Vaccines

Vaccines

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  Vaccines
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  Immunization Delivery systems &Antigen d.s 1 4 Contents: Active & Passive immunization2 Formulation of vaccines3 Challenges5
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  What is Immunization? Activeimmunization Passive immunization
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  1st Active immunization:
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  Types of Vaccines:
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  Live attenuated vaccines:
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  Inactivated or 'killed'vaccines:
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  Recombinant sub-unit envelope vaccines:
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  Recombinant vectored vaccines:
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  DNA vaccines :
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  Toxoid vaccines:
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  Conjugate vaccines :
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  New…!!!! Edible Vaccines: Strategy of production Mode of Action
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  2ndPassive immunization:
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  Formulation of Vaccines: AdditivesFormulation Steps •Suspending fluids •Preservatives & stabilizers •Adjuvants • Component Processing • Aseptic Formulation • Filtration • Filling Prefilled Syringes Cartridges Freeze-Dried Vials • Packaging and 100% Inspection
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  Typical Aseptic Formulation ofVaccine To Filling Sterile, Adjuvant Suspension Final Formulation Aseptic Connections Redundant Sterile Filtration CLASS 100 Typically Autoclaved Pre-Sterilized Excipients pH Adjust Conjugate Manifold, gravity fed bags or cans Filtration CLASS 10,000 Buffer Pooling Tank
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  Delivery Systems: Parenteral RouteNon-Parenteral Route
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  Antigen delivery systems:
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  Thank You 