This document discusses spine mobilization and manipulation techniques. It defines mobilization and manipulation as skilled passive movements applied to joints and soft tissues. Manipulation involves high velocity, low amplitude movements while mobilization can involve oscillations of varying amplitudes. The effects of manipulation include mechanical, neurophysiological, and psychological impacts. Mechanical effects involve restoring tissue extensibility and range of motion. Neurophysiological effects occur through stimulation of mechanoreceptors and descending pain pathways in the central nervous system. Psychological effects involve reducing pain and anxiety through reassurance. Clinical decision making involves considering factors like joint mobility, pain response, and targeted treatment effects when selecting techniques.