By- Gursimrat Singh Chhabra
Department of Anatomy
Aiims Rishikesh
Moderator- Dr. Vivek Mishra
Learning Objectives
 Definition
 Causes and Risk Factors
 Symptoms
 Clinical Examination and Investigation
 Treatment
Definition
 Rare condition caused by
a combination of 4 heart
defect that are present at
birth which include-
1. Pulmonary Stenosis
2. Ventricular Septum
Defect
3. Overriding of Aorta
4. Right Ventricular
Hypertrophy
Risk Factors
 Poor maternal nutrition
 Viral illness during pregnancy
 Parent having tetralogy of fallot
 Children born to mother with Polyketonuria
 Presence of down syndrome
Causes
 Abnormality of the conotruncal region
 Unequal division of the conus resulting
from Anterior displacement of conotruncal
septum.
 Defect in bulbus cordis and truncus
arteriosus.
Sign and Symptoms
 Cyanosis
 Shortness of breath
 Clubbing of fingers
 Poor weight gain
 Tiring easily
 Irritability
Tet Spell
 Babies with TOF
suddenly develop deep
blue skin, nails and lips
after crying or feeding.
 They instinctively
squat when they are
short of breath to
increase blood flow to
the lungs.
Clinical Examination
 General-
1. Central Cyanosis
2. Clubbing
 Palpation-
1. Systolic thrill
 Auscultation-
1. Single S2
2. Pansystolic Murmur
3. Ejection click
Investigation
 ECG- Sign of Right Axis Deviation Right Ventricular
Hypertrophy
 Chest X-Ray- Boot shaped heart
 Echocardiogram-
Treatment
 For Cyanotic Spell-
1. Knee Chest position
2. Morphine sulphate
3. Vasoconstrictor
4. Oxygen therapy
5. Normal saline
6. Beta blockers
Surgical Method
 Modified Blalock Taussing Shunt-
Subclavian Artery – Pulmonary Artery anastmosis
 Pott’s Shunt-
Descending Aorta – Pulmonary Artery anastmosis
 Waterston Shunt-
Ascending Aorta – Right pulmonary Artery
anastmosis
Take Home Message
OTHER CONGENITAL HEART
DISORDER
Patent Ductus Arteriosus
 Patent ductus
arteriosus (PDA) is a
condition wherein
the ductus
arteriosus fails to
close after birth.
Ectopia Cordis
 Failure of the
embryo to close the
ventral body wall.
Aortic Valvular Stenosis
 Narrowing of the
aortic valve opening.
 Only pinhole opening
remains
 Blood flow restricted
L V Aorta
References
 Langman’s Medical embryology- 13th edition
 www.myoclinic.org
 www.teachmepeadtrics.com
 www.eclinicalwork.adam.com
 www.ultrasoundlink.net
 www.radiopedia.org
Tetralogy of fallot

Tetralogy of fallot

  • 1.
    By- Gursimrat SinghChhabra Department of Anatomy Aiims Rishikesh Moderator- Dr. Vivek Mishra
  • 2.
    Learning Objectives  Definition Causes and Risk Factors  Symptoms  Clinical Examination and Investigation  Treatment
  • 3.
    Definition  Rare conditioncaused by a combination of 4 heart defect that are present at birth which include- 1. Pulmonary Stenosis 2. Ventricular Septum Defect 3. Overriding of Aorta 4. Right Ventricular Hypertrophy
  • 5.
    Risk Factors  Poormaternal nutrition  Viral illness during pregnancy  Parent having tetralogy of fallot  Children born to mother with Polyketonuria  Presence of down syndrome
  • 6.
    Causes  Abnormality ofthe conotruncal region  Unequal division of the conus resulting from Anterior displacement of conotruncal septum.  Defect in bulbus cordis and truncus arteriosus.
  • 7.
    Sign and Symptoms Cyanosis  Shortness of breath  Clubbing of fingers  Poor weight gain  Tiring easily  Irritability
  • 8.
    Tet Spell  Babieswith TOF suddenly develop deep blue skin, nails and lips after crying or feeding.  They instinctively squat when they are short of breath to increase blood flow to the lungs.
  • 9.
    Clinical Examination  General- 1.Central Cyanosis 2. Clubbing  Palpation- 1. Systolic thrill  Auscultation- 1. Single S2 2. Pansystolic Murmur 3. Ejection click
  • 10.
    Investigation  ECG- Signof Right Axis Deviation Right Ventricular Hypertrophy
  • 11.
     Chest X-Ray-Boot shaped heart
  • 12.
  • 13.
    Treatment  For CyanoticSpell- 1. Knee Chest position 2. Morphine sulphate 3. Vasoconstrictor 4. Oxygen therapy 5. Normal saline 6. Beta blockers
  • 14.
    Surgical Method  ModifiedBlalock Taussing Shunt- Subclavian Artery – Pulmonary Artery anastmosis  Pott’s Shunt- Descending Aorta – Pulmonary Artery anastmosis  Waterston Shunt- Ascending Aorta – Right pulmonary Artery anastmosis
  • 16.
  • 17.
  • 18.
    Patent Ductus Arteriosus Patent ductus arteriosus (PDA) is a condition wherein the ductus arteriosus fails to close after birth.
  • 19.
    Ectopia Cordis  Failureof the embryo to close the ventral body wall.
  • 20.
    Aortic Valvular Stenosis Narrowing of the aortic valve opening.  Only pinhole opening remains  Blood flow restricted L V Aorta
  • 21.
    References  Langman’s Medicalembryology- 13th edition  www.myoclinic.org  www.teachmepeadtrics.com  www.eclinicalwork.adam.com  www.ultrasoundlink.net  www.radiopedia.org

Editor's Notes