration following acquired 3rd nerve palsy
• Bizarre movements of upper lid accompany eye
movements
• Pupil is occasionally involved
• Right ptosis primary position
• Worse on right gaze
• Normal on left gaze
 HORNER SYNDROME:
It is a relatively rare disorder characterized by:
 A constricted pupil (miosis)
 Drooping of the upper eyelid (ptosis)
 Absence of sweating of the face (anhidrosis)
 Sinking of the eyeball into the bony cavity that protects
the eye (enophthalmos)
2). MAYOGENIC:
 Caused by the myopathy of the levator muscle itself or
by the impairment of the transmission of impulses at the
neuro muscular junction
 Acquired myogenic occurs in myasthenia gravis
myotonic dystrophy and progressive external
ophthalmoplegia.
3). APONEURATIC
Caused by a defect in
the levator aponeurosis
Involutional ptosis
Aponeuratic ptosis also called senile or involutional ptosis, is the
most common type of acquired ptosis. It is caused by a disinsertion
or dehiscence of the levator aponeurosis from the tarsus.
 Clinical exam reveals a high lid crease, generally good levator
function and typically worsening of the ptosis on downgaze.
 Such patients tend to do well with surgical correction which
involves advancement and reattachment of the levator
aponeurosis to the anterior tarsal surface.
4). MECHANICAL:
With mechanical ptosis, the eyelid is weighed down by
excessive skin or a mass.
 Traumatic ptosis is caused by an injury to the eyelid.
Either due to an accident or other eye trauma.
 This injury compromises or weakens the levator muscle
CONGENITAL
1) Simple congenital ptosis
2) Congenital ptosis
3) Congenital synkinetic ptosis
4) Blepharophimosis Syndrome
1). Simple congenital ptosis
Not associated with any anomaly
2). Congenital ptosis
 It results from a failure of neuronal migration or development with
muscular sequalae.
 Superior Rectus weakness
 Compensatory Chin elevation
 Absent upper lid crease
 In downward gaze the ptotic lid is higher then the normal because
of poor relaxation of the levator function
3). Congenital Synkinetic ptosis
 Marcus Gun Jaw winking Ptosis
MARCUS GUN JAW WINKING PTOSIS
About 5% of the congenital cases are associated with the Marcus
gun jaw winking phenomenon.
 Retraction of the ptotic lid in conjunction with stimulation of the
ipsilateral
 Pterygoid muscle by chewing, sucking, opening the mouth
 Less common stimuli to winking include jaw protrusion, smiling,
swallowing and clenching of teeth
 Jaw winking does not improve with age
 Exact aetiology is unclear
PSEUDOPTOSIS
False impression of the ptosis which may be caused by:
 LACK OF SUPPORT
 Lack of support of the lids by the globe ma be due to the orbital
volume deficient associated with enophthalmos.
 CONTRALATERAL LID RETRACTION
 Which is detected by comparing the levels of upper eyelids the
margin of the upper lid mat cover the superior 2mm of cornea
 IPSILATERAL HYPOTROPIA
 Upper lid follows the globe downward
 BROW PTOSIS
• Due to excessive skin on the brow
SIGN AND SYMPTOMS OF PTOSIS
 Dropping eyelid
 Raising of the eyebrows to lift the eyelids for better
vision
 Watery eye
 Tilting the head
 Aching in and around the eyes
 Looking tired
 Double vision
 Difficulty closing the eyes or blinking
EVALUATION OF PTOSIS:
 History:
 Age of onset
 Duration
 One/both eye
 Diurnal variability
 Associated history:
o Diplopia
o Dysphagia
o Muscle weakness
 Vision
 Associated with:
 Jaw movements
 Abnormal ocular movements
 Abnormal head posture
 History of:
 Trauma or previous surgery
 Poisoning
 Use of steroid drops
 Any reaction with anesthesia
 Bleeding tendency
 Previous photographs may prove to be of great help.
 Is there a family history of ptosis or of other muscle
weakness?
OCULAR EXAMINATION
Normal position of eyelids:
 The normal upper eyelid in primary position
 Crosses the iris b/w the limbus (junction of the iris and sclera)
and the pupil
 Usually 1 mm to 2 mm below the limbus
 The lower lid touches or crosses slightly above the limbus.
