The document summarizes Rwanda's experience in consolidating its HIV/AIDS programs and projects under a centralized organization. It describes how between 1987-2000 Rwanda established separate organizations to coordinate its multi-sectoral HIV response and biomedical research initiatives. In 2011, in an effort to improve aid effectiveness, Rwanda consolidated its many HIV project management units into a newly formed Rwanda Biomedical Centre, which absorbed all related institutions and programs under one organization. This centralized the country's HIV coordination and clinical services while aiming to reduce management burdens and improve capacity across the health system.