RATIONAL USE OF DRUGS
Right Patient
Right Drug
Right Dose
Right Route
Right Time
Right Person
Sreenu Thalla
Assistant Professor
Department of Pharmacology
Definition
“ Prescribing right drug, in adequate dose for the sufficient duration
and appropriate to the clinical needs of the patient at lowest cost ”.
• Rational drug use attained more significance nowadays in terms of
medical, socio economical and legal aspect.
• The concept of rational drug use is old, as evident by the statement
made by the Alexandrian physician Herophilus 300 B.C that is “
Medicines are nothing in themselves but are the very hands of god if
employed with reason and prudence .”
The Rational Use of Drugs Demands
 The appropriate drug to be prescribed.
 It is to be taken in the right dose.
 It is to be taken at the right intervals and for right length of time.
 Administered by the right route of administration.
 It should be effective.
 It should be of acceptable quality.
 It should be safe.
 Available when needed.
 At a price can afford.
Factors that have led sudden realization for
Rational Drug Use
Drug explosion
• Increase in the number of drugs available has incredibly
complicated the choice of appropriate drug for particular indication.
Efforts to prevent the development of resistance
• Irrational use of drugs may lead to the premature demise of highly
efficacious and life saving new antimicrobial drug due to
development of resistance.
Growing awareness
• Today, the information about drug development, it’s uses and
adverse effects travel from one end of the planet to the other end
with amazing speed through various media.
Increased cost of the treatment
• Increase in cost of the drug increases economic burden on the
public as well as on the government.
• This can be reduced by rational drug use.
Consumer protection Act. (CPA)
• Extension of CPA in medical profession may restrict the irrational
use of drugs.
ASPECTS OF IRRATIONAL DRUG USE
Diagnosis
 Inadequate examination of the patient
 Incomplete communication between patient and doctor
 Lack of documented medical history
 Inadequate lab resources
Prescribing
 Extravagant prescribing
 Incorrect prescribing
 Multiple prescribing/ers
Dispensing
 Incorrect interpretation of the prescription
 Inaccurate counting, compounding or pouring
 Inadequate labeling
 Packaging - Poor quality packaging materials
Patient adherence
 Inadequate verbal instructions
 Inadequate follow-up/support of patients
 Treatment that do not consider the patient’s beliefs,
environment or culture
Irrational Medicine Use
 Use of too many medicines per patient i.e polypharmacy
 Inappropriate use of antimicrobials, often in inadequate dosage for
non-bacterial infections
 Overuse of injections when oral formulations would be more
appropriate
 Failure to prescribe in accordance with clinical guidelines
 Inappropriate self-medication.
Rational Drugss Use in community Pharmacy

Rational Drugss Use in community Pharmacy

  • 1.
    RATIONAL USE OFDRUGS Right Patient Right Drug Right Dose Right Route Right Time Right Person Sreenu Thalla Assistant Professor Department of Pharmacology
  • 2.
    Definition “ Prescribing rightdrug, in adequate dose for the sufficient duration and appropriate to the clinical needs of the patient at lowest cost ”. • Rational drug use attained more significance nowadays in terms of medical, socio economical and legal aspect. • The concept of rational drug use is old, as evident by the statement made by the Alexandrian physician Herophilus 300 B.C that is “ Medicines are nothing in themselves but are the very hands of god if employed with reason and prudence .”
  • 3.
    The Rational Useof Drugs Demands  The appropriate drug to be prescribed.  It is to be taken in the right dose.  It is to be taken at the right intervals and for right length of time.  Administered by the right route of administration.  It should be effective.  It should be of acceptable quality.  It should be safe.  Available when needed.  At a price can afford.
  • 4.
    Factors that haveled sudden realization for Rational Drug Use Drug explosion • Increase in the number of drugs available has incredibly complicated the choice of appropriate drug for particular indication. Efforts to prevent the development of resistance • Irrational use of drugs may lead to the premature demise of highly efficacious and life saving new antimicrobial drug due to development of resistance. Growing awareness • Today, the information about drug development, it’s uses and adverse effects travel from one end of the planet to the other end with amazing speed through various media.
  • 5.
    Increased cost ofthe treatment • Increase in cost of the drug increases economic burden on the public as well as on the government. • This can be reduced by rational drug use. Consumer protection Act. (CPA) • Extension of CPA in medical profession may restrict the irrational use of drugs.
  • 6.
    ASPECTS OF IRRATIONALDRUG USE Diagnosis  Inadequate examination of the patient  Incomplete communication between patient and doctor  Lack of documented medical history  Inadequate lab resources Prescribing  Extravagant prescribing  Incorrect prescribing  Multiple prescribing/ers
  • 7.
    Dispensing  Incorrect interpretationof the prescription  Inaccurate counting, compounding or pouring  Inadequate labeling  Packaging - Poor quality packaging materials Patient adherence  Inadequate verbal instructions  Inadequate follow-up/support of patients  Treatment that do not consider the patient’s beliefs, environment or culture
  • 8.
    Irrational Medicine Use Use of too many medicines per patient i.e polypharmacy  Inappropriate use of antimicrobials, often in inadequate dosage for non-bacterial infections  Overuse of injections when oral formulations would be more appropriate  Failure to prescribe in accordance with clinical guidelines  Inappropriate self-medication.