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![●Azardirachta indica (Neem) नीम
●In sheep, neem water extracts was 53.72% effective
against Haemonchus contortus [Rob et al.,2004].
Haemonchu worm Haemonchu egg
Anaemia due to Haemonchu](https://image.slidesharecdn.com/indegiosdeug-200503023621/75/Veterinary-indigenous-medicine-Dr-Jibachha-Sah-M-V-Sc-Lecturer-19-2048.jpg)
![●Areca catechu ( Betel nut) सुपारी
●Betel nut has showed better results and an in vivo
anthelmintic effect at 30 gm/20 kg body weight against
roundworms and tapeworms of small ruminants and
native chickens (Peng et al. 2015).
● Arecholine, active ingredient found in betel nut, inhibits
the gamma amino benzoic acid that causes paralysis of
the helminths [Orazaga et al., 2017].](https://image.slidesharecdn.com/indegiosdeug-200503023621/75/Veterinary-indigenous-medicine-Dr-Jibachha-Sah-M-V-Sc-Lecturer-22-2048.jpg)
![References
Chopade VV, Tankar AN, Pande VV, Tekade AR, Gowekar NM, Bhandari SR, Khandake SN. [2008] Pongamia pinnata: Phytochemical
constituents, traditional uses and pharmacological properties: A review. Int J Green Pharm; 2: 72- 75.
Peng W, Liu YJ, Wu N, Sun T, He XY, Gao YX, et al. Areca catechu L. (Arecaceae): a review of its traditional uses, botany,
phytochemisty, pharmacology and toxicology. J Ethno Pharmacol 2015; 164:340–56; h
Orazaga MSI, Orazaga BP. Efficay of Ipil-ipil (Leucaena leucocephala), Betel Nut (Arecha catechu) and Papaya (Carica papaya) seeds
against roundworms of Darag Native Chicken. Philippine J Vet Anim Sci 2017. 43(1):33–7
Rob S, Mostofa M, Awal MA, Shahiduzzaman M, Sardar SA. Comparative efficacy of albendazole (Endokil) and neem (Azadirachta
indica) leaves extract against hemonchosis in sheep. Progress Agr 2004; 15(2):33–9.
Subhedar S, Goswami P, Rana N, Gupta A, Shukla P. Herbal alternatives: anthelmintic activity of Punica granatum (Pomegranate) Int J
Drug Discov Herb Res. 2011;1(3):150–152.
Okeniyi, J.A., Ogunlesi, T.A., Oyelami, O.A. and Adeyemi, L.A. (2007). Effectiveness of dried Carica papaya seeds against human
intestinal parasitosis: A pilot study. Journal of Medicine and Food. 10, 194-196
Maulidila Briliana Agarti, Muhammad Ibrahim, Salma Alfiana, Sekentya Mauridha Sasturi, EM Sutrisna,2017. THE ACTIVITIES OF
ANTHELMINTIC INFUSA OF PAPAYA SEEDS (CARICA PAPAYA L.) AGAINST WORMS ASCARIS SUUM (STUDY IN VITRO) J.Bio.Innov 6
(5), pp: 659-663,)](https://image.slidesharecdn.com/indegiosdeug-200503023621/75/Veterinary-indigenous-medicine-Dr-Jibachha-Sah-M-V-Sc-Lecturer-23-2048.jpg)
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Veterinary indigenous medicine-Dr.Jibachha Sah,M.V.Sc,Lecturer
- 1. VETERINARY INDIGENOUS DRUGS (antiseptics,antifungals, anthelminithics, arthropode repellants) Dr. Jibachha Sah M.V.Sc, Lecturer, College of Veterinary Science, NPI, Bhojad, Chitwan, Nepal [email protected],00977-9845024121
- 2. INDIGENOUS DRUGS INTRODUCTION: ●Indigenous drugs( Ethno medicine) refer to pharmacologically active principles primarily obtained from the medicinal plants with proven therapeutic value. ●A large number of medicinal plants have been recognized to possess therapeutic value in the treatment of a variety of diseases. ●The medicinal plants contain pharmacologically active principles such as alkaloids, glycosides, resins, tannins, fixed oils, volatile oils etc.
