1.
Which of the following is wrong concerning the Philadelphia chromosome:
A shortening of long arm of chromosome 22
B Philadelphia –ve cases have bad prognosis
C diagnostic of CML
D found in lymphocytes
2. the commonest cause of jaundice in thalassemia is:
A viral hepatitis c
B iron deposition in liver
C viral hepatitis B
D haemolysis
3. Waldeyer's ring does not include:
A faucal tonsils
B submandibular glands
C denoids
D lingual tonsils
4. whitch of the following anemias is associated with splenomegaly:
A. chronic renal failure
B. aplastic anemia
C. hereditary spherocytosis
D. sickle cell anaemia
5. all may cause abdominal pain in thalassemia major except:
A. vasculitis
B. splenic infarction
C. dragging pain dt huge splenomegaly
D. pigment stones in gall bladder
6. Virchow's node receives lymphatics from all except:
A. testes
B. stomach
C. prostate
D. breast
7. all produce microcytic anemia except:
A. sideroblastic an.
B. thalassemia
C. pernicious anemia
D. lead poisoning
1
8. Basophilic stippling is classically seen in:
A. CML
B. myelosclerosis
C. chronic lead poisoning
D. iron def anemia
9. Increase Fe & normal TIBC are found in:
A. thalassemia major
B. haemosidrosis
C. rheumatoid arthritis
D. dissiminated malignancy
10. Non-thrombocytopenic purpurais seen in all except:
A. a-vasculitis
B. b-uraemia
C. c-hereditary haemorrhagic telangectasia
D. d-SLE
11. Gum bleeding is characteristic of all except:
A. chronic phenytoin therapy
B. aplastic an.
C. scurvy
D. haemophilia
12. Which of the following is not true in thrombasthenia:
A. prolonged bleeding time
B. normal platlet Count
C. platelet Aggregation defect
D. prolonged clotting time
13. Which is not associated with hypersplenism:
A. splenomegaly
B. pancytopenia
C. hypercellular bone marrow
D. reversibility by splenectomy
14. splenectomy is curative in:
A. G6PD def.
B. ITP
C. thalassemia
D. hereditary sphrocytosis
2
15. Plummer Vinson syndrome is not associated with:
A. angular stomatitis
B. splenomegaly
C. clubbingd
D. post cricoid web
16. haemolytic anemia is not produced by:
A. penicillin
B. lithium
C. Quinidine
D. methyldopa
17. sideroblastic anemia may be treated by all except:
A. pyridoxine
B. hydroxy urea
C. desferroxamine
D. androgens
18. Henoch schonlien purpura is not associated with:
A. thrombocytopenia
B. palpable purpura
C. intussusception
D. acute diffuse glomerulonephritis
19. Outstanding feature of ITP:
A. fever
B. gum bleeding
C. moderate splenomegaly
D. sterna tenderness
20. Thrombocytopenia is absent in:
A. DIC
B. Wiskottt Aldrich syndrome
C. Henoch schonlien purpura
D. myelosclerosis
21. Cooley's anemia is:
A. Sickle cell an.
B. thalassemia major
C. high ESR
D. aplastic an.
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22. presence of an .–jaundice –splenomegaly with increase MCH is seen in:
A. liver cirrhosis
B. [Link]
C. PNH
D. herditary spherocytosis
23. all may complicate BM transplantation except:
A. cataract formation
B. leucoencephalopathy
C. cardiomyopathy
D. emphysema
24. incorrect about pernicious an:.
A. hyperchlorhydria
B. premature graying of hair
C. anti intrinsic factor antibody in 60℅ of pts.
D. gastric polyp may occur
25. Busulfan therapy lead to all except:
A. hyperpigmentation
B. pulm .Fibrosis
C. optic neuritis
D. BM suppression
26. increase serum iron –decrease IBC a feature of:
A. Hookworm infestation
B. sideroblastic an
C. alcoholic liver dis.
D. th. major
27. hepato-splenomegaly with lymphadenopathy occur in all except:
A. ALL
B. lymphoma
C. CML
D. dissiminated TB
28. sickle cell an .Is not complicated by:
A. papillary necrosis
B. pancreatitis
C. osteomyelitis
D. CHF
4
29. decrease iron &decrease iron binding capacity are seen in:
A. recurrent GIT bleeding
B. intestinal resection
C. chronic infection
D. menorrhagia
30. Platlet transfusion is not indicated in:
A. aplastic an.
B. uraemia with bleeding