CLINICAL TRIALS

India develops first indigenously discovered antibiotic "Nafithromycin" effective against resistant respiratory infections
India has proudly introduced Nafithromycin, its first homegrown antibiotic, tackling stubborn respiratory infections with groundbreaking efficacy. Coupled with a significant leap in gene therapy for Haemophilia, these innovations underscore India's commitment to self-sufficiency in the pharmaceutical arena. The country is now embracing a model that fosters collaboration with the private sector, setting the stage for international acclaim in biomedical research.

Tiny fruit, healthier bread, and a daily drink: Study reveals 3 surprising natural remedies to beat constipation
A new guideline from the British Dietetic Association identifies three simple remedies for constipation: kiwi, rye bread, and mineral-rich water. Published in the Journal of Human Nutrition and Dietetics, the findings challenge the long-held “more fiber” advice by showing these specific foods work better than generic diets. With evidence from 75 trials, the recommendations offer an easy, natural way to support digestion, providing practical relief for millions worldwide.

Prerna launches CANTEL™: A MicroRNA-based blood test for breast cancer screening
PrecisionRNA Biotech from Hyderabad has launched Cantel, a new microRNA blood test for breast cancer screening. This test offers a simple and accurate alternative to traditional methods. It aims to improve early detection rates in India. Cantel is designed for women aged 30 and above. The company is seeking investors for nationwide expansion.

Praxis Precision Medicines stock jumps over 235% today- Here’s why investors are paying attention
PRAX stock: Praxis Precision Medicines stock saw a massive surge of over 235 percent. This happened after positive results from a Phase 3 clinical trial for ulixacaltamide, a drug for essential tremor. The company plans to submit a New Drug Application to the FDA by early 2026. Analysts have given the stock a strong buy rating.

CDSCO seeks views on level playing field for new drugs
In a significant shift for the pharmaceutical market, India's drug regulator is crafting new legislation regarding drug approvals. Under this proposal, the first entity to introduce a novel drug will be mandated to perform clinical trials, while subsequent entrants will be allowed to forego these tests.