- 6. INDIGENOUS ANTIBACTERIAL/ANTISEPTIC AGENTS ●Curcumalonga (Turmeric) बेसार ● Azadirachta indica (Neem) नीम ● Allium sativum (Lasun) (लसुन) ● Ocimum sanctum(Tulsi) 'तुलसी' ● Zingiber officinalis (Ginger) - अदुवा
- 7. •Curcuma longa (Turmeric)बेसार :It contains a yellow-colored chemical called curcumin, which is often used to color foods and cosmetics. INDIGENOUS ANTIBACTERIAL/ANTISEPTIC AGENTS Turmeric is commonly used for conditions involving pain and inflammation, such as osteoarthritis. It is also used for hay fever, depression, high cholesterol, a type of liver disease, and itching.
- 9. •Azadirachta indica-Neem (नीम) Neemleaves to cure skin diseases such as boils, ulcers, eczema, and ring worm. Pastes and extracts from Neem trees have also proven effective in treating various skin fungus conditions, including athlete's foot and lesions in the mouth and vagina. Neem oil Cure dermatitis, maggot wound
- 10. •Allium sativum (लसुन) Beingan antiseptic and anti- dermatophytic, it is used in different skin diseases.
- 11. •Ocimum sanctum(Tulsi) 'तुलसी' Forthe treatment of bronchitis, malaria, diarrhea, dysentery, skin disease, arthritis, eye diseases, insect bites and so on. Tulsi (Ocimum tenuiflorum) and Turmeric (Curcuma longa) for Bacterial Infection Treatment
- 12. •Zingiber officinalis (Ginger)- अदुवा The antioxidants in ginger can be used to help preserve skin's collagen, making it an all-natural ingredient for anti-aging routines. After Ginger bath Dermatophytosis
- 13. INDIGENOUS ANTIFUNGAL AGENTS ●Curcumalonga (Turmeric) बेसार ● Pongamia glabra (Karanj) करंज ● Azadirachta indica-Neem (नीम) ● Cassia alata((दादमुददन)
- 14. ●Curcuma longa (Turmeric)बेसार ●Using turmeric for yeast infections seems to be an excellent natural remedy. ●Many studies have demonstrated the antifungal activity of curcumin on Candida strains and various other types of fungi. Candida albican infection
- 15. ● Pongamia glabra(Karanj) करंज ●The root, bark, leaves, flower and seeds of Pongamia pinnata (L.) Pierre possesses medicinal properties and used as medicine. ●In Ayurveda and Unani, the plant is used for anti-inflammatory, antiplasmodial, anti-nonciceptive, antihyperglycamic, anti- lipidperoxidative, antidiarrhoeal, anti-ulcer, anti-hyperammonic and antioxidant activity (Chopade et al., 2008). ● The antifungal activity of the plant extracts was found mainly against the Candida albicans, Epidermophyton floccosum. Candida albicans infection
- 16. •● Azadirachta indica-Neem(नीम) ●Neem has demonstrated antifungal activity and is very successful against fungi. ●The genus Trichophyton, Microsporum and Epidermophyton are an important source of dermatophytic infections in several parts of the body. ●Both the neem leaves and seed oil extracts were capable of inhibit the growth of T. mentagrophytes, T. rubrum, E. floccosum and M. canis. Microsporum canis is typically transmitted from dogs or cats ...
