Compare the Top Disease Management Software in the USA as of January 2026

What is Disease Management Software in the USA?

Disease management software is designed to help healthcare providers monitor and manage chronic conditions and diseases more effectively. It integrates patient data, tracking symptoms, medications, and treatment plans, allowing for more personalized care. The software often includes tools for patient education, reminders, and communication, helping patients stay on track with their health goals. Additionally, it provides healthcare professionals with real-time analytics and reports to make informed decisions. By streamlining care coordination, disease management software aims to improve patient outcomes and reduce healthcare costs. Compare and read user reviews of the best Disease Management software in the USA currently available using the table below. This list is updated regularly.

  • 1
    Perfect E-Prescription System
    The Perfect E-Prescription System is a sophisticated software solution designed to enhance the efficiency and safety of the prescription process in healthcare settings. By enabling healthcare providers to electronically send prescriptions directly to pharmacies, it reduces the risk of errors and ensures that patients receive their medications promptly. The system includes features for managing medication histories, checking drug interactions, and accurately dosing, which altogether streamline the prescription lifecycle. Additional functionalities include the ability to manage and authorize prescription refills, which aids in chronic disease management, and real-time tracking of prescription status, which keeps both providers and patients informed. Integration with Perfect Pharmacy Manager ensures seamless workflow between prescribing and dispensing medications, thereby optimizing operational efficiency and improving patient outcomes.
    Starting Price: $5/month
  • 2
    aTouchAway

    aTouchAway

    Aetonix Systems

    Through virtual communication, remote patient monitoring, care plan management, and clinical workflows, the aTouchAway platform dramatically improves patient outcomes. Communicate with patients, caregivers, care team members, and anyone else in the circle of care through a secure private health information platform supporting video conferencing, messages, and group chat. Engage in two-way video calls between you and the patient, with the ability to add a third person. Technology-challenged patients can initiate a video call with one simple touch. Send secure text messages between circle of care members or group chats. Conversations are encrypted to safeguard patients’ health information. Send and receive images, videos, and documents as attachments in text messages or group chats. Files are stored temporarily and expire after 72 hours to protect confidentiality.
    Starting Price: $15 per month
  • 3
    ChronicCareIQ

    ChronicCareIQ

    ChronicCareIQ

    ChronicCareIQ’s award-winning technology integrates remote patient monitoring, chronic care management, and telemedicine to connect you to your patients, optimize reimbursement and minimize documentation, all for one low monthly fee. ChronicCareIQ is a remote care management solution that helps doctors and hospitals generate and sustain net new recurring revenue through monitoring and e-visits for chronic care management, remote patient monitoring, and transitional care management programs. Our simple-to-use, turnkey solution empowers physicians to connect with their patients by utilizing technology patients already have, including smartphones, tablets, computers, and even landlines. Mitigate disease progression by extending care oversight outside your practice and into the patient’s home. Get paid for the work your staff is already performing while boosting care quality and patient satisfaction.
    Starting Price: Free
  • 4
    GoMo Health

    GoMo Health

    GoMo Health

    GoMo Health offers behavioral and cognitive-based patient engagement solutions that help reduce costs for organizations. We achieve desired outcomes by designing personalized, scalable, simple, and cost-effective programs, which are also easy to implement and market. Our evidence-based BehavioralRx® lifestyle modification science addresses the whole person – psychosocial, emotional, and physical – to promote better self-management and healthy decision-making. Trusted and embraced by leading providers, plans, employers, pharma, medical device, and consumer health and wellness organizations for audiences across the healthcare and life science continuum.
    Starting Price: $25/month
  • 5
    ChronicWatch

    ChronicWatch

    ChronicWatch

    With a completely automated end-to-end, exception-based patient care management system, better outcomes are just a phone call away. Care Assister is a digital health assistant that uses machine learning to enhance your CCM offering, foster patient relationships, and deliver value for you and your patients every single day. Plus its supported by our experienced staff of medical assistants available 24/7 to drive Medicare and help you provide the best quality of care. We take good care of your patients by providing 24/7 access to care, keep them motivated by providing them with personalized care plans and help them achieve their goals through our targeted rewards program. Our dashboards and alerts ensure 100% coverage across enrolled patients to maximize your billing and our patient engagement increases your revenue by maximizing patient retention month after month.
  • 6
    Datos Health

    Datos Health

    Datos Health

    Design a hybrid care delivery model that goes beyond remote patient monitoring and alerting with automated remote care. Customize care plans to your needs and empower patients to manage parts of their care journey themselves. One app that supports all use cases, increasing adoption and patient engagement. Your protocols and your logic become automated care workflows, immediately updated with every tweak and change. Scale your remote care program with a platform centered around clinicians and patients. We’re stuck with a mess of narrowly focused, rigid solutions we can’t do anything about. Solutions that dictate to us how to do care. Do it yourself or leverage protocols from leading healthcare organizations and make them your own, only better.
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