AI lab Lila Sciences tops $1.3 billion valuation with new Nvidia backing
The latest funding brings Lila's total Series A to $350 million and overall capital raised to $550 million, reflecting strong investor appetite for AI-driven scientific discovery.
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Deadly fatty liver could be reversed with this surprising two-drug heart combo, as per doctors
Doctors have found hope for fatty liver disease using two common heart drugs. The new study from the University of Barcelona shows this combo might help reduce liver fat and improve liver health. More tests on humans are needed, but experts say it could be a big step in treating fatty liver safely.
Nagaland University-led study finds tea blossoms rich in health-boosting compounds
A new study reveals tea blossoms hold significant health potential. These flowers, usually discarded, are packed with beneficial compounds. Researchers believe they can be used for natural health supplements and drinks. This discovery could reduce agricultural waste and boost rural economies. India is poised to become a leader in these new plant-based products.
Novo Nordisk to acquire Akero Therapeutics for $4.7 billion — Akero stock jumps 20%, Novo Nordisk stock falls, here’s all about the deal
Akero Therapeutics stock surged nearly 20% today. Novo Nordisk announced it will acquire Akero for $4.7 billion in cash. The deal values Akero shares at $54 each, plus up to $6 more if FDA approves Akero’s lead drug, Efruxifermin, for metabolic disease treatment. This acquisition strengthens Novo Nordisk’s position in metabolic and liver diseases. The buyout is expected to close by early 2026, pending approvals. Novo Nordisk anticipates higher R&D costs in 2026 but no impact on 2025 profits.
China surgeons perform first Pig-to-Human Liver Transplant. Ray of hope for cancer patients?
American surgeons have in recent years transplanted hearts and kidneys from genetically modified pigs into a small number of living patients, they have shied away from liver xenotransplantation, which poses particularly complex challenges.
Ahmedabad civic body receives complaints about 'lapses' by labs in clinical trials on humans
Ahmedabad Municipal Corporation has alerted the Gujarat FDCA regarding complaints of clinical trial lapses. Allegations include inadequate care for participants during and after trials, and unauthorized videography of subjects. The corporation has forwarded these details for further investigation and action.
Forget long workouts: Study says 5-minute ‘exercise snacks’ can boost heart and muscle health more effectively
A new study published in BMJ Sports Medicine suggests that short, deliberate bursts of activity — dubbed “exercise snacks” — can significantly enhance fitness, especially for inactive adults. These quick routines, lasting under five minutes, such as stair climbing or brisk walking, were shown to boost heart and muscle health, improve endurance, and encourage consistency, offering an easier, time-efficient alternative to traditional long workouts.
Scientists reverse Alzheimer’s in mice — breakthrough sparks hope for humans
A new treatment shows promise in reversing Alzheimer's disease. Scientists used nanoparticles to help the brain clear toxic buildup. This therapy restored the blood-brain barrier's function in mice. Researchers observed significant improvements in brain function and behavior. Human trials could begin in a few years, offering hope for a cure.
Is Malaika Arora’s morning jeera-ajwain drink good for you? Gastro doctor Dr Pal says it can help you lose weight
Actress Malaika Arora's viral video sparked renewed interest in a traditional jeera and ajwain drink. Gastroenterologist Dr. Pal Manickam and Ayurveda practitioner Dr. Ayush Varma discuss its digestive, metabolic, and potential weight management benefits, highlighting the combined power of cumin, carom, and fennel seeds.
Nobel winner Fred Ramsdell unreachable, hiking 'off the grid'
Fred Ramsdell, a Nobel laureate for immune system research, is currently unreachable. He is on an off-the-grid hiking trip and unaware of his 2025 Nobel Prize win. The Nobel committee and his colleagues are trying to contact him. Ramsdell shared the prize with Mary Brunkow and Shimon Sakaguchi for their work on regulatory T-cells.
Huntington's disease cure is possible through new treatment, reveals study. Check symptoms, what causes illness
Huntington's disease findings were announced last month in a news release from uniQure, the company that sponsored the research.
Meet Brunkow, Ramsdell & Sakaguchi — Nobel Prize-winning trio who taught the world how the immune system knows when to stop
Shimon Sakaguchi, Mary E. Brunkow, and Fred Ramsdell received the 2025 Nobel Prize in Medicine for decoding peripheral immune tolerance. Sakaguchi discovered regulatory T cells, while Brunkow and Ramsdell identified the Foxp3 gene controlling them. Their groundbreaking work transformed immunology, offering new avenues for treating autoimmune disorders, cancer, and transplant rejection.
Nobel Prize 2025 in Medicine awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi for discoveries in immune tolerance
The 2025 Nobel Prize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance,” a breakthrough that has transformed understanding of how the body prevents the immune system from attacking its own tissues.
Harvard-trained doctor suggest 10 foods to reduce bloating, improve digestion
Harvard-trained gastroenterologist Dr. Saurabh Sethi recommends 10 foods to help reduce common post-meal bloating and improve digestion. These include enzyme-rich fruits like kiwi and papaya, hydrating cucumber, fiber-packed chia seeds and oats, and soothing ginger and peppermint. These natural remedies support gut health, though persistent severe symptoms require medical attention.
3 drinks to reverse fatty liver: Harvard doctor recommends science-backed healthy beverages
Fatty liver disease is increasingly common due to obesity, poor diet, and sedentary lifestyles, often progressing silently and potentially leading to serious liver complications. Dr Saurabh Sethi, a gastroenterologist trained at AIIMS, Harvard, and Stanford, recommends three science-backed drinks—green tea, coffee, and beet juice—that can support liver health. Green tea provides antioxidants that reduce fat buildup, coffee may lower the risk of fibrosis and inflammation, and beet juice contains betalains that protect liver cells.
Exploring the benefits of this ancient Chinese therapy still thriving today
Gua sha, a 2,000-year-old Chinese therapeutic scraping technique, is gaining recognition for its potential health benefits. It involves scraping skin to stimulate circulation and healing, reportedly easing pain, inflammation, and perimenopausal symptoms. While generally safe, it causes temporary bruising and is unsuitable for individuals with certain medical conditions, serving best as a complementary therapy.
Is the government still shut down today? Details you must know
The U.S. government remains shut down as of October 3, 2025. Congress has not reached a deal to fund federal agencies. Millions of Americans are already feeling the effects. From federal workers to families relying on assistance programs, the shutdown is leaving a wide impact across the country.
'It may sound crazy, but...': Cardiologist reveals 5 futuristic heart treatments set to become the new normal in heart care
Cardiologist Dr. Dmitry Yaranov, widely known as @heart_transplant_doc, has outlined what he calls the “crazy future of heart care” in a viral Instagram post. The Memphis-based transplant expert highlighted five groundbreaking treatments: lab-grown hearts from patients’ own cells, gene editing to prevent disease, pig heart transplants, mRNA-based repair therapies, and nervous system rewiring devices. He stressed that these futuristic treatments are already moving from labs to clinical trials, redefining cardiology’s future.
Novo, Lilly weight-loss drugs should be first option obesity treatments, European doctors say
Semaglutide, the active ingredient in Novo's Wegovy and Ozempic, and tirzepatide, sold as Zepbound and Mounjaro by Lilly, are so effective that they should be the first choice in almost all cases when substantial weight loss is necessary, according to a new guideline from the European Association for the Study of Obesity published in Nature Medicine.
Elon Musk becomes first person to hit $500 billion in net worth: All you need to know
Elon Musk became the first person with a net worth of $500 billion, driven by Tesla’s stock rebound and the rising value of his ventures, including SpaceX and xAI. Tesla aims for AI, robotaxis, and humanoid robots, while xAI and SpaceX pursue ambitious growth and funding plans.
Pricing depends on the country, Bayer looks at affordability: Executive
India has evolved significantly in the clinical trial setting...we have a significant number of patients and trials running in IndiaAshraf Al-Ouf Head, Pharmaceutical Commercial Ops, APAC, Bayer
Indian pharma Wockhardt seeks US approval for new drug to treat UTIs
Wockhardt has submitted a New Drug Application to the USFDA for its novel antibacterial agent, Zidebactam-Cefepime injection. This drug targets complicated urinary tract infections, including those caused by multidrug-resistant Gram-negative bacteria. This marks a significant milestone as the first USFDA NDA for a drug fully discovered and developed by an Indian pharmaceutical company, following successful global Phase III trials.
Highs & Lows: Could the microdosing of psychedelics be a key missing piece in the mental health jigsaw?
A Netflix documentary highlights the re-evaluation of mind-expanding substances like LSD, once banned but now experiencing a scientific renaissance. New research, including a study on pharmaceutical LSD for anxiety, suggests these psychedelics could redefine mental health treatment. However, overcoming public demonisation and ensuring rigorous scientific trials are crucial for their widespread acceptance.
Study reveals how an accessible medicine could help prevent colorectal cancer relapse
Low-dose aspirin may help prevent colorectal cancer relapse in patients with certain genetic mutations. A new study found daily aspirin can reduce cancer coming back by up to 55%. Researchers say it works by reducing inflammation, stopping tumor growth, and targeting cancer cells. This cheap and widely available drug could save many lives if used carefully.
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