 Normally there is no sclera showing above the iris.
Palpebral fissures:
It is normally 9 mm to 12 mm from upper to lower lid margin
Visual Acuity:
Best-corrected visual acuity should be assessed to record any
amblyopia if present, especially in cases of congenital ptosis.
PUPILLARY EXAMINATION
 TO diagnosis Horner’s syndrome
 Involvement in a case of third nerve palsy
 TOTAL UNILATERAL PTOSIS
 Complete third nerve palsy.
 MILD TO MODERATE PTOSIS
 Horner's syndrome
 partial third nerve palsy.
 MILD TO MODERATE BILATERAL PTOSIS
 Neuromuscular disorders such as MG
 Muscular dystrophy
 Ocular myopathy
MEASUREMENTS
1) Margin reflex distance
2) Vertical fissure height
3) LPS action
4) Lid crease level
5) Lid level on down gaze
1). MARGIN REFLEX DISTANCE:
Margin-to-reflex distance 1 (MRD1)
• When light is thrown on the cornea, a reflection
occurs.
• The distance from the central pupillary light reflex to
the upper eyelid margin with the eye in primary gaze.
• If the margin is above the light reflex the MRD 1 is a
+ve value.
• If the lid margin is below the corneal reflex in cases of
very severe ptosis the MRD 1 would be a –ve value.
2). VERTICAL FISSURE HEIGHT
 The distance between the upper and lower eyelid in vertical
alignment with the center of the pupil in primary gaze, with the
patient’s brow relaxed.
Normal – 9-10mm in primary gaze
 Should be seen in up gaze, down gaze and primary gaze
 Amount of ptosis = difference in palpebral apertures in unilateral
ptosis or Difference from normal in bilateral ptosis
3). LEVATOR FUNCTION ASSESSMENT
 It is determined by the lid excursion caused by LPS muscle
(Burke’s method).
 Patient is asked to look down and thumb of one hand is placed
firmly against the eyebrow of the patient (to block the action of
frontalis muscle) by the examiner.
 Then the patient is asked to look up and the amount of upper lid
excursion is measured with a ruler held in the other hand by the
examiner.
 Levator function is graded as follows:
 Normal 15 mm
 Good 8 mm or more
 Fair 5-7 mm
 Poor 4 mm or less
INVESTIGATION
 Serum acetylcholine receptor assay
 Tensilon test
 EMG
 ECG
 ERG
 T3, T4, TSH
TREATMENT
CONGENITAL PTOSIS
Almost always surgical treatment
AQUIRED PTOSIS
 Treat the underlying cause
 Surgey
 Fasanella servant operation
 Levator resection
 Frontalis sling operation
FASANELLA-SERVAT PROCEDURE
 Indicated for mild ptosis(1.5-2mm) with good levator
function
LEVATOR RESECTION
 Indicated for any ptosis provided levator function is at least 5mm.
 Contraindicated in patients having severe ptosis with poor
levator function.
FRONTALIS BROW SUSPENSION
 Used in severe ptosis with poor levator function (4 mm or less).
 The tarsal plate is suspended from the frontalis muscle with a
sling consisting of autologous fascia lata or non absorbable
material such as prolene or silicon.
 Marcus Gunn jaw-winking syndrome
PTOSIS.pptx

PTOSIS.pptx

  • 2.
  • 3.
    PTOSIS Ptosis is anabnormally low position of the upper lid. Grading and severity Normally upper eyelid cover 1/6th of cornea  Mild < or = 2mm  Moderate = 3mm  Severe > 4mm
  • 4.
    FUNCTIONAL ANATOMY Levator PalpebralSuperioris (LPS):  Is the primary muscle responsible for lid elevation.  It arises from the back of the orbit and extends forwards over the cone of eye muscles.  It inserts into the eyelid and the tarsal plate, a fibrous semicircular structure which gives the upper eyelid its shape.  The LPS is supplied by the superior division of the oculomotor nerve.
  • 5.
