Open Source Python Sound/Audio Software

Airtime lets you take total control of your radio station via the web with intelligent archive management, powerful search, an easy playlist builder, a simple scheduling calendar and rock-solid automated playout. Features include Smart Blocks, live assist modes, WAV, FLAC, AAC, MP3 and OGG support, fades, cues, playlists, programme calendar, Icecast, Shoutcast and Soundcloud integration, DJ and station manager roles, JQuery widgets, Liquidsoap playout, and a record and rebroadcast functionality. Powerful media archive features 'watch' folders to allow stations to magically synchronise files, auto-import files and has multiple directory support. Airtime is free to download, runs on Ubuntu and Debian, and users can interact with it through any web browser. Airtime now comes with an 'easy install' package.

Acará is an easy-to-use DVD creator for Unix* build with PyQt4

Bunghole Jukebox is a web interface to your MP3 collection. Use it to access your music collection wherever you are, publish in your website/blog and share with friends.

This is a simple assistant written in Python language for video capture in HD definition, using HDPVR of Hauppage!.

XBMC Media Center is a free cross-platform media player software and entertainment system application framework for Linux, Mac, and Windows. XBMC is capable of playing back and streaming all popular video, audio, and picture formats out-of-the-box.

figusdevpack (fdp), is designed for reducing application development time and acquainting new users with existing resources for multimedia development. It is structured around a wrapper library, example applications, tutorials and documentation.

Simple music organizer.

A simple software that speaks a text. You can type the text or appoint a file. Fala is just a frontend to festival. It's designed for GNOME, but if you have gtk, pyhton and festival you are able to run it.