Mature food companies must engage in aggressive cost reduction, portfolio simplification, and innovative growth strategies to enhance shareholder value. An analysis of twelve major U.S. packaged food companies highlights a divide between lower-performing firms, which have struggling margins and minimal growth, and higher-performing companies, which achieve better operational returns through improved growth and margin management. To thrive, companies should embrace a combined approach focusing on raising margins, rationalizing their portfolios, and pursuing targeted growth initiatives.