    Muller’s Muscle:  Theway that the LPS attaches to the tarsal plate is modified by the underlying Müller's muscle.  This involuntary muscle, comprising sympathetically innervated smooth muscle  Has the capacity to 'tighten' the attachment and so raise the lid a few millimetres. Frontalis and Orbicularis Oculi muscles:  Both muscles supplied by the facial nerve.  Frontalis contraction helps to elevate the lid by acting indirectly on the surrounding soft tissues, while orbicularis oculi contraction depresses the eyelid.
  • 6.
    CLASSIFICATION It may be Acquired  Congenital Acquired 1) Neurogenic 2) Myogenic 3) Aponeurotic 4) Mechanical 5) Neurotoxic
  • 7.
    1). NEUROGENIC It causedby an innervational defect such as 3rd nerve paresis and Horner's Syndrome.  3rd nerve misdirection syndrome • Rare, unilateral • Aberrant regeneration following acquired 3rd nerve palsy • Bizarre movements of upper lid accompany eye movements • Pupil is occasionally involved • Right ptosis primary position • Worse on right gaze • Normal on left gaze
  • 8.
     HORNER SYNDROME: Itis a relatively rare disorder characterized by:  A constricted pupil (miosis)  Drooping of the upper eyelid (ptosis)  Absence of sweating of the face (anhidrosis)  Sinking of the eyeball into the bony cavity that protects the eye (enophthalmos)
  • 9.
    2). MAYOGENIC:  Causedby the myopathy of the levator muscle itself or by the impairment of the transmission of impulses at the neuro muscular junction  Acquired myogenic occurs in myasthenia gravis myotonic dystrophy and progressive external ophthalmoplegia.
  • 10.
    3). APONEURATIC Caused bya defect in the levator aponeurosis Involutional ptosis Aponeuratic ptosis also called senile or involutional ptosis, is the most common type of acquired ptosis. It is caused by a disinsertion or dehiscence of the levator aponeurosis from the tarsus.  Clinical exam reveals a high lid crease, generally good levator function and typically worsening of the ptosis on downgaze.  Such patients tend to do well with surgical correction which involves advancement and reattachment of the levator aponeurosis to the anterior tarsal surface.
  • 11.
    4). MECHANICAL: With mechanicalptosis, the eyelid is weighed down by excessive skin or a mass.  Traumatic ptosis is caused by an injury to the eyelid. Either due to an accident or other eye trauma.  This injury compromises or weakens the levator muscle
  • 12.
    CONGENITAL 1) Simple congenitalptosis 2) Congenital ptosis 3) Congenital synkinetic ptosis 4) Blepharophimosis Syndrome 1). Simple congenital ptosis Not associated with any anomaly
  • 13.
    2). Congenital ptosis It results from a failure of neuronal migration or development with muscular sequalae.  Superior Rectus weakness  Compensatory Chin elevation  Absent upper lid crease  In downward gaze the ptotic lid is higher then the normal because of poor relaxation of the levator function 3). Congenital Synkinetic ptosis  Marcus Gun Jaw winking Ptosis
  • 14.
    MARCUS GUN JAWWINKING PTOSIS About 5% of the congenital cases are associated with the Marcus gun jaw winking phenomenon.  Retraction of the ptotic lid in conjunction with stimulation of the ipsilateral  Pterygoid muscle by chewing, sucking, opening the mouth  Less common stimuli to winking include jaw protrusion, smiling, swallowing and clenching of teeth  Jaw winking does not improve with age  Exact aetiology is unclear
  • 15.
    PSEUDOPTOSIS False impression ofthe ptosis which may be caused by:  LACK OF SUPPORT  Lack of support of the lids by the globe ma be due to the orbital volume deficient associated with enophthalmos.  CONTRALATERAL LID RETRACTION  Which is detected by comparing the levels of upper eyelids the margin of the upper lid mat cover the superior 2mm of cornea  IPSILATERAL HYPOTROPIA  Upper lid follows the globe downward  BROW PTOSIS • Due to excessive skin on the brow
  • 17.
    SIGN AND SYMPTOMSOF PTOSIS  Dropping eyelid  Raising of the eyebrows to lift the eyelids for better vision  Watery eye  Tilting the head  Aching in and around the eyes  Looking tired  Double vision  Difficulty closing the eyes or blinking
  • 18.