- 17. ● Cassia alata(दादमुददन) ● Leaves are used in skin diseases particularly in ring worm. Root is dried and powdered with Terminalia chebula in equal ratio and this mixture is also used to cure ring worm. ●It is also used to cure venereal diseases such as syphilis and gonorrhea
- 18. INDIGENOUS ANTHELMINTIC ●Areca catechu(Nut)सुपारी ●Azardirachta indica (Neem) नीम ●Carica papaya (Papita) पपीता ●Punica grantum (अनार)
- 19. ●Azardirachta indica (Neem)नीम ●In sheep, neem water extracts was 53.72% effective against Haemonchus contortus [Rob et al.,2004]. Haemonchu worm Haemonchu egg Anaemia due to Haemonchu
- 20. ●Carica papaya (Papita)पपीता ●Okeniyi et al., (2007) who reported 71 - 100% worm clearance in asymptomatic children administered with C. papaya seeds and honey. ●Carica papaya seeds contain many biologically active compounds mainly parpain and benzylisothiocyanate (Nwofia et al., 2012). ●The Infusa of papaya (Carica papaya L.) Seed has anthelmintic effect against Ascaris suum in vitro (Maulidila Briliana Agarti et al.,2017).
- 21. ●Punica grantum (अनार) ●Punicagranatum (anar) is another herbal anthelmintic drug widely used in ayurveda. The most famous usage worldwide has been a vermifugal or taenicidal agent i.e. a killer and expeller of intestinal worms (Subhedar et al. 2011). The anthelmintic activity may be chiefly due to alkaloids. ● It is likely that at higher concentration all binding receptors on the worms were occupied thus leading to hyperpolarization of membranes, limiting excitation and impulse transmission causing flaccid paralysis of worm muscle, a similar observation made by Wasswa and Olila (2006). ●P. granatum exhibited significant in vitro anthelmintic activity against G. indicus of sheep and have potential for use as an alternative anthelmintic agent for the control of gastrointestinal helminths of sheep and other ruminants.
- 22. ●Areca catechu (Betel nut) सुपारी ●Betel nut has showed better results and an in vivo anthelmintic effect at 30 gm/20 kg body weight against roundworms and tapeworms of small ruminants and native chickens (Peng et al. 2015). ● Arecholine, active ingredient found in betel nut, inhibits the gamma amino benzoic acid that causes paralysis of the helminths [Orazaga et al., 2017].
- 23. References Chopade VV, TankarAN, Pande VV, Tekade AR, Gowekar NM, Bhandari SR, Khandake SN. [2008] Pongamia pinnata: Phytochemical constituents, traditional uses and pharmacological properties: A review. Int J Green Pharm; 2: 72- 75. Peng W, Liu YJ, Wu N, Sun T, He XY, Gao YX, et al. Areca catechu L. (Arecaceae): a review of its traditional uses, botany, phytochemisty, pharmacology and toxicology. J Ethno Pharmacol 2015; 164:340–56; h Orazaga MSI, Orazaga BP. Efficay of Ipil-ipil (Leucaena leucocephala), Betel Nut (Arecha catechu) and Papaya (Carica papaya) seeds against roundworms of Darag Native Chicken. Philippine J Vet Anim Sci 2017. 43(1):33–7 Rob S, Mostofa M, Awal MA, Shahiduzzaman M, Sardar SA. Comparative efficacy of albendazole (Endokil) and neem (Azadirachta indica) leaves extract against hemonchosis in sheep. Progress Agr 2004; 15(2):33–9. Subhedar S, Goswami P, Rana N, Gupta A, Shukla P. Herbal alternatives: anthelmintic activity of Punica granatum (Pomegranate) Int J Drug Discov Herb Res. 2011;1(3):150–152. Okeniyi, J.A., Ogunlesi, T.A., Oyelami, O.A. and Adeyemi, L.A. (2007). Effectiveness of dried Carica papaya seeds against human intestinal parasitosis: A pilot study. Journal of Medicine and Food. 10, 194-196 Maulidila Briliana Agarti, Muhammad Ibrahim, Salma Alfiana, Sekentya Mauridha Sasturi, EM Sutrisna,2017. THE ACTIVITIES OF ANTHELMINTIC INFUSA OF PAPAYA SEEDS (CARICA PAPAYA L.) AGAINST WORMS ASCARIS SUUM (STUDY IN VITRO) J.Bio.Innov 6 (5), pp: 659-663,)