    EVALUATION OF PTOSIS: History:  Age of onset  Duration  One/both eye  Diurnal variability  Associated history: o Diplopia o Dysphagia o Muscle weakness  Vision
  • 19.
     Associated with: Jaw movements  Abnormal ocular movements  Abnormal head posture  History of:  Trauma or previous surgery  Poisoning  Use of steroid drops  Any reaction with anesthesia  Bleeding tendency  Previous photographs may prove to be of great help.  Is there a family history of ptosis or of other muscle weakness?
  • 20.
    OCULAR EXAMINATION Normal positionof eyelids:  The normal upper eyelid in primary position  Crosses the iris b/w the limbus (junction of the iris and sclera) and the pupil  Usually 1 mm to 2 mm below the limbus  The lower lid touches or crosses slightly above the limbus.  Normally there is no sclera showing above the iris. Palpebral fissures: It is normally 9 mm to 12 mm from upper to lower lid margin Visual Acuity: Best-corrected visual acuity should be assessed to record any amblyopia if present, especially in cases of congenital ptosis.
  • 21.
    PUPILLARY EXAMINATION  TOdiagnosis Horner’s syndrome  Involvement in a case of third nerve palsy  TOTAL UNILATERAL PTOSIS  Complete third nerve palsy.  MILD TO MODERATE PTOSIS  Horner's syndrome  partial third nerve palsy.  MILD TO MODERATE BILATERAL PTOSIS  Neuromuscular disorders such as MG  Muscular dystrophy  Ocular myopathy
  • 22.
    MEASUREMENTS 1) Margin reflexdistance 2) Vertical fissure height 3) LPS action 4) Lid crease level 5) Lid level on down gaze
  • 23.
    1). MARGIN REFLEXDISTANCE: Margin-to-reflex distance 1 (MRD1) • When light is thrown on the cornea, a reflection occurs. • The distance from the central pupillary light reflex to the upper eyelid margin with the eye in primary gaze. • If the margin is above the light reflex the MRD 1 is a +ve value. • If the lid margin is below the corneal reflex in cases of very severe ptosis the MRD 1 would be a –ve value.
  • 25.
    2). VERTICAL FISSUREHEIGHT  The distance between the upper and lower eyelid in vertical alignment with the center of the pupil in primary gaze, with the patient’s brow relaxed. Normal – 9-10mm in primary gaze  Should be seen in up gaze, down gaze and primary gaze  Amount of ptosis = difference in palpebral apertures in unilateral ptosis or Difference from normal in bilateral ptosis
  • 26.
    3). LEVATOR FUNCTIONASSESSMENT  It is determined by the lid excursion caused by LPS muscle (Burke’s method).  Patient is asked to look down and thumb of one hand is placed firmly against the eyebrow of the patient (to block the action of frontalis muscle) by the examiner.  Then the patient is asked to look up and the amount of upper lid excursion is measured with a ruler held in the other hand by the examiner.  Levator function is graded as follows:  Normal 15 mm  Good 8 mm or more  Fair 5-7 mm  Poor 4 mm or less
  • 27.
    INVESTIGATION  Serum acetylcholinereceptor assay  Tensilon test  EMG  ECG  ERG  T3, T4, TSH
  • 28.
    TREATMENT CONGENITAL PTOSIS Almost alwayssurgical treatment AQUIRED PTOSIS  Treat the underlying cause  Surgey  Fasanella servant operation  Levator resection  Frontalis sling operation
  • 31.
    FASANELLA-SERVAT PROCEDURE  Indicatedfor mild ptosis(1.5-2mm) with good levator function
  • 32.
    LEVATOR RESECTION  Indicatedfor any ptosis provided levator function is at least 5mm.  Contraindicated in patients having severe ptosis with poor levator function.
  • 33.
    FRONTALIS BROW SUSPENSION Used in severe ptosis with poor levator function (4 mm or less).  The tarsal plate is suspended from the frontalis muscle with a sling consisting of autologous fascia lata or non absorbable material such as prolene or silicon.  Marcus Gunn jaw-winking